Permeation and inactivation of CaV1.2 Ca2+ channels (Babich et al. 2007)


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Accession:118759
The authors present data and a kinetics model of the CaV1.2 channel supporting the idea that Ca2+ block of the pore generates the U-shaped inactivation curve.
Reference:
1 . Babich O, Matveev V, Harris AL, Shirokov R (2007) Ca2+-dependent inactivation of CaV1.2 channels prevents Gd3+ block: does Ca2+ block the pore of inactivated channels? J Gen Physiol 129:477-83 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Channel/Receptor;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): I L high threshold;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: CalC Calcium Calculator (web link to model);
Model Concept(s): Ion Channel Kinetics;
Implementer(s):
Search NeuronDB for information about:  I L high threshold;
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