Synaptic plasticity can produce and enhance direction selectivity (Carver et al, 2008)

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Accession:116901
" ... We propose a parsimonious model of motion processing that generates direction selective responses using short-term synaptic depression and can reproduce salient features of direction selectivity found in a population of neurons in the midbrain of the weakly electric fish Eigenmannia virescens. The model achieves direction selectivity with an elementary Reichardt motion detector: information from spatially separated receptive fields converges onto a neuron via dynamically different pathways. In the model, these differences arise from convergence of information through distinct synapses that either exhibit or do not exhibit short-term synaptic depression—short-term depression produces phase-advances relative to nondepressing synapses. ..."
Reference:
1 . Carver S, Roth E, Cowan NJ, Fortune ES (2008) Synaptic plasticity can produce and enhance direction selectivity. PLoS Comput Biol 4:e32 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Electric fish midbrain torus semicircularis neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Oscillations; Depression; Direction Selectivity; Synaptic Convergence;
Implementer(s): Carver, Sean [sean.carver at jhu.edu];
 
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