"Spike-timing dependent plasticity (STDP) is a form of associative synaptic modification which depends
on the respective timing of pre- and post-synaptic spikes.
The biophysical mechanisms underlying this
form of plasticity are currently not known.
We present here a biophysical model which captures the
characteristics of STDP, such as its frequency dependency, and the effects of spike pair or spike triplet
A simplified phenomenological
model is also derived..."
Badoual M, Zou Q, Davison AP, Rudolph M, Bal T, Fregnac Y, Destexhe A (2006) Biophysical and phenomenological models of multiple spike interactions in spike-timing dependent plasticity. Int J Neural Syst 16:79-97 [PubMed]