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Greenstein JL, Tanskanen AJ, Winslow RL (2004) Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processes. Ann N Y Acad Sci 1015:16-27 [PubMed]

References and models cited by this paper

References and models that cite this paper

Bers DM (2002) Cardiac excitation-contraction coupling. Nature 415:198-205 [Journal] [PubMed]

Chen-Izu Y, Xiao RP, Izu LT, Cheng H, Kuschel M, Spurgeon H, Lakatta EG (2000) G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channels. Biophys J 79:2547-56 [Journal] [PubMed]

Cheng H, Lederer WJ, Cannell MB (1993) Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262:740-4 [PubMed]

Dzhura I, Wu Y, Colbran RJ, Balser JR, Anderson ME (2000) Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol 2:173-7 [Journal] [PubMed]

Dzhura I, Wu Y, Colbran RJ, Corbin JD, Balser JR, Anderson ME (2002) Cytoskeletal disrupting agents prevent calmodulin kinase, IQ domain and voltage-dependent facilitation of L-type Ca2+ channels. J Physiol 545:399-406 [PubMed]

Franzini-Armstrong C, Protasi F, Ramesh V (1999) Shape, size, and distribution of Ca(2+) release units and couplons in skeletal and cardiac muscles. Biophys J 77:1528-39 [Journal] [PubMed]

Ginsburg KS, Bers DM (2001) Isoproterenol does not increase the intrinsic gain of cardiac excitation-contraction coupling (ECC) Biophys J 80:590

Greenstein JL, Winslow RL (2002) An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophys J 83:2918-45 [Journal] [PubMed]

Greenstein JL, Wu R, Po S, Tomaselli GF, Winslow RL (2000) Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration. Circ Res 87:1026-33 [PubMed]

   Kv4.3, Kv1.4 encoded K(+) channel in heart cells (Greenstein et al 2000) (XPP) [Model]
   Kv4.3, Kv1.4 encoded K channel in heart cells & tachy. (Winslow et al 1999, Greenstein et al 2000) [Model]

Handrock R, Schröder F, Hirt S, Haverich A, Mittmann C, Herzig S (1998) Single-channel properties of L-type calcium channels from failing human ventricle. Cardiovasc Res 37:445-55 [PubMed]

Heath BM, Terrar DA (2000) Protein kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes. J Physiol 522 Pt 3:391-402 [PubMed]

Herzig S, Patil P, Neumann J, Staschen CM, Yue DT (1993) Mechanisms of beta-adrenergic stimulation of cardiac Ca2+ channels revealed by discrete-time Markov analysis of slow gating. Biophys J 65:1599-612 [Journal] [PubMed]

Hobai IA, O'Rourke B (2001) Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation 103:1577-84 [PubMed]

Imredy JP, Yue DT (1994) Mechanism of Ca(2+)-sensitive inactivation of L-type Ca2+ channels. Neuron 12:1301-18 [PubMed]

Jafri MS, Rice JJ, Winslow RL (1998) Cardiac Ca2+ dynamics: the roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophys J 74:1149-68 [Journal] [PubMed]

Kääb S, Nuss HB, Chiamvimonvat N, O'Rourke B, Pak PH, Kass DA, Marban E, Tomaselli GF (1996) Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circ Res 78:262-73 [PubMed]

Kathöfer S, Zhang W, Karle C, Thomas D, Schoels W, Kiehn J (2000) Functional coupling of human beta 3-adrenoreceptors to the KvLQT1/MinK potassium channel. J Biol Chem 275:26743-7 [Journal] [PubMed]

Keizer J, Smith GD (1998) Spark-to-wave transition: saltatory transmission of calcium waves in cardiac myocytes. Biophys Chem 72:87-100 [PubMed]

Kubicek, Marek MM (1983) Computational Methods Bifurcation Theory and Dissipative Structures

Li Y, Kranias EG, Mignery GA, Bers DM (2002) Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circ Res 90:309-16 [PubMed]

Marks AR (2001) Ryanodine receptors/calcium release channels in heart failure and sudden cardiac death. J Mol Cell Cardiol 33:615-24 [Journal] [PubMed]

Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR (2000) PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101:365-76 [PubMed]

Matsumoto M (1998) Mersenne Twister: A 623-dimensionally equidistributed uniform pseudo-random number generator ACM Trans Model Comput Sim 8:3-30

Mazhari R, Greenstein JL, Winslow RL, Marbán E, Nuss HB (2001) Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis. Circ Res 89:33-8 [PubMed]

McDonald TF, Cavalié A, Trautwein W, Pelzer D (1986) Voltage-dependent properties of macroscopic and elementary calcium channel currents in guinea pig ventricular myocytes. Pflugers Arch 406:437-48 [PubMed]

Parker I, Zang WJ, Wier WG (1996) Ca2+ sparks involving multiple Ca2+ release sites along Z-lines in rat heart cells. J Physiol 497 ( Pt 1):31-8 [PubMed]

Press WH, Teukolsky SA, Vellerling WT, Flannery BP (1992) Numerical Recipes In C: The Art Of Scientific Computing

Priori SG, Corr PB (1990) Mechanisms underlying early and delayed afterdepolarizations induced by catecholamines. Am J Physiol 258:H1796-805 [Journal] [PubMed]

Quadbeck J, Reiter M (1975) Adrenoceptors in cardiac ventricular muscle and changes in duration of action potential caused by noradrenaline and isoprenaline. Naunyn Schmiedebergs Arch Pharmacol 288:403-14 [PubMed]

Rose WC, Balke CW, Wier WG, Marban E (1992) Macroscopic and unitary properties of physiological ion flux through L-type Ca2+ channels in guinea-pig heart cells. J Physiol 456:267-84 [PubMed]

Schröder F, Handrock R, Beuckelmann DJ, Hirt S, Hullin R, Priebe L, Schwinger RH, Weil J, Herzig S (1998) Increased availability and open probability of single L-type calcium channels from failing compared with nonfailing human ventricle. Circulation 98:969-76 [PubMed]

Shannon TR, Ginsburg KS, Bers DM (2000) Reverse mode of the sarcoplasmic reticulum calcium pump and load-dependent cytosolic calcium decline in voltage-clamped cardiac ventricular myocytes. Biophys J 78:322-33 [Journal] [PubMed]

Simmerman HK, Jones LR (1998) Phospholamban: protein structure, mechanism of action, and role in cardiac function. Physiol Rev 78:921-47 [Journal] [PubMed]

Song LS, Sham JS, Stern MD, Lakatta EG, Cheng H (1998) Direct measurement of SR release flux by tracking 'Ca2+ spikes' in rat cardiac myocytes. J Physiol 512 ( Pt 3):677-91 [PubMed]

Song LS, Wang SQ, Xiao RP, Spurgeon H, Lakatta EG, Cheng H (2001) beta-Adrenergic stimulation synchronizes intracellular Ca(2+) release during excitation-contraction coupling in cardiac myocytes. Circ Res 88:794-801 [PubMed]

Valdivia HH, Kaplan JH, Ellis-Davies GC, Lederer WJ (1995) Rapid adaptation of cardiac ryanodine receptors: modulation by Mg2+ and phosphorylation. Science 267:1997-2000 [PubMed]

Viatchenko-Karpinski S, Györke S (2001) Modulation of the Ca(2+)-induced Ca(2+) release cascade by beta-adrenergic stimulation in rat ventricular myocytes. J Physiol 533:837-48 [PubMed]

Wang SQ, Song LS, Lakatta EG, Cheng H (2001) Ca2+ signalling between single L-type Ca2+ channels and ryanodine receptors in heart cells. Nature 410:592-6 [Journal] [PubMed]

Wier WG, Egan TM, López-López JR, Balke CW (1994) Local control of excitation-contraction coupling in rat heart cells. J Physiol 474:463-71 [PubMed]

Winslow RL, Rice J, Jafri S, Marbán E, O'Rourke B (1999) Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies. Circ Res 84:571-86 [PubMed]

   Kv4.3, Kv1.4 encoded K channel in heart cells & tachy. (Winslow et al 1999, Greenstein et al 2000) [Model]

Wu Y, Temple J, Zhang R, Dzhura I, Zhang W, Trimble R, Roden DM, Passier R, Olson EN, Colbran RJ, Anderson ME (2002) Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation 106:1288-93 [PubMed]

Xiao RP, Cheng H, Zhou YY, Kuschel M, Lakatta EG (1999) Recent advances in cardiac beta(2)-adrenergic signal transduction. Circ Res 85:1092-100 [PubMed]

Yue DT, Herzig S, Marban E (1990) Beta-adrenergic stimulation of calcium channels occurs by potentiation of high-activity gating modes. Proc Natl Acad Sci U S A 87:753-7 [PubMed]

Kharche S, Yu J, Lei M, Zhang H (2011) A mathematical model of action potentials of mouse sinoatrial node cells with molecular bases. Am J Physiol Heart Circ Physiol 301:H945-63 [Journal] [PubMed]

   Biophysically detailed model of the mouse sino-atrial node cell (Kharche et al. 2011) [Model]

Tanskanen AJ, Greenstein JL, O'Rourke B, Winslow RL (2005) The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations. Biophys J 88:85-95 [Journal] [PubMed]

Winslow RL, Cortassa S, Greenstein JL (2005) Using models of the myocyte for functional interpretation of cardiac proteomic data. J Physiol 563:73-81 [Journal] [PubMed]

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