References and models cited by this paper

References and models that cite this paper

Bhalla US, Iyengar R (1999) Emergent properties of networks of biological signaling pathways. Science 283:381-7 [PubMed]

Bower JM (1990) Reverse engineering the nervous system: an anatomical, physiological, and computer based approach An Introduction to Neural and Electronic Networks, Zornetzer S:Davis J:Lau C, ed. pp.3

Bower JM, Beeman D (1998) The Book Of Genesis: Exploring Realistic Neural Models With The General Neural Simulation System

Braun AP, Schulman H (1995) The multifunctional calcium/calmodulin-dependent protein kinase: from form to function. Annu Rev Physiol 57:417-45

Brocke L, Chiang LW, Wagner PD, Schulman H (1999) Functional implications of the subunit composition of neuronal CaM kinase II. J Biol Chem 274:22713-22 [PubMed]

Brown SE, Martin SR, Bayley PM (1997) Kinetic control of the dissociation pathway of calmodulin-peptide complexes. J Biol Chem 272:3389-97 [PubMed]

Cohen P, Klee CB (1988) Molecular Aspects of Cellular Regulation Calmodulin, Cohen P:Klee CB, ed.

Colbran RJ (1993) Inactivation of Ca2+/calmodulin-dependent protein kinase II by basal autophosphorylation. J Biol Chem 268:7163-70 [PubMed]

Coomber CJ (1998) Site-selective autophosphorylation of Ca2+/calmodulin-dependent protein kinase II as a synaptic encoding mechanism. Neural Comput 10:1653-78 [PubMed]

Crivici A, Ikura M (1995) Molecular and structural basis of target recognition by calmodulin. Annu Rev Biophys Biomol Struct 24:85-116 [Journal] [PubMed]

De Koninck P, Schulman H (1998) Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science 279:227-30 [PubMed]

Dosemeci A, Albers RW (1996) A mechanism for synaptic frequency detection through autophosphorylation of CaM kinase II. Biophys J 70:2493-501 [Journal] [PubMed]

Endo S, Zhou X, Connor J, Wang B, Shenolikar S (1996) Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor. Biochemistry 35:5220-8 [Journal] [PubMed]

Ermentrout GB (1990) PHASEPLANE: The dynamical systems Tool, Version 3.0

Fletcher JE, Spector AA, Ashbrook JD (1970) Analysis of macromolecule--ligand binding by determination of stepwise equilibrium constants. Biochemistry 9:4580-7 [PubMed]

Fong YL, Taylor WL, Means AR, Soderling TR (1989) Studies of the regulatory mechanism of Ca2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate. J Biol Chem 264:16759-63 [PubMed]

Giese KP, Fedorov NB, Filipkowski RK, Silva AJ (1998) Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning. Science 279:870-3 [PubMed]

Hanson PI, Meyer T, Stryer L, Schulman H (1994) Dual role of calmodulin in autophosphorylation of multifunctional CaM kinase may underlie decoding of calcium signals. Neuron 12:943-56 [PubMed]

Hanson PI, Schulman H (1992) Neuronal Ca2+/calmodulin-dependent protein kinases. Annu Rev Biochem 61:559-601 [Journal] [PubMed]

Hashimoto Y, Schworer CM, Colbran RJ, Soderling TR (1987) Autophosphorylation of Ca2+/calmodulin-dependent protein kinase II. Effects on total and Ca2+-independent activities and kinetic parameters. J Biol Chem 262:8051-5 [PubMed]

Holmes WR (2000) Models of calmodulin trapping and CaM kinase II activation in a dendritic spine. J Comput Neurosci 8:65-85 [PubMed]

Husi H, Ward MA, Choudhary JS, Blackstock WP, Grant SG (2000) Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nat Neurosci 3:661-9 [Journal] [PubMed]

Ikeda A, Okuno S, Fujisawa H (1991) Studies on the generation of Ca2+/calmodulin-independent activity of calmodulin-dependent protein kinase II by autophosphorylation. Autothiophosphorylation of the enzyme. J Biol Chem 266:11582-8 [PubMed]

Kanaseki T, Ikeuchi Y, Sugiura H, Yamauchi T (1991) Structural features of Ca2+/calmodulin-dependent protein kinase II revealed by electron microscopy. J Cell Biol 115:1049-60 [PubMed]

Kolb SJ, Hudmon A, Ginsberg TR, Waxham MN (1998) Identification of domains essential for the assembly of calcium/calmodulin-dependent protein kinase II holoenzymes. J Biol Chem 273:31555-64 [PubMed]

Kolodziej SJ, Hudmon A, Waxham MN, Stoops JK (2000) Three-dimensional reconstructions of calcium/calmodulin-dependent (CaM) kinase IIalpha and truncated CaM kinase IIalpha reveal a unique organization for its structural core and functional domains. J Biol Chem 275:14354-9 [PubMed]

Kubota Y, Bower JM (1999) Decoding time-varying calcium signals by the postsynaptic biochemical network: Computer simulation of molecular kinetics Neurocomputing 26:29-38

Leonard AS, Lim IA, Hemsworth DE, Horne MC, Hell JW (1999) Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A 96:3239-44 [PubMed]

Lisman J (1989) A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc Natl Acad Sci U S A 86:9574-8 [PubMed]

Malenka RC, Nicoll RA (1999) Long-term potentiation--a decade of progress? Science 285:1870-4 [PubMed]

Maune JF, Klee CB, Beckingham K (1992) Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin. J Biol Chem 267:5286-95 [PubMed]

Meyer T, Hanson PI, Stryer L, Schulman H (1992) Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science 256:1199-202 [PubMed]

Meyer T, Shen K (2000) In and out of the postsynaptic region: signalling proteins on the move. Trends Cell Biol 10:238-44 [PubMed]

Michelson S, Schulman H (1994) CaM kinase: A model for its activation and dynamics J Theor Biol 171:281-290

Miller SG, Kennedy MB (1986) Regulation of brain type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: a Ca2+-triggered molecular switch. Cell 44:861-70 [PubMed]

Mukherji S, Soderling TR (1994) Regulation of Ca2+/calmodulin-dependent protein kinase II by inter- and intrasubunit-catalyzed autophosphorylations. J Biol Chem 269:13744-7 [PubMed]

Mulkey RM, Endo S, Shenolikar S, Malenka RC (1994) Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature 369:486-8 [Journal] [PubMed]

Okamoto H, Ichikawa K (2000) Switching characteristics of a model for biochemical-reaction networks describing autophosphorylation versus dephosphorylation of Ca2+/calmodulin-dependent protein kinase II. Biol Cybern 82:35-47 [Journal] [PubMed]

Patton BL, Miller SG, Kennedy MB (1990) Activation of type II calcium/calmodulin-dependent protein kinase by Ca2+/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain. J Biol Chem 265:11204-12 [PubMed]

Rich RC, Schulman H (1998) Substrate-directed function of calmodulin in autophosphorylation of Ca2+/calmodulin-dependent protein kinase II. J Biol Chem 273:28424-9 [PubMed]

Shen K, Teruel MN, Connor JH, Shenolikar S, Meyer T (2000) Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II. Nat Neurosci 3:881-6 [Journal] [PubMed]

Strack S, Barban MA, Wadzinski BE, Colbran RJ (1997) Differential inactivation of postsynaptic density-associated and soluble Ca2+/calmodulin-dependent protein kinase II by protein phosphatases 1 and 2A. J Neurochem 68:2119-28 [PubMed]

Strack S, Colbran RJ (1998) Autophosphorylation-dependent targeting of calcium/ calmodulin-dependent protein kinase II by the NR2B subunit of the N-methyl- D-aspartate receptor. J Biol Chem 273:20689-92 [PubMed]

Strack S, McNeill RB, Colbran RJ (2000) Mechanism and regulation of calcium/calmodulin-dependent protein kinase II targeting to the NR2B subunit of the N-methyl-D-aspartate receptor. J Biol Chem 275:23798-806 [Journal] [PubMed]

Walikonis RS, Jensen ON, Mann M, Provance DW, Mercer JA, Kennedy MB (2000) Identification of proteins in the postsynaptic density fraction by mass spectrometry. J Neurosci 20:4069-80 [PubMed]

Zhabotinsky AM (2000) Bistability in the Ca(2+)/calmodulin-dependent protein kinase-phosphatase system. Biophys J 79:2211-21 [Journal] [PubMed]

Gallimore AR, Kim T, Tanaka-Yamamoto K, De Schutter E (2018) Switching On Depression and Potentiation in the Cerebellum. Cell Rep 22:722-733 [Journal] [PubMed]

Graupner M, Brunel N (2007) STDP in a bistable synapse model based on CaMKII and associated signaling pathways. PLoS Comput Biol 3:e221 [Journal] [PubMed]

Kim M, Huang T, Abel T, Blackwell KT (2010) Temporal sensitivity of protein kinase a activation in late-phase long term potentiation. PLoS Comput Biol 6:e1000691 [Journal] [PubMed]

Lindskog M, Kim M, Wikström MA, Blackwell KT, Kotaleski JH (2006) Transient calcium and dopamine increase PKA activity and DARPP-32 phosphorylation. PLoS Comput Biol 2:e119 [Journal] [PubMed]

Manninen T, Hituri K, Kotaleski JH, Blackwell KT, Linne ML (2010) Postsynaptic signal transduction models for long-term potentiation and depression. Front Comput Neurosci 4:152 [Journal] [PubMed]

Zamora Chimal CG, De Schutter E (2018) Ca2+ Requirements for Long-Term Depression Are Frequency Sensitive in Purkinje Cells. Front Mol Neurosci 11:438 [Journal] [PubMed]