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Winslow RL, Cortassa S, Greenstein JL (2005) Using models of the myocyte for functional interpretation of cardiac proteomic data. J Physiol 563:73-81 [PubMed]

References and models cited by this paper

References and models that cite this paper

Alseikhan BA, DeMaria CD, Colecraft HM, Yue DT (2002) Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation. Proc Natl Acad Sci U S A 99:17185-90 [Journal] [PubMed]

Beuckelmann DJ, Erdmann E (1992) Ca(2+)-currents and intracellular [Ca2+]i-transients in single ventricular myocytes isolated from terminally failing human myocardium. Basic Res Cardiol 87 Suppl 1:235-43 [PubMed]

Beuckelmann DJ, Näbauer M, Erdmann E (1993) Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ Res 73:379-85 [PubMed]

Chen-Izu Y, Xiao RP, Izu LT, Cheng H, Kuschel M, Spurgeon H, Lakatta EG (2000) G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels. Biophys J 79:2547-56 [Journal] [PubMed]

Cheng H, Lederer WJ, Cannell MB (1993) Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262:740-4 [PubMed]

Cortassa S, Aon MA, Marbán E, Winslow RL, O'Rourke B (2003) An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophys J 84:2734-55 [Journal] [PubMed]

   Excitation-contraction coupling/mitochondrial energetics (ECME) model (Cortassa et al. 2006) [Model]

Davare MA, Avdonin V, Hall DD, Peden EM, Burette A, Weinberg RJ, Horne MC, Hoshi T, Hell JW (2001) A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2. Science 293:98-101 [Journal] [PubMed]

DiFrancesco D, Noble D (1985) A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philos Trans R Soc Lond B Biol Sci 307:353-98 [Journal] [PubMed]

   Cardiac action potentials and pacemaker activity of sinoatrial node (DiFrancesco & Noble 1985) [Model]

Franzini-Armstrong C, Protasi F, Ramesh V (1999) Shape, size, and distribution of Ca(2+) release units and couplons in skeletal and cardiac muscles. Biophys J 77:1528-39 [Journal] [PubMed]

Ginsburg KS, Bers DM (2004) Modulation of excitation-contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger. J Physiol 556:463-80 [Journal] [PubMed]

Greenstein JL, Tanskanen AJ, Winslow RL (2004) Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processes. Ann N Y Acad Sci 1015:16-27 [Journal] [PubMed]

Greenstein JL, Winslow RL (2002) An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophys J 83:2918-45 [Journal] [PubMed]

Greenstein JL, Wu R, Po S, Tomaselli GF, Winslow RL (2000) Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration. Circ Res 87:1026-33 [PubMed]

   Kv4.3, Kv1.4 encoded K(+) channel in heart cells (Greenstein et al 2000) (XPP) [Model]
   Kv4.3, Kv1.4 encoded K channel in heart cells & tachy. (Winslow et al 1999, Greenstein et al 2000) [Model]

Herzig S, Patil P, Neumann J, Staschen CM, Yue DT (1993) Mechanisms of beta-adrenergic stimulation of cardiac Ca2+ channels revealed by discrete-time Markov analysis of slow gating. Biophys J 65:1599-612 [Journal] [PubMed]

Irvine LA, Jafri MS, Winslow RL (1999) Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation. Biophys J 76:1868-85 [PubMed]

Iyer V, Mazhari R, Winslow RL (2004) A computational model of the human left-ventricular epicardial myocyte. Biophys J 87:1507-25 [Journal] [PubMed]

Jafri MS, Rice JJ, Winslow RL (1998) Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophys J 74:1149-68 [Journal] [PubMed]

Kääb S, Nuss HB, Chiamvimonvat N, O'Rourke B, Pak PH, Kass DA, Marban E, Tomaselli GF (1996) Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circ Res 78:262-73 [PubMed]

Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circ Res 74:1071-96 [PubMed]

   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]

Mazhari R, Greenstein JL, Winslow RL, Marbán E, Nuss HB (2001) Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis. Circ Res 89:33-8 [PubMed]

Näbauer M, Beuckelmann DJ, Uberfuhr P, Steinbeck G (1996) Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle. Circulation 93:168-77 [PubMed]

NOBLE D (1960) Cardiac action and pacemaker potentials based on the Hodgkin-Huxley equations. Nature 188:495-7 [PubMed]

O'Rourke B, Kass DA, Tomaselli GF, Kääb S, Tunin R, Marbán E (1999) Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies. Circ Res 84:562-70 [PubMed]

Peterson BZ, DeMaria CD, Adelman JP, Yue DT (1999) Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channels. Neuron 22:549-58 [PubMed]

Peterson BZ, Lee JS, Mulle JG, Wang Y, de Leon M, Yue DT (2000) Critical determinants of Ca(2+)-dependent inactivation within an EF-hand motif of L-type Ca(2+) channels. Biophys J 78:1906-20 [Journal] [PubMed]

Puglisi JL, Bers DM (2001) LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport. Am J Physiol Cell Physiol 281:C2049-60 [Journal] [PubMed]

   A cardiac cell simulator (Puglisi and Bers 2001), applied to the QT interval (Busjahn et al 2004) [Model]

Rice JJ, Jafri MS, Winslow RL (2000) Modeling short-term interval-force relations in cardiac muscle. Am J Physiol Heart Circ Physiol 278:H913-31 [Journal] [PubMed]

Saucerman JJ, Brunton LL, Michailova AP, McCulloch AD (2003) Modeling beta-adrenergic control of cardiac myocyte contractility in silico. J Biol Chem 278:47997-8003 [Journal] [PubMed]

Shacklock PS, Wier WG, Balke CW (1995) Local Ca2+ transients (Ca2+ sparks) originate at transverse tubules in rat heart cells. J Physiol 487 ( Pt 3):601-8 [PubMed]

Sham JS, Cleemann L, Morad M (1995) Functional coupling of Ca2+ channels and ryanodine receptors in cardiac myocytes. Proc Natl Acad Sci U S A 92:121-5 [PubMed]

Song L-S, Wang S-Q, Xiao R-P, Spurgeon H, Lakatta_eg CHENG_H (2001) Beta-Adrenergic stimulation synchronizes intracellular Ca2+ release during excitation-contraction coupling in cardiac myocytes Circ Res 88:794-801

Stern MD (1992) Theory of excitation-contraction coupling in cardiac muscle. Biophys J 63:497-517 [Journal] [PubMed]

Tanskanen AJ, Greenstein JL, O'Rourke B, Winslow RL (2005) The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations. Biophys J 88:85-95 [Journal] [PubMed]

Wang SQ, Song LS, Lakatta EG, Cheng H (2001) Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells. Nature 410:592-6 [Journal] [PubMed]

Wier WG, Egan TM, López-López JR, Balke CW (1994) Local control of excitation-contraction coupling in rat heart cells. J Physiol 474:463-71 [PubMed]

Winslow RL, Greenstein JL, Tomaselli GF, ORourke B (2001) Computational models of the failing myocyte: relating altered gene expression to cellular function Phil Trans R Soc Lond A 359:1187-1200

Winslow RL, Rice J, Jafri S, Marbán E, O'Rourke B (1999) Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies. Circ Res 84:571-86 [PubMed]

   Kv4.3, Kv1.4 encoded K channel in heart cells & tachy. (Winslow et al 1999, Greenstein et al 2000) [Model]

Xiao R-P, Cheng H, Zhou YY, Kuschel M, Lakatta EG (1999) Recent advances in cardiac 2-adrenergic signal transduction Circ Res 85:1092-1100

Yue DT, Herzig S, Marban E (1990) Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes. Proc Natl Acad Sci U S A 87:753-7 [PubMed]

Patel SP, Campbell DL (2005) Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms. J Physiol 569:7-39 [Journal] [PubMed]

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