Citation Relationships

Rubin JE, Shevtsova NA, Ermentrout GB, Smith JC, Rybak IA (2009) Multiple rhythmic states in a model of the respiratory central pattern generator. J Neurophysiol 101:2146-65 [PubMed]

   Respiratory central pattern generator network in mammalian brainstem (Rubin et al. 2009)

References and models cited by this paper

References and models that cite this paper

Abdala AP , Koizumi H, Rybak IA, Smith JC (2007) he 3-2-1 state respiratory rhythm generator hypothesis revealed by microsectioning, reduced extracellular chloride and alterations in arterial gas tensions in the in situ rat Exp Biol Abstr 610.4

Abdala AP, Rybak IA, Smith JC, Paton JF (2007) Brainstem origins and mechanisms of abdominal expiratory activity in the rat in situ Soc Neurosci Abstr 627.1

Balis UJ, Morris KF, Koleski J, Lindsey BG (1994) Simulations of a ventrolateral medullary neural network for respiratory rhythmogenesis inferred from spike train cross-correlation. Biol Cybern 70:311-27 [PubMed]

Bianchi AL, Denavit-Saubié M, Champagnat J (1995) Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol Rev 75:1-45 [Journal] [PubMed]

Botros SM, Bruce EN (1990) Neural network implementation of a three-phase model of respiratory rhythm generation. Biol Cybern 63:143-53 [PubMed]

Butera RJ, Rinzel J, Smith JC (1999) Models of respiratory rhythm generation in the pre-Bötzinger complex. I. Bursting pacemaker neurons. J Neurophysiol 82:382-97 [Journal] [PubMed]

   Respiratory pacemaker neurons (Butera et al 1999) [Model]

Butera RJ, Rinzel J, Smith JC (1999) Models of respiratory rhythm generation in the pre-Bötzinger complex. II. Populations Of coupled pacemaker neurons. J Neurophysiol 82:398-415 [Journal] [PubMed]

Cohen MI (1979) Neurogenesis of respiratory rhythm in the mammal. Physiol Rev 59:1105-73 [Journal] [PubMed]

Curtu R, Shpiro A, Rubin N, Rinzel J (2008) Mechanisms for Frequency Control in Neuronal Competition Models. SIAM J Appl Dyn Syst 7:609-649 [Journal] [PubMed]

Daun S, Rubin JE, Rybak IA (2009) Control of oscillation periods and phase durations in half-center central pattern generators: a comparative mechanistic analysis. J Comput Neurosci 27:3-36 [Journal] [PubMed]

Del Negro CA, Morgado-Valle C, Feldman JL (2002) Respiratory rhythm: an emergent network property? Neuron 34:821-30 [PubMed]

Duffin J (1991) A model of respiratory rhythm generation. Neuroreport 2:623-6 [PubMed]

Duffin J, Ezure K, Breathing LIPSKI_J (1995) Breathing rhythm generation: focus on the rostral ventrolateral medulla News Physiol Sci 10:133-140

Duffin J, Tian GF, Peever JH (2000) Functional synaptic connections among respiratory neurons. Respir Physiol 122:237-46 [PubMed]

Dutschmann M, Herbert H (2006) The Kölliker-Fuse nucleus gates the postinspiratory phase of the respiratory cycle to control inspiratory off-switch and upper airway resistance in rat. Eur J Neurosci 24:1071-84 [Journal] [PubMed]

Ermentrout GB (1994) Reduction of conductance based models with slow synapses to neural networks. Neural Computation 6:679-695

Ermentrout GB (2002) Simulating, Analyzing, and Animating Dynamical System: A Guide to XPPAUT for Researchers and Students Society for Industrial and Applied Mathematics (SIAM)

Ezure K (1990) Synaptic connections between medullary respiratory neurons and considerations on the genesis of respiratory rhythm. Prog Neurobiol 35:429-50 [PubMed]

Ezure K, Tanaka I, Kondo M (2003) Glycine is used as a transmitter by decrementing expiratory neurons of the ventrolateral medulla in the rat. J Neurosci 23:8941-8 [PubMed]

Ezure K, Tanaka I, Saito Y (2003) Brainstem and spinal projections of augmenting expiratory neurons in the rat. Neurosci Res 45:41-51 [PubMed]

Fedorko L, Duffin J, England S (1989) Inhibition of inspiratory neurons of the nucleus retroambigualis by expiratory neurons of the Botzinger complex in the cat. Exp Neurol 106:74-7 [PubMed]

Feldman JL, Del Negro CA (2006) Looking for inspiration: new perspectives on respiratory rhythm. Nat Rev Neurosci 7:232-42 [Journal] [PubMed]

Fortuna MG, West GH, Stornetta RL, Guyenet PG (2008) Botzinger expiratory-augmenting neurons and the parafacial respiratory group. J Neurosci 28:2506-15 [Journal] [PubMed]

Gottschalk A, Ogilvie MD, Richter DW, Pack AI (1994) Computational aspects of the respiratory central pattern generator. Neural Comput 6:56-68

Grillner S (2006) Biological pattern generation: the cellular and computational logic of networks in motion. Neuron 52:751-66 [Journal] [PubMed]

Hulsmann S, Hirrlinger J, Winter SM (2007) Multiphoton imaging of rhythmic neurons of the mouse respiratory network Soc Neurosci Abstr 340.2

Janczewski WA, Feldman JL (2006) Distinct rhythm generators for inspiration and expiration in the juvenile rat. J Physiol 570:407-20 [Journal] [PubMed]

Jiang C, Lipski J (1990) Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Bötzinger complex in the cat. Exp Brain Res 81:639-48 [PubMed]

Johnson SM, Koshiya N, Smith JC (2001) Isolation of the kernel for respiratory rhythm generation in a novel preparation: the pre-Bötzinger complex "island". J Neurophysiol 85:1772-6 [Journal] [PubMed]

Kintos N, Nusbaum MP, Nadim F (2008) A modeling comparison of projection neuron- and neuromodulator-elicited oscillations in a central pattern generating network. J Comput Neurosci 24:374-97 [Journal] [PubMed]

Koizumi H, Smith JC (2008) Persistent Na+ and K+-dominated leak currents contribute to respiratory rhythm generation in the pre-Bötzinger complex in vitro. J Neurosci 28:1773-85 [Journal] [PubMed]

Koshiya N, Smith JC (1999) Neuronal pacemaker for breathing visualized in vitro. Nature 400:360-3 [Journal] [PubMed]

Kuwana S, Tsunekawa N, Yanagawa Y, Okada Y, Kuribayashi J, Obata K (2006) Electrophysiological and morphological characteristics of GABAergic respiratory neurons in the mouse pre-Bötzinger complex. Eur J Neurosci 23:667-74 [Journal] [PubMed]

Lindsey BG, Segers LS, Shannon R (1987) Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. II. Evidence for inhibitory actions of expiratory neurons. J Neurophysiol 57:1101-17 [Journal] [PubMed]

Lumsden T (1923) Observations on the respiratory centres in the cat. J Physiol 57:153-60 [PubMed]

Marder E, Bucher D (2001) Central pattern generators and the control of rhythmic movements. Curr Biol 11:R986-96 [PubMed]

Matsuoka K (1987) Mechanisms of frequency and pattern control in the neural rhythm generators. Biol Cybern 56:345-53 [PubMed]

Mironov SL (2008) Metabotropic glutamate receptors activate dendritic calcium waves and TRPM channels which drive rhythmic respiratory patterns in mice. J Physiol 586:2277-91 [Journal] [PubMed]

Morishita I, Yajima A (1972) Analysis and simulation of networks of mutually inhibiting neurons. Kybernetik 11:154-65 [PubMed]

Morrison SF, Cravo SL, Wilfehrt HM (1994) Pontine lesions produce apneusis in the rat. Brain Res 652:83-6 [PubMed]

Ogilvie MD, Gottschalk A, Anders K, Richter DW, Pack AI (1992) A network model of respiratory rhythmogenesis. Am J Physiol 263:R962-75 [Journal] [PubMed]

Pace RW, Del Negro CA (2008) AMPA and metabotropic glutamate receptors cooperatively generate inspiratory-like depolarization in mouse respiratory neurons in vitro. Eur J Neurosci 28:2434-42 [Journal] [PubMed]

Pace RW, Mackay DD, Feldman JL, Del Negro CA (2007) Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice. J Physiol 582:113-25 [Journal] [PubMed]

Pace RW, Mackay DD, Feldman JL, Del Negro CA (2007) Role of persistent sodium current in mouse preBötzinger Complex neurons and respiratory rhythm generation. J Physiol 580:485-96 [Journal] [PubMed]

Paton JF (1996) A working heart-brainstem preparation of the mouse. J Neurosci Methods 65:63-8 [PubMed]

Paton JF, Abdala AP, Koizumi H, Smith JC, St-John WM (2006) Respiratory rhythm generation during gasping depends on persistent sodium current. Nat Neurosci 9:311-3 [Journal] [PubMed]

Paton JF, Dutschmann M (2002) Central control of upper airway resistance regulating respiratory airflow in mammals. J Anat 201:319-23 [PubMed]

Rabinovich M, Volkovskii A, Lecanda P, Huerta R, Abarbanel H, Laurent G (2001) Dynamical encoding by networks of competing neuron groups: Winnerless competition Phys Rev Lett 87:68102

Rekling JC, Shao XM, Feldman JL (2000) Electrical coupling and excitatory synaptic transmission between rhythmogenic respiratory neurons in the preBötzinger complex. J Neurosci 20:RC113 [PubMed]

Richter DW (1982) Generation and maintenance of the respiratory rhythm. J Exp Biol 100:93-107 [PubMed]

Richter DW (1996) Neural regulation of respiration: Rhythmogenesis and afferent control. Comprehensive Human Physiology., Gregor R:Windhorst U, ed. pp.2079

Rubin JE, Hayes JA, Mendenhall JL, Del Negro CA (2009) Calcium-activated nonspecific cation current and synaptic depression promote network-dependent burst oscillations. Proc Natl Acad Sci U S A 106:2939-44 [Journal] [PubMed]

   Ca2+-activated I_CAN and synaptic depression promotes network-dependent oscil. (Rubin et al. 2009) [Model]

Rybak IA, Abdala AP, Markin SN, Paton JF, Smith JC (2007) Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generation. Prog Brain Res 165:201-20 [Journal] [PubMed]

Rybak IA, Paton JF, Schwaber JS (1997) Modeling neural mechanisms for genesis of respiratory rhythm and pattern. I. Models of respiratory neurons. J Neurophysiol 77:1994-2006 [Journal] [PubMed]

Rybak IA, Ptak K, Shevtsova NA, McCrimmon DR (2003) Sodium currents in neurons from the rostroventrolateral medulla of the rat. J Neurophysiol 90:1635-42 [Journal] [PubMed]

Rybak IA, Shevtsova NA, Paton JF, Dick TE, St-John WM, Mörschel M, Dutschmann M (2004) Modeling the ponto-medullary respiratory network. Respir Physiol Neurobiol 143:307-19 [Journal] [PubMed]

Rybak IA, Shevtsova NA, Ptak K, McCrimmon DR (2004) Intrinsic bursting activity in the pre-Bötzinger complex: role of persistent sodium and potassium currents. Biol Cybern 90:59-74 [Journal] [PubMed]

Rybak IA, Shevtsova NA, St-John WM, Paton JF, Pierrefiche O (2003) Endogenous rhythm generation in the pre-Bötzinger complex and ionic currents: modelling and in vitro studies. Eur J Neurosci 18:239-57 [PubMed]

Schwarzacher SW, Smith JC, Richter DW (1995) Pre-Bötzinger complex in the cat. J Neurophysiol 73:1452-61 [Journal] [PubMed]

Segers LS, Shannon R, Saporta S, Lindsey BG (1987) Functional associations among simultaneously monitored lateral medullary respiratory neurons in the cat. I. Evidence for excitatory and inhibitory actions of inspiratory neurons. J Neurophysiol 57:1078-100 [Journal] [PubMed]

Shen L, Li YM, Duffin J (2003) Inhibitory connections among rostral medullary expiratory neurones detected with cross-correlation in the decerebrate rat. Pflugers Arch 446:365-72 [Journal] [PubMed]

Shpiro A, Curtu R, Rinzel J, Rubin N (2007) Dynamical characteristics common to neuronal competition models. J Neurophysiol 97:462-73 [Journal] [PubMed]

Skinner FK, Kopell N, Marder E (1994) Mechanisms for oscillation and frequency control in reciprocally inhibitory model neural networks. J Comput Neurosci 1:69-87 [PubMed]

Skinner FK, Turrigiano GG, Marder E (1993) Frequency and burst duration in oscillating neurons and two-cell networks. Biol Cybern 69:375-83 [PubMed]

Smith JC, Abdala AP, Koizumi H, Rybak IA, Paton JF (2007) Spatial and functional architecture of the mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms. J Neurophysiol 98:3370-87 [Journal] [PubMed]

Smith JC, Butera RJ, Koshiya N, Del Negro C, Wilson CG, Johnson SM (2000) Respiratory rhythm generation in neonatal and adult mammals: the hybrid pacemaker-network model. Respir Physiol 122:131-47 [PubMed]

Smith JC, Ellenberger HH, Ballanyi K, Richter DW, Feldman JL (1991) Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254:726-9 [PubMed]

St-John WM (1998) Neurogenesis of patterns of automatic ventilatory activity. Prog Neurobiol 56:97-117 [PubMed]

Stornetta RL, Rosin DL, Wang H, Sevigny CP, Weston MC, Guyenet PG (2003) A group of glutamatergic interneurons expressing high levels of both neurokinin-1 receptors and somatostatin identifies the region of the pre-Bötzinger complex. J Comp Neurol 455:499-512 [Journal] [PubMed]

Sun Q, Goodchild AK, Pilowsky PM (2001) Firing patterns of pre-Bötzinger and Bötzinger neurons during hypocapnia in the adult rat. Brain Res 903:198-206 [PubMed]

Tian GF, Peever JH, Duffin J (1999) Bötzinger-complex, bulbospinal expiratory neurones monosynaptically inhibit ventral-group respiratory neurones in the decerebrate rat. Exp Brain Res 124:173-80 [PubMed]

Wittmeier S, Song G, Duffin J, Poon CS (2008) Pacemakers handshake synchronization mechanism of mammalian respiratory rhythmogenesis. Proc Natl Acad Sci U S A 105:18000-5 [Journal] [PubMed]

Diekman CO, Thomas PJ, Wilson CG (2017) Eupnea, tachypnea, and autoresuscitation in a closed-loop respiratory control model. J Neurophysiol 118:2194-2215 [Journal] [PubMed]

   Respiratory control model with brainstem CPG and sensory feedback (Diekman, Thomas, and Wilson 2017) [Model]

Fietkiewicz C, Loparo KA, Wilson CG (2011) Drive latencies in hypoglossal motoneurons indicate developmental change in the brainstem respiratory network. J Neural Eng 8:065011 [Journal] [PubMed]

   Bursting respiratory net: clustered architecture gives large phase diff`s (Fietkiewicz et al 2011) [Model]

Harris KD, Dashevskiy T, Mendoza J, Garcia AJ, Ramirez JM, Shea-Brown E (2017) Different roles for inhibition in the rhythm-generating respiratory network. J Neurophysiol 118:2070-2088 [Journal] [PubMed]

   Different roles for inhibition in the rhythm-generating respiratory network (Harris et al 2017) [Model]

Rempe MJ, Best J, Terman D (2010) A mathematical model of the sleep/wake cycle. J Math Biol 60:615-44 [Journal] [PubMed]

   Human sleep/wake cycle (Rempe et al. 2010) [Model]

Wittman S, Abdala AP, Rubin JE (2019) Reduced computational modelling of Kölliker-Fuse contributions to breathing patterns in Rett syndrome. J Physiol 597:2651-2672 [Journal] [PubMed]

   Respiratory central pattern generator including Kolliker-Fuse nucleus (Wittman et al 2019) [Model]

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