Global structure, robustness, and modulation of neuronal models (Goldman et al. 2001)

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"The electrical characteristics of many neurons are remarkably robust in the face of changing internal and external conditions. At the same time, neurons can be highly sensitive to neuromodulators. We find correlates of this dual robustness and sensitivity in a global analysis of the structure of a conductance-based model neuron. ..."
1 . Goldman MS, Golowasch J, Marder E, Abbott LF (2001) Global structure, robustness, and modulation of neuronal models. J Neurosci 21:5229-38 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Stomatogastric ganglion;
Cell Type(s):
Channel(s): I Na,t; I L high threshold; I T low threshold; I A; I K; I K,Ca; I Potassium;
Gap Junctions:
Simulation Environment: C or C++ program;
Model Concept(s): Bursting; Temporal Pattern Generation; Phase Response Curves;
Implementer(s): Goldman, Mark [msgoldman at];
Search NeuronDB for information about:  I Na,t; I L high threshold; I T low threshold; I A; I K; I K,Ca; I Potassium;
// RunPage.h : header file

// CRunPage dialog

class CRunPage : public CPropertyPage

// Construction

// Attributes
	BOOL m_bChangeMade; //TRUE when apply button enabled
	BOOL m_bPaused; //true if user hits pause button
	double m_MaxInj_arr[_MAX_COMPARTS][_MAX_INJ_TIMES]; //array of injections into each compartment
// cell controls
	CButton& ctrlRunButt() { return *(CButton *) GetDlgItem (IDC_RUN_BUTTON); }
	CButton& ctrlPauseButt() { return *(CButton *) GetDlgItem (IDC_PAUSE_BUTTON); }
	CButton& ctrlEndButt() { return *(CButton *) GetDlgItem (IDC_END_RUN_BUTTON); }
	CButton& ctrlApplyButt() { return *(CButton *) GetDlgItem (IDC_APPLY_BUTT); }

// Dialog Data
	enum { IDD = IDD_RUNPAGE };
	double	m_tmax;
	double	m_InjOffTime;
	double	m_InjOnTime;
	double	m_InjOnTime2;
	int		m_SaveFlag;
	int		m_DisplayFlag;
	double	m_MaxInjSoma;
	double	m_MaxInjSoma2;
	double	m_MaxInjHillock;
	double	m_MaxInjHillock2;
	double	m_dtmax;
	double	m_dtmin;

// Overrides
	// ClassWizard generate virtual function overrides
	virtual void DoDataExchange(CDataExchange* pDX);    // DDX/DDV support
	virtual BOOL OnCommand(WPARAM wParam, LPARAM lParam);
	void Serialize(CArchive& ar);

// Implementation
	// Generated message map functions
	afx_msg void OnRunButton();
	afx_msg void OnEndRunButton();
	afx_msg void OnPauseButton();
	afx_msg void OnApplyButt();
	virtual BOOL OnInitDialog();


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