Citation Relationships

Chen N, Li B, Murphy TH, Raymond LA (2004) Site within N-Methyl-D-aspartate receptor pore modulates channel gating. Mol Pharmacol 65:157-64 [PubMed]

References and models cited by this paper

References and models that cite this paper

Antonov SM, Johnson JW (1996) Voltage-dependent interaction of open-channel blocking molecules with gating of NMDA receptors in rat cortical neurons. J Physiol 493 ( Pt 2):425-45 [PubMed]

Beck C, Wollmuth LP, Seeburg PH, Sakmann B, Kuner T (1999) NMDAR channel segments forming the extracellular vestibule inferred from the accessibility of substituted cysteines. Neuron 22:559-70 [PubMed]

Béhé P, Stern P, Wyllie DJ, Nassar M, Schoepfer R, Colquhoun D (1995) Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors. Proc Biol Sci 262:205-13 [Journal] [PubMed]

Buck DP, Howitt SM, Clements JD (2000) NMDA channel gating is influenced by a tryptophan residue in the M2 domain but calcium permeation is not altered. Biophys J 79:2454-62 [Journal] [PubMed]

Burnashev N (1996) Calcium permeability of glutamate-gated channels in the central nervous system. Curr Opin Neurobiol 6:311-7 [PubMed]

Burnashev N, Schoepfer R, Monyer H, Ruppersberg JP, Günther W, Seeburg PH, Sakmann B (1992) Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. Science 257:1415-9 [PubMed]

Chen N, Moshaver A, Raymond LA (1997) Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition. Mol Pharmacol 51:1015-23 [PubMed]

Chen N, Ren J, Raymond LA, Murphy TH (2001) Changes in agonist concentration dependence that are a function of duration of exposure suggest N-methyl-D-aspartate receptor nonsaturation during synaptic stimulation. Mol Pharmacol 59:212-9 [Journal] [PubMed]

   NMDA receptor saturation (Chen et al 2001) [Model]

Clements JD, Westbrook GL (1991) Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor. Neuron 7:605-13 [PubMed]

Colquhoun D (1998) Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors. Br J Pharmacol 125:924-47 [PubMed]

Destexhe A, Mainen ZF, Sejnowski TJ (1998) Kinetic models of synaptic transmission Methods In Neuronal Modeling, Koch C:Segev I, ed. pp.1

   Kinetic synaptic models applicable to building networks (Destexhe et al 1998) [Model]

Dingledine R, Borges K, Bowie D, Traynelis SF (1999) The glutamate receptor ion channels. Pharmacol Rev 51:7-61 [PubMed]

Hessler NA, Shirke AM, Malinow R (1993) The probability of transmitter release at a mammalian central synapse. Nature 366:569-72 [Journal] [PubMed]

Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-209 [PubMed]

Jones KS, VanDongen HM, VanDongen AM (2002) The NMDA receptor M3 segment is a conserved transduction element coupling ligand binding to channel opening. J Neurosci 22:2044-53 [PubMed]

Kashiwagi K, Pahk AJ, Masuko T, Igarashi K, Williams K (1997) Block and modulation of N-methyl-D-aspartate receptors by polyamines and protons: role of amino acid residues in the transmembrane and pore-forming regions of NR1 and NR2 subunits. Mol Pharmacol 52:701-13 [PubMed]

Kiss L, Korn SJ (1998) Modulation of C-type inactivation by K+ at the potassium channel selectivity filter. Biophys J 74:1840-9 [Journal] [PubMed]

Kohda K, Wang Y, Yuzaki M (2000) Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties. Nat Neurosci 3:315-22 [Journal] [PubMed]

Krupp JJ, Vissel B, Heinemann SF, Westbrook GL (1998) N-terminal domains in the NR2 subunit control desensitization of NMDA receptors. Neuron 20:317-27 [PubMed]

Kuner T, Wollmuth LP, Karlin A, Seeburg PH, Sakmann B (1996) Structure of the NMDA receptor channel M2 segment inferred from the accessibility of substituted cysteines. Neuron 17:343-52 [PubMed]

Low CM, Lyuboslavsky P, French A, Le P, Wyatte K, Thiel WH, Marchan EM, Igarashi K, Kashiwagi K, Gernert K, Williams K, Traynelis SF, Zheng F (2003) Molecular determinants of proton-sensitive N-methyl-D-aspartate receptor gating. Mol Pharmacol 63:1212-22 [Journal] [PubMed]

MacKinnon R (1995) Pore loops: an emerging theme in ion channel structure. Neuron 14:889-92 [PubMed]

McBain CJ, Mayer ML (1994) N-methyl-D-aspartic acid receptor structure and function. Physiol Rev 74:723-60 [Journal] [PubMed]

Molina A, Ortega-Sáenz P, Lopez-Barneo J (1998) Pore mutations alter closing and opening kinetics in Shaker K+ channels. J Physiol 509 ( Pt 2):327-37 [PubMed]

Mori H, Masaki H, Yamakura T, Mishina M (1992) Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channel. Nature 358:673-5 [Journal] [PubMed]

Premkumar LS, Auerbach A (1996) Identification of a high affinity divalent cation binding site near the entrance of the NMDA receptor channel. Neuron 16:869-80 [PubMed]

Rasmusson RL, Morales MJ, Wang S, Liu S, Campbell DL, Brahmajothi MV, Strauss HC (1998) Inactivation of voltage-gated cardiac K+ channels. Circ Res 82:739-50 [PubMed]

Raymond LA, Moshaver A, Tingley WG, Huganir RL (1996) Glutamate receptor ion channel properties predict vulnerability to cytotoxicity in a transfected nonneuronal cell line. Mol Cell Neurosci 7:102-15 [PubMed]

Sakurada K, Masu M, Nakanishi S (1993) Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor. J Biol Chem 268:410-5 [PubMed]

Schneggenburger R, Ascher P (1997) Coupling of permeation and gating in an NMDA-channel pore mutant. Neuron 18:167-77 [PubMed]

Sobolevsky AI, Beck C, Wollmuth LP (2002) Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating. Neuron 33:75-85 [PubMed]

Sobolevsky AI, Koshelev SG, Khodorov BI (1999) Probing of NMDA channels with fast blockers. J Neurosci 19:10611-26 [PubMed]

Stern-Bach Y, Bettler B, Hartley M, Sheppard PO, O'Hara PJ, Heinemann SF (1994) Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron 13:1345-57 [PubMed]

Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E (2002) Mechanism of glutamate receptor desensitization. Nature 417:245-53 [Journal] [PubMed]

Sun ZP, Akabas MH, Goulding EH, Karlin A, Siegelbaum SA (1996) Exposure of residues in the cyclic nucleotide-gated channel pore: P region structure and function in gating. Neuron 16:141-9 [PubMed]

Villarroel A, Regalado MP, Lerma J (1998) Glycine-independent NMDA receptor desensitization: localization of structural determinants. Neuron 20:329-39 [PubMed]

Wo ZG, Oswald RE (1995) Unraveling the modular design of glutamate-gated ion channels. Trends Neurosci 18:161-8 [PubMed]

Wollmuth LP, Kuner T, Seeburg PH, Sakmann B (1996) Differential contribution of the NR1- and NR2A-subunits to the selectivity filter of recombinant NMDA receptor channels. J Physiol 491 ( Pt 3):779-97 [PubMed]

Wood MW, VanDongen HM, VanDongen AM (1995) Structural conservation of ion conduction pathways in K channels and glutamate receptors. Proc Natl Acad Sci U S A 92:4882-6 [PubMed]

Zheng F, Erreger K, Low CM, Banke T, Lee CJ, Conn PJ, Traynelis SF (2001) Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A. Nat Neurosci 4:894-901 [Journal] [PubMed]

Carnevale NT, Morse TM (1996-2009) Research reports that have used NEURON Web published citations at the NEURON website [Journal]

(41 refs)