Citation Relationships

Dupont G, Lokenye EF, Challiss RA (2011) A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: an unusual mechanism based on repetitive, reversible phosphorylation of the receptor. Biochimie 93:2132-8 [PubMed]

   Glutamate-evoked Ca2+ oscillations in single astrocytes (Modified from Dupont et al. 2011)

References and models cited by this paper

References and models that cite this paper

Atkinson PJ, Young KW, Ennion SJ, Kew JN, Nahorski SR, Challiss RA (2006) Altered expression of G(q/11alpha) protein shapes mGlu1 and mGlu5 receptor-mediated single cell inositol 1,4,5-trisphosphate and Ca(2+) signaling. Mol Pharmacol 69:174-84 [Journal] [PubMed]

Berridge MJ, Lipp P, Bootman MD (2000) The versatility and universality of calcium signalling. Nat Rev Mol Cell Biol 1:11-21 [Journal] [PubMed]

Bezprozvanny I, Watras J, Ehrlich BE (1991) Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature 351:751-4 [Journal] [PubMed]

Bradley SJ, Challiss RA (2011) Defining protein kinase/phosphatase isoenzymic regulation of mGlu5 receptor-stimulated phospholipase C and Ca²? responses in astrocytes. Br J Pharmacol 164:755-71 [Journal] [PubMed]

Bradley SJ, Langmead CJ, Watson JM, Challiss RA (2011) Quantitative analysis reveals multiple mechanisms of allosteric modulation of the mGlu5 receptor in rat astroglia. Mol Pharmacol 79:874-85 [Journal] [PubMed]

Bradley SJ, Watson JM, Challiss RA (2009) Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor. Mol Pharmacol 76:1302-13 [Journal] [PubMed]

Codazzi F, Teruel MN, Meyer T (2001) Control of astrocyte Ca(2+) oscillations and waves by oscillating translocation and activation of protein kinase C. Curr Biol 11:1089-97 [PubMed]

Cuthbertson KS, Chay TR (1991) Modelling receptor-controlled intracellular calcium oscillators. Cell Calcium 12:97-109 [PubMed]

Dale LB, Babwah AV, Bhattacharya M, Kelvin DJ, Ferguson SS (2001) Spatial-temporal patterning of metabotropic glutamate receptor-mediated inositol 1,4,5-triphosphate, calcium, and protein kinase C oscillations: protein kinase C-dependent receptor phosphorylation is not required. J Biol Chem 276:35900-8 [Journal] [PubMed]

De Pittà M, Goldberg M, Volman V, Berry H, Ben-Jacob E (2009) Glutamate regulation of calcium and IP3 oscillating and pulsating dynamics in astrocytes. J Biol Phys 35:383-411 [Journal] [PubMed]

   Glutamate-evoked Ca2+ oscillations in single astrocytes (De Pitta et al. 2009) (Manninen et al 2017) [Model]

Dhami GK, Ferguson SS (2006) Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis. Pharmacol Ther 111:260-71 [Journal] [PubMed]

Dupont G, Combettes L, Bird GS, Putney JW (2011) Calcium oscillations. Cold Spring Harb Perspect Biol [Journal] [PubMed]

Dupont G, Croisier H (2010) Spatiotemporal organization of Ca dynamics: a modeling-based approach. HFSP J 4:43-51 [Journal] [PubMed]

Gallegos LL, Newton AC (2008) Spatiotemporal dynamics of lipid signaling: protein kinase C as a paradigm. IUBMB Life 60:782-9 [Journal] [PubMed]

Goldbeter A, Koshland DE (1981) An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A 78:6840-4 [PubMed]

Haberichter T, Marhl M, Heinrich R (2001) Birhythmicity, trirhythmicity and chaos in bursting calcium oscillations. Biophys Chem 90:17-30 [PubMed]

Hermans E, Challiss RA (2001) Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors. Biochem J 359:465-84 [PubMed]

Kang M, Othmer HG (2007) The variety of cytosolic calcium responses and possible roles of PLC and PKC. Phys Biol 4:325-43 [Journal] [PubMed]

Kang M, Othmer HG (2009) Spatiotemporal characteristics of calcium dynamics in astrocytes. Chaos 19:037116 [Journal] [PubMed]

Kawabata S, Tsutsumi R, Kohara A, Yamaguchi T, Nakanishi S, Okada M (1996) Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors. Nature 383:89-92 [Journal] [PubMed]

Kew JN (2004) Positive and negative allosteric modulation of metabotropic glutamate receptors: emerging therapeutic potential. Pharmacol Ther 104:233-44 [Journal] [PubMed]

Kim CH, Braud S, Isaac JT, Roche KW (2005) Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on Serine 839 regulates Ca2+ oscillations. J Biol Chem 280:25409-15 [Journal] [PubMed]

Kinney GG, Burno M, Campbell UC, Hernandez LM, Rodriguez D, Bristow LJ, Conn PJ (2003) Metabotropic glutamate subtype 5 receptors modulate locomotor activity and sensorimotor gating in rodents. J Pharmacol Exp Ther 306:116-23 [Journal] [PubMed]

Kummer U, Olsen LF, Dixon CJ, Green AK, Bornberg-Bauer E, Baier G (2000) Switching from simple to complex oscillations in calcium signaling. Biophys J 79:1188-95 [Journal] [PubMed]

Lee JH, Lee J, Choi KY, Hepp R, Lee JY, Lim MK, Chatani-Hinze M, Roche PA, Kim DG, Ahn YS, Kim CH, Roche KW (2008) Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5. Proc Natl Acad Sci U S A 105:12575-80 [Journal] [PubMed]

Matsu-ura T, Michikawa T, Inoue T, Miyawaki A, Yoshida M, Mikoshiba K (2006) Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cells. J Cell Biol 173:755-65 [Journal] [PubMed]

McCormick WD, Atkinson-Dell R, Campion KL, Mun HC, Conigrave AD, Ward DT (2010) Increased receptor stimulation elicits differential calcium-sensing receptor(T888) dephosphorylation. J Biol Chem 285:14170-7 [Journal] [PubMed]

Meinke MH, Bishop JS, Edstrom RD (1986) Zero-order ultrasensitivity in the regulation of glycogen phosphorylase. Proc Natl Acad Sci U S A 83:2865-8 [PubMed]

Nash MS, Schell MJ, Atkinson PJ, Johnston NR, Nahorski SR, Challiss RA (2002) Determinants of metabotropic glutamate receptor-5-mediated Ca2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration. J Biol Chem 277:35947-60 [Journal] [PubMed]

Nash MS, Young KW, Challiss RA, Nahorski SR (2001) Intracellular signalling. Receptor-specific messenger oscillations. Nature 413:381-2 [Journal] [PubMed]

Nicoletti F, Bockaert J, Collingridge GL, Conn PJ, Ferraguti F, Schoepp DD, Wroblewski JT, Pin JP (2011) Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology 60:1017-41 [Journal] [PubMed]

Pin JP, Kniazeff J, Goudet C, Bessis AS, Liu J, Galvez T, Acher F, Rondard P, Prézeau L (2004) The activation mechanism of class-C G-protein coupled receptors. Biol Cell 96:335-42 [Journal] [PubMed]

Siekmann I, Wagner LE, Yule D, Fox C, Bryant D, Crampin EJ, Sneyd J (2011) MCMC estimation of Markov models for ion channels. Biophys J 100:1919-29 [Journal] [PubMed]

Sneyd J, Tsaneva-Atanasova K, Reznikov V, Bai Y, Sanderson MJ, Yule DI (2006) A method for determining the dependence of calcium oscillations on inositol trisphosphate oscillations. Proc Natl Acad Sci U S A 103:1675-80 [Journal] [PubMed]

Sneyd J, Tsaneva-Atanasova K, Yule DI, Thompson JL, Shuttleworth TJ (2004) Control of calcium oscillations by membrane fluxes. Proc Natl Acad Sci U S A 101:1392-6 [Journal] [PubMed]

Sorensen SD, Conn PJ (2003) G protein-coupled receptor kinases regulate metabotropic glutamate receptor 5 function and expression. Neuropharmacology 44:699-706 [PubMed]

Spooren WP, Gasparini F, Salt TE, Kuhn R (2001) Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders. Trends Pharmacol Sci 22:331-7 [PubMed]

Thul R, Falcke M (2005) Reactive clusters on a membrane. Phys Biol 2:51-9 [Journal] [PubMed]

Uchino M, Sakai N, Kashiwagi K, Shirai Y, Shinohara Y, Hirose K, Iino M, Yamamura T, Saito N (2004) Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC. J Biol Chem 279:2254-61 [Journal] [PubMed]

Young KW, Nash MS, Challiss RA, Nahorski SR (2003) Role of Ca2+ feedback on single cell inositol 1,4,5-trisphosphate oscillations mediated by G-protein-coupled receptors. J Biol Chem 278:20753-60 [Journal] [PubMed]

Young SH, Wu SV, Rozengurt E (2002) Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C. J Biol Chem 277:46871-6 [Journal] [PubMed]

Manninen T, Havela R, Linne ML (2017) Reproducibility and comparability of computational models for astrocyte calcium excitability Front. Neuroinform. [Journal]

   Ca2+ oscillations in single astrocytes (Lavrentovich and Hemkin 2008) (python) (Manninen et al 2017) [Model]
   Glutamate-evoked Ca2+ oscillations in single astrocytes (Modified from Dupont et al. 2011) [Model]
   Glutamate-evoked Ca2+ oscillations in single astrocytes (De Pitta et al. 2009) (Manninen et al 2017) [Model]
   Reproducibility and comparability of models for astrocyte Ca2+ excitability (Manninen et al 2017) [Model]
   Spontaneous calcium oscillations in single astrocytes (Riera et al. 2011) (Manninen et al 2017) [Model]

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