Citation Relationships

Holmes WR (2000) Models of calmodulin trapping and CaM kinase II activation in a dendritic spine. J Comput Neurosci 8:65-85 [PubMed]

References and models cited by this paper

References and models that cite this paper

Barnes GN, Slevin JT, Vanaman TC (1995) Rat brain protein phosphatase 2A: an enzyme that may regulate autophosphorylated protein kinases. J Neurochem 64:340-53 [PubMed]

Barria A, Muller D, Derkach V, Griffith LC, Soderling TR (1997) Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation. Science 276:2042-5 [PubMed]

Bekkers JM, Stevens CF (1989) NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus. Nature 341:230-3 [Journal] [PubMed]

Bliss TV, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-9 [Journal] [PubMed]

Blitzer RD, Connor JH, Brown GP, Wong T, Shenolikar S, Iyengar R, Landau EM (1998) Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. Science 280:1940-2 [PubMed]

Brickey DA, Bann JG, Fong YL, Perrino L, Brennan RG, Soderling TR (1994) Mutational analysis of the autoinhibitory domain of calmodulin kinase II. J Biol Chem 269:29047-54 [PubMed]

Burger D, Cox JA, Comte M, Stein EA (1984) Sequential conformational changes in calmodulin upon binding of calcium Biochemistry 23:1966-1971

Burger D, Stein EA, Cox JA (1983) Free energy coupling in the interactions between Ca2+, calmodulin, and phosphorylase kinase. J Biol Chem 258:14733-9 [PubMed]

Colbran RJ (1993) Inactivation of Ca2+/calmodulin-dependent protein kinase II by basal autophosphorylation. J Biol Chem 268:7163-70 [PubMed]

Coomber C (1998) Current theories of neuronal information processing performed by Ca2+/calmodulin-dependent protein kinase II with support and insights from computer modelling and simulation. Comput Chem 22:251-63 [PubMed]

Coussens CM, Teyler TJ (1996) Protein kinase and phosphatase activity regulate the form of synaptic plasticity expressed. Synapse 24:97-103 [Journal] [PubMed]

Cox JH, Comte M, Mamar-bachi A, Milos M, Schaer J-J (1988) Cation binding to calmodulin and relation to function Calcium and Calcium Binding Proteins, Gerday C:Gilles R:Bolis L, ed. pp.141

Crouch TH, Klee CB (1980) Positive cooperative binding of calcium to bovine brain calmodulin. Biochemistry 19:3692-8 [PubMed]

Cummings JA, Mulkey RM, Nicoll RA, Malenka RC (1996) Ca2+ signaling requirements for long-term depression in the hippocampus. Neuron 16:825-33 [PubMed]

De Koninck P, Schulman H (1998) Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science 279:227-30 [PubMed]

Desmond NL, Levy WB (1985) Granule cell dendritic spine density in the rat hippocampus varies with spine shape and location. Neurosci Lett 54:219-24 [PubMed]

Dosemeci A, Albers RW (1996) A mechanism for synaptic frequency detection through autophosphorylation of CaM kinase II. Biophys J 70:2493-501 [Journal] [PubMed]

Dosemeci A, Gollop N, Jaffe H (1994) Identification of a major autophosphorylation site on postsynaptic density-associated Ca2+/calmodulin-dependent protein kinase. J Biol Chem 269:31330-3

Frey U, Morris RG (1997) Synaptic tagging and long-term potentiation. Nature 385:533-6 [Journal] [PubMed]

Fukunaga K, Muller D, Miyamoto E (1996) CaM kinase II in long-term potentiation. Neurochem Int 28:343-58 [PubMed]

Fukunaga K, Stoppini L, Miyamoto E, Muller D (1993) Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II. J Biol Chem 268:7863-7 [PubMed]

Gregori L, Gillevet PM, Doan P, Chau V (1985) Mechanism of enzyme regulation by calmodulin and Ca2+. Curr Top Cell Regul 27:447-54 [PubMed]

Hanse E, Gustafsson B (1992) Long-term Potentiation and Field EPSPs in the Lateral and Medial Perforant Paths in the Dentate Gyrus In Vitro: a Comparison. Eur J Neurosci 4:1191-1201 [PubMed]

Hansel C, Artola A, Singer W (1996) Different threshold levels of postsynaptic [Ca2+]i have to be reached to induce LTP and LTD in neocortical pyramidal cells. J Physiol Paris 90:317-9 [PubMed]

Hanson PI, Meyer T, Stryer L, Schulman H (1994) Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals. Neuron 12:943-56 [PubMed]

Hanson PI, Schulman H (1992) Inhibitory autophosphorylation of multifunctional Ca2+/calmodulin-dependent protein kinase analyzed by site-directed mutagenesis. J Biol Chem 267:17216-24 [PubMed]

Hessler NA, Shirke AM, Malinow R (1993) The probability of transmitter release at a mammalian central synapse. Nature 366:569-72 [Journal] [PubMed]

Holmes WR (1990) Is the function of dendritic spines to concentrate calcium? Brain Res 519:338-42 [PubMed]

Holmes WR (1995) Modeling the effect of glutamate diffusion and uptake on NMDA and non-NMDA receptor saturation. Biophys J 69:1734-47 [Journal] [PubMed]

Holmes WR, Levy WB (1990) Insights into associative long-term potentiation from computational models of NMDA receptor-mediated calcium influx and intracellular calcium concentration changes. J Neurophysiol 63:1148-68 [Journal] [PubMed]

Holmes WR, Levy WB (1997) Quantifying the role of inhibition in associative long-term potentiation in dentate granule cells with computational models. J Neurophysiol 78:103-16 [Journal] [PubMed]

Kakiuchi S, Yasuda S, Yamazaki R, Teshima Y, Kanda K, Kakiuchi R, Sobue K (1982) Quantitative determinations of calmodulin in the supernatant and particulate fractions of mammalian tissues. J Biochem 92:1041-8 [PubMed]

Kelly PT, McGuinness TL, Greengard P (1984) Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A 81:945-9 [PubMed]

Kennedy MB, Bennett MK, Erondu NE (1983) Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase. Proc Natl Acad Sci U S A 80:7357-61 [PubMed]

Klee CB (1988) Interaction of calmodulin with Ca2C and target proteins Calmodulin, Cohen P:Klee CB, ed. pp.35

Kretsinger RH (1981) Mechanisms of selective signalling by calcium Neurosci Res Prog Bull 19:213-328

Linse S, Forsén S (1995) Determinants that govern high-affinity calcium binding. Adv Second Messenger Phosphoprotein Res 30:89-151 [PubMed]

Linse S, Helmersson A, Forsén S (1991) Calcium binding to calmodulin and its globular domains. J Biol Chem 266:8050-4 [PubMed]

Lisman J (1989) A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc Natl Acad Sci U S A 86:9574-8 [PubMed]

Lisman J (1994) The CaM kinase II hypothesis for the storage of synaptic memory. Trends Neurosci 17:406-12 [PubMed]

Lisman J, Malenka RC, Nicoll RA, Malinow R (1997) Learning mechanisms: the case for CaM-KII. Science 276:2001-2 [PubMed]

Luby-Phelps K, Hori M, Phelps JM, Won D (1995) Ca(2+)-regulated dynamic compartmentalization of calmodulin in living smooth muscle cells. J Biol Chem 270:21532-8 [PubMed]

Malenka RC (1991) The role of postsynaptic calcium in the induction of long-term potentiation. Mol Neurobiol 5:289-95 [PubMed]

Malenka RC, Nicoll RA (1993) NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms. Trends Neurosci 16:521-7 [PubMed]

Matsushita T, Moriyama S, Fukai T (1995) Switching dynamics and the transient memory storage in a model enzyme network involving Ca2+/calmodulin-dependent protein kinase II in synapses. Biol Cybern 72:497-509 [PubMed]

Mayer ML, Westbrook GL, Guthrie PB (1984) Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones. Nature 309:261-3 [PubMed]

Mayford M, Wang J, Kandel ER, O'Dell TJ (1995) CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell 81:891-904 [PubMed]

Meyer T, Hanson PI, Stryer L, Schulman H (1992) Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science 256:1199-202 [PubMed]

Michelson S, Schulman H (1994) CaM kinase: A model for its activation and dynamics J Theor Biol 171:281-290

Miller SG, Kennedy MB (1986) Regulation of brain type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: a Ca2+-triggered molecular switch. Cell 44:861-70 [PubMed]

Miller SG, Patton BL, Kennedy MB (1988) Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2(+)-independent activity. Neuron 1:593-604 [PubMed]

Mukherji S, Soderling TR (1994) Regulation of Ca2+/calmodulin-dependent protein kinase II by inter- and intrasubunit-catalyzed autophosphorylations. J Biol Chem 269:13744-7 [PubMed]

Ouyang Y, Kantor D, Harris KM, Schuman EM, Kennedy MB (1997) Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus. J Neurosci 17:5416-27 [PubMed]

Patton BL, Miller SG, Kennedy MB (1990) Activation of type II calcium/calmodulin-dependent protein kinase by Ca2+/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain. J Biol Chem 265:11204-12 [PubMed]

Rosenmund C, Clements JD, Westbrook GL (1993) Nonuniform probability of glutamate release at a hippocampal synapse. Science 262:754-7 [PubMed]

Sather W, Dieudonné S, MacDonald JF, Ascher P (1992) Activation and desensitization of N-methyl-D-aspartate receptors in nucleated outside-out patches from mouse neurones. J Physiol 450:643-72 [PubMed]

Schulman H (1993) The multifunctional Ca2+/calmodulin-dependent protein kinases. Curr Opin Cell Biol 5:247-53 [PubMed]

Sharma RK, Mooibroek M, Wang JH (1988) Calmodulin-stimulated cyclic nucleotide phosphodiesterase isozymes Calmodulin, Cohen P:Klee CB, ed. pp.265

Silver RA, Traynelis SF, Cull-Candy SG (1992) Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature 355:163-6 [Journal] [PubMed]

Soderling TR (1993) Calcium/calmodulin-dependent protein kinase II: role in learning and memory. Mol Cell Biochem 127-128:93-101 [PubMed]

Staley KJ, Mody I (1991) Integrity of perforant path fibers and the frequency of action potential independent excitatory and inhibitory synaptic events in dentate gyrus granule cells. Synapse 9:219-24 [Journal] [PubMed]

Stemmer PM, Klee CB (1994) Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. Biochemistry 33:6859-66 [PubMed]

Strack S, Barban MA, Wadzinski BE, Colbran RJ (1997) Differential inactivation of postsynaptic density-associated and soluble Ca2+/calmodulin-dependent protein kinase II by protein phosphatases 1 and 2A. J Neurochem 68:2119-28 [PubMed]

Strack S, Choi S, Lovinger DM, Colbran RJ (1997) Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density. J Biol Chem 272:13467-70 [PubMed]

Stull JT (1988) Myosin light chain kinases and caldesmon: biochemical properties and roles in skeletal and smooth muscle contractions Calmodulin, Cohen P:Klee CB, ed. pp.91

Suzuki T, Okumura-Noji K, Tanaka R, Tada T (1994) Rapid translocation of cytosolic Ca2+/calmodulin-dependent protein kinase II into postsynaptic density after decapitation. J Neurochem 63:1529-37 [PubMed]

Walmsley B, Edwards FR, Tracey DJ (1988) Nonuniform release probabilities underlie quantal synaptic transmission at a mammalian excitatory central synapse. J Neurophysiol 60:889-908 [Journal]

White G, Levy WB, Steward O (1988) Evidence that associative interactions between synapses during the induction of long-term potentiation occur within local dendritic domains. Proc Natl Acad Sci U S A 85:2368-72 [PubMed]

White G, Levy WB, Steward O (1990) Spatial overlap between populations of synapses determines the extent of their associative interaction during the induction of long-term potentiation and depression. J Neurophysiol 64:1186-98 [Journal] [PubMed]

Zador A, Koch C, Brown TH (1990) Biophysical model of a Hebbian synapse. Proc Natl Acad Sci U S A 87:6718-22 [PubMed]

Basak R, Narayanan R (2018) Active dendrites regulate the spatiotemporal spread of signaling microdomains. PLoS Comput Biol 14:e1006485 [Journal] [PubMed]

   Active dendrites shape signaling microdomains in hippocampal neurons (Basak & Narayanan 2018) [Model]

Cornelisse LN, van Elburg RA, Meredith RM, Yuste R, Mansvelder HD (2007) High speed two-photon imaging of calcium dynamics in dendritic spines: consequences for spine calcium kinetics and buffer capacity. PLoS One 2:e1073 [Journal] [PubMed]

   Determinants of fast calcium dynamics in dendritic spines and dendrites (Cornelisse et al. 2007) [Model]

Franks KM, Bartol TM, Sejnowski TJ (2001) An MCell model of calcium dynamics and frequency-dependence of calmodulin activation in dendritic spines Neurocomputing 38:9-16

Graupner M, Brunel N (2007) STDP in a bistable synapse model based on CaMKII and associated signaling pathways. PLoS Comput Biol 3:e221 [Journal] [PubMed]

   CaMKII system exhibiting bistability with respect to calcium (Graupner and Brunel 2007) [Model]

Kim M, Huang T, Abel T, Blackwell KT (2010) Temporal sensitivity of protein kinase a activation in late-phase long term potentiation. PLoS Comput Biol 6:e1000691 [Journal] [PubMed]

   Hippocampus CA1: Temporal sensitivity of signaling pathways underlying LTP (Kim et al. 2010) [Model]

Kubota Y, Bower JM (2001) Transient versus asymptotic dynamics of CaM kinase II: possible roles of phosphatase. J Comput Neurosci 11:263-79 [PubMed]

Manninen T, Hituri K, Kotaleski JH, Blackwell KT, Linne ML (2010) Postsynaptic signal transduction models for long-term potentiation and depression. Front Comput Neurosci 4:152 [Journal] [PubMed]

Miller P, Wang XJ (2006) Stability of discrete memory states to stochastic fluctuations in neuronal systems. Chaos 16:026109 [Journal] [PubMed]

(78 refs)