Advanced search
SenseLab
SimToolDB
ModelDB Help
User account
Login
Register
Find models by
Model name
First author
Each author
Region(circuits)
Find models for
Cell type
Current
Receptor
Gene
Transmitters
Concept
Simulators
Methods
Find models of
Realistic Networks
Neurons
Electrical synapses (gap junctions)
Chemical synapses
Ion channels
Neuromuscular junctions
Axons
Pathophysiology
Other resources
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
High frequency oscillations induced in three gap-junction coupled neurons (Tseng et al. 2008)
 
Download zip file
Help downloading and running models
Model Information
Model File
Citations
Model Views
Simulation Platform
Accession:
114735
Here we showed experimentally that high frequency oscillations (up to 600 Hz) were easily induced in a purely gap-junction coupled network by simple two stimuli with very short interval. The root cause is that the second elicited spike suffered from slow propagation speed and failure to transmit through a low-conductance junction. Similiar results were also obtained in these simulation.
Reference:
1 .
Tseng SH, Tsai LY, Yeh SR (2008) Induction of high-frequency oscillations in a junction-coupled network.
J Neurosci
28
:7165-73
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Axon;
Brain Region(s)/Organism:
Cell Type(s):
Hodgkin-Huxley neuron;
Channel(s):
Gap Junctions:
Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Action Potential Initiation;
Axonal Action Potentials;
Action Potentials;
Delay;
Conduction failure;
Implementer(s):
Tseng, Shin-Hua ;
Download the displayed file
/
HFO
ReadMe.html
gap.mod
HFO_model.hoc
mosinit.hoc
screenshot.jpg
simulation.ses
slide.jpg
Load Model View
Loading data, please wait...