References and models cited by this paper

References and models that cite this paper

Abeles M (1982) Role of the cortical neuron: integrator or coincidence detector? Isr J Med Sci 18:83-92 [PubMed]

Agrawal N, Hamam BN, Magistretti J, Alonso A, Ragsdale DS (2001) Persistent sodium channel activity mediates subthreshold membrane potential oscillations and low-threshold spikes in rat entorhinal cortex layer V neurons. Neuroscience 102:53-64 [PubMed]

Axmacher N, Miles R (2004) Intrinsic cellular currents and the temporal precision of EPSP-action potential coupling in CA1 pyramidal cells. J Physiol 555:713-25 [Journal] [PubMed]

Barry PH, Lynch JW (1991) Liquid junction potentials and small cell effects in patch-clamp analysis. J Membr Biol 121:101-17 [PubMed]

Chéry N, de Koninck Y (1999) Junctional versus extrajunctional glycine and GABA(A) receptor-mediated IPSCs in identified lamina I neurons of the adult rat spinal cord. J Neurosci 19:7342-55 [PubMed]

Chéry N, Yu XH, de Koninck Y (2000) Visualization of lamina I of the dorsal horn in live adult rat spinal cord slices. J Neurosci Methods 96:133-42 [PubMed]

Connors BW, Gutnick MJ (1990) Intrinsic firing patterns of diverse neocortical neurons. Trends Neurosci 13:99-104 [PubMed]

Coull JA, Boudreau D, Bachand K, Prescott SA, Nault F, Sík A, De Koninck P, De Koninck Y (2003) Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain. Nature 424:938-42 [Journal] [PubMed]

Craig AD (1994) Spinal and supraspinal processing of specific pain andtemperature Touch, temperature, and pain in health and disease, Bovie J:Hannson P:Lindblom U, ed. pp.421

Craig AD (2000) The functional anatomy of lamina I and its role in post-stroke central pain. Prog Brain Res 129:137-51 [Journal] [PubMed]

Crill WE (1996) Persistent sodium current in mammalian central neurons. Annu Rev Physiol 58:349-62 [Journal] [PubMed]

Crill WE (2003) Functional implications of dendritic voltage-dependent conductances. J Physiol Paris 93:17-21

Crill WE, Schwindt PC, Oakley JC (2002) Enhanced transmission of glutamate current flowing from the dendrite to the soma in rat neocortical layer 5 neurons. Novartis Found Symp 241:61-8; discussion 68-71, 226-32 [PubMed]

Deisz RA, Fortin G, Zieglgänsberger W (1991) Voltage dependence of excitatory postsynaptic potentials of rat neocortical neurons. J Neurophysiol 65:371-82 [Journal] [PubMed]

Derjean D, Bertrand S, Le Masson G, Landry M, Morisset V, Nagy F (2003) Dynamic balance of metabotropic inputs causes dorsal horn neurons to switch functional states. Nat Neurosci 6:274-81 [Journal] [PubMed]

Destexhe A, Contreras D, Sejnowski TJ, Steriade M (1994) A model of spindle rhythmicity in the isolated thalamic reticular nucleus. J Neurophysiol 72:803-18 [Journal] [PubMed]

Dodt HU, Frick A, Kampe K, Zieglgänsberger W (1998) NMDA and AMPA receptors on neocortical neurons are differentially distributed. Eur J Neurosci 10:3351-7 [PubMed]

Fleidervish IA, Gutnick MJ (1996) Kinetics of slow inactivation of persistent sodium current in layer V neurons of mouse neocortical slices. J Neurophysiol 76:2125-30 [Journal] [PubMed]

Fricker D, Miles R (2000) EPSP amplification and the precision of spike timing in hippocampal neurons. Neuron 28:559-69 [PubMed]

Furue H, Narikawa K, Kumamoto E, Yoshimura M (1999) Responsiveness of rat substantia gelatinosa neurones to mechanical but not thermal stimuli revealed by in vivo patch-clamp recording. J Physiol 521 Pt 2:529-35 [PubMed]

Geijo-Barrientos E (2000) Subthreshold inward membrane currents in guinea-pig frontal cortex neurons. Neuroscience 95:965-72 [PubMed]

Gillessen T, Alzheimer C (1997) Amplification of EPSPs by low Ni(2+)- and amiloride-sensitive Ca2+ channels in apical dendrites of rat CA1 pyramidal neurons. J Neurophysiol 77:1639-43 [Journal] [PubMed]

González-Burgos G, Barrionuevo G (2001) Voltage-gated sodium channels shape subthreshold EPSPs in layer 5 pyramidal neurons from rat prefrontal cortex. J Neurophysiol 86:1671-84 [Journal] [PubMed]

Grudt TJ, Perl ER (2002) Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn. J Physiol 540:189-207 [PubMed]

Heinke B, Balzer E, Sandkühler J (2004) Pre- and postsynaptic contributions of voltage-dependent Ca2+ channels to nociceptive transmission in rat spinal lamina I neurons. Eur J Neurosci 19:103-11 [PubMed]

Herzog RI, Cummins TR, Waxman SG (2001) Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. J Neurophysiol 86:1351-64 [Journal] [PubMed]

Higure Y, Katayama Y, Takeuchi K, Ohtubo Y, Yoshii K (2003) Lucifer Yellow slows voltage-gated Na+ current inactivation in a light-dependent manner in mice. J Physiol 550:159-67 [Journal] [PubMed]

Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-209 [PubMed]

Ikeda H, Heinke B, Ruscheweyh R, Sandkühler J (2003) Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia. Science 299:1237-40 [Journal] [PubMed]

Jo YH, Stoeckel ME, Schlichter R (1998) Electrophysiological properties of cultured neonatal rat dorsal horn neurons containing GABA and met-enkephalin-like immunoreactivity. J Neurophysiol 79:1583-6 [Journal] [PubMed]

Kay AR, Wong RK (1987) Calcium current activation kinetics in isolated pyramidal neurones of the Ca1 region of the mature guinea-pig hippocampus. J Physiol 392:603-16 [PubMed]

König P, Engel AK, Singer W (1996) Integrator or coincidence detector? The role of the cortical neuron revisited. Trends Neurosci 19:130-7 [PubMed]

Lee JH, Gomora JC, Cribbs LL, Perez-Reyes E (1999) Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H. Biophys J 77:3034-42 [Journal] [PubMed]

Lee RH, Heckman CJ (2001) Essential role of a fast persistent inward current in action potential initiation and control of rhythmic firing. J Neurophysiol 85:472-5 [Journal] [PubMed]

Light AR (1992) The initial processing of pain and its descending control:spinal and trigeminal systems

Lipowsky R, Gillessen T, Alzheimer C (1996) Dendritic Na+ channels amplify EPSPs in hippocampal CA1 pyramidal cells. J Neurophysiol 76:2181-91 [Journal] [PubMed]

Llinás RR (1988) The intrinsic electrophysiological properties of mammalian neurons: insights into central nervous system function. Science 242:1654-64 [PubMed]

Lopez-Garcia JA, King AE (1994) Membrane properties of physiologically classified rat dorsal horn neurons in vitro: correlation with cutaneous sensory afferent input. Eur J Neurosci 6:998-1007 [PubMed]

Magee JC (2000) Dendritic integration of excitatory synaptic input. Nat Rev Neurosci 1:181-90 [Journal] [PubMed]

Magee JC, Carruth M (1999) Dendritic voltage-gated ion channels regulate the action potential firing mode of hippocampal CA1 pyramidal neurons. J Neurophysiol 82:1895-901 [Journal] [PubMed]

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ (1995) A model of spike initiation in neocortical pyramidal neurons. Neuron 15:1427-39 [PubMed]

Morisset V, Nagy F (1998) Nociceptive integration in the rat spinal cord: role of non-linear membrane properties of deep dorsal horn neurons. Eur J Neurosci 10:3642-52 [PubMed]

Morisset V, Nagy F (1999) Ionic basis for plateau potentials in deep dorsal horn neurons of the rat spinal cord. J Neurosci 19:7309-16 [PubMed]

Paternain AV, Morales M, Lerma J (1995) Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons. Neuron 14:185-9 [PubMed]

Perl ER (1984) Pain and nociception Sensory processes, Darian-Smith I, ed. pp.915

Pouille F, Scanziani M (2001) Enforcement of temporal fidelity in pyramidal cells by somatic feed-forward inhibition. Science 293:1159-63 [Journal] [PubMed]

Prescott SA, De Koninck Y (2002) Four cell types with distinctive membrane properties and morphologies in lamina I of the spinal dorsal horn of the adult rat. J Physiol 539:817-36 [PubMed]

Rudolph M, Destexhe A (2003) Tuning neocortical pyramidal neurons between integrators and coincidence detectors. J Comput Neurosci 14:239-51 [PubMed]

Ruscheweyh R, Ikeda H, Heinke B, Sandkühler J (2004) Distinctive membrane and discharge properties of rat spinal lamina I projection neurones in vitro. J Physiol 555:527-43 [Journal] [PubMed]

Ruscheweyh R, Sandkühler J (2002) Lamina-specific membrane and discharge properties of rat spinal dorsal horn neurones in vitro. J Physiol 541:231-44 [PubMed]

Russo RE, Hounsgaard J (1999) Dynamics of intrinsic electrophysiological properties in spinal cord neurones. Prog Biophys Mol Biol 72:329-65 [PubMed]

Safronov BV (1999) Spatial distribution of NA+ and K+ channels in spinal dorsal horn neurones: role of the soma, axon and dendrites in spike generation. Prog Neurobiol 59:217-41 [PubMed]

Safronov BV, Wolff M, Vogel W (1997) Functional distribution of three types of Na+ channel on soma and processes of dorsal horn neurones of rat spinal cord. J Physiol 503 ( Pt 2):371-85 [PubMed]

Schneider SP (2003) Spike frequency adaptation and signaling properties of identified neurons in rodent deep spinal dorsal horn. J Neurophysiol 90:245-58 [Journal] [PubMed]

Schwindt PC, Spain WJ, Crill WE (1992) Effects of intracellular calcium chelation on voltage-dependent and calcium-dependent currents in cat neocortical neurons. Neuroscience 47:571-8 [PubMed]

Staley KJ, Otis TS, Mody I (1992) Membrane properties of dentate gyrus granule cells: comparison of sharp microelectrode and whole-cell recordings. J Neurophysiol 67:1346-58 [Journal] [PubMed]

Stuart G, Sakmann B (1995) Amplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons. Neuron 15:1065-76 [PubMed]

Thomson AM, West DC, Headley PM (1989) Membrane Characteristics and Synaptic Responsiveness of Superficial Dorsal Horn Neurons in a Slice Preparation of Adult Rat Spinal Cord. Eur J Neurosci 1:479-488 [PubMed]

Traub RD, Miles R (1991) Neuronal Networks Of The Hippocampus

Urban NN, Henze DA, Barrionuevo G (1998) Amplification of perforant-path EPSPs in CA3 pyramidal cells by LVA calcium and sodium channels. J Neurophysiol 80:1558-61 [Journal] [PubMed]

Willis WD (1985) The pain system. The neural basis of nociceptive transmission in the mammalian nervous system. Pain Headache 8:1-346 [PubMed]

Yoshimura M, Jessell TM (1989) Membrane properties of rat substantia gelatinosa neurons in vitro. J Neurophysiol 62:109-18 [Journal] [PubMed]

Zhang L, Weiner JL, Valiante TA, Velumian AA, Watson PL, Jahromi SS, Schertzer S, Pennefather P, Carlen PL (1994) Whole-cell recording of the Ca(2+)-dependent slow afterhyperpolarization in hippocampal neurones: effects of internally applied anions. Pflugers Arch 426:247-53 [PubMed]

Aguiar P, Sousa M, Lima D (2010) NMDA channels together with L-type calcium currents and calcium-activated nonspecific cationic currents are sufficient to generate windup in WDR neurons. J Neurophysiol 104:1155-66 [Journal] [PubMed]

Balachandar A, Prescott SA (2018) Origin of heterogeneous spiking patterns from continuously distributed ion channel densities: a computational study in spinal dorsal horn neurons. J Physiol 596:1681-1697 [Journal] [PubMed]

Brette R, Rudolph M, Carnevale T, Hines M, Beeman D, Bower JM, Diesmann M, Morrison A, Goodman PH, Harris FC, Zirpe M, Natschläger T, Pecevski D, Ermentrout B, Djurfeldt M, Lansner A, Rochel O, Vieville T, Muller E, Davison AP, El Boustani S, Destexhe A (2007) Simulation of networks of spiking neurons: a review of tools and strategies. J Comput Neurosci 23:349-98 [Journal] [PubMed]

Kuo JJ, Lee RH, Zhang L, Heckman CJ (2006) Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones. J Physiol 574:819-34 [Journal] [PubMed]

Prescott SA, De Koninck Y, Sejnowski TJ (2008) Biophysical basis for three distinct dynamical mechanisms of action potential initiation. PLoS Comput Biol 4:e1000198 [Journal] [PubMed]

Prescott SA, Sejnowski TJ, De Koninck Y (2006) Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain. Mol Pain 2:32 [Journal] [PubMed]

Zhang TC, Janik JJ, Grill WM (2014) Modeling effects of spinal cord stimulation on wide-dynamic range dorsal horn neurons: influence of stimulation frequency and GABAergic inhibition. J Neurophysiol 112:552-67 [Journal] [PubMed]