"Intracellular recordings of neuronal membrane potential are a central tool in neurophysiology.
We introduce a computer-aided technique, Active Electrode Compensation (AEC), based on a digital model of the electrode interfaced in real time with the electrophysiological setup.
AEC should be particularly useful to characterize fast neuronal phenomena intracellularly in vivo."
Brette R, Piwkowska Z, Monier C, Rudolph-Lilith M, Fournier J, Levy M, Fregnac Y, Bal T, Dest (2008) High-resolution intracellular recordings using a real-time computational model of the electrode. Neuron 59:379-91 [PubMed]