Global structure, robustness, and modulation of neuronal models (Goldman et al. 2001)

 Download zip file 
Help downloading and running models
Accession:127878
"The electrical characteristics of many neurons are remarkably robust in the face of changing internal and external conditions. At the same time, neurons can be highly sensitive to neuromodulators. We find correlates of this dual robustness and sensitivity in a global analysis of the structure of a conductance-based model neuron. ..."
Reference:
1 . Goldman MS, Golowasch J, Marder E, Abbott LF (2001) Global structure, robustness, and modulation of neuronal models. J Neurosci 21:5229-38 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Stomatogastric ganglion;
Cell Type(s):
Channel(s): I Na,t; I L high threshold; I T low threshold; I A; I K; I K,Ca; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: C or C++ program;
Model Concept(s): Bursting; Temporal Pattern Generation; Phase Response Curves;
Implementer(s): Goldman, Mark [msgoldman at ucdavis.edu];
Search NeuronDB for information about:  I Na,t; I L high threshold; I T low threshold; I A; I K; I K,Ca; I Potassium;
# Microsoft Developer Studio Project File - Name="ZhengModel" - Package Owner=<4>
# Microsoft Developer Studio Generated Build File, Format Version 5.00
# ** DO NOT EDIT **

# TARGTYPE "Win32 (x86) Application" 0x0101

CFG=ZhengModel - Win32 Release
!MESSAGE This is not a valid makefile. To build this project using NMAKE,
!MESSAGE use the Export Makefile command and run
!MESSAGE 
!MESSAGE NMAKE /f "ZhengModel.mak".
!MESSAGE 
!MESSAGE You can specify a configuration when running NMAKE
!MESSAGE by defining the macro CFG on the command line. For example:
!MESSAGE 
!MESSAGE NMAKE /f "ZhengModel.mak" CFG="ZhengModel - Win32 Release"
!MESSAGE 
!MESSAGE Possible choices for configuration are:
!MESSAGE 
!MESSAGE "ZhengModel - Win32 Release" (based on "Win32 (x86) Application")
!MESSAGE "ZhengModel - Win32 Debug" (based on "Win32 (x86) Application")
!MESSAGE 

# Begin Project
# PROP Scc_ProjName ""
# PROP Scc_LocalPath ""
CPP=cl.exe
MTL=midl.exe
RSC=rc.exe

!IF  "$(CFG)" == "ZhengModel - Win32 Release"

# PROP BASE Use_MFC 6
# PROP BASE Use_Debug_Libraries 0
# PROP BASE Output_Dir ".\Release"
# PROP BASE Intermediate_Dir ".\Release"
# PROP BASE Target_Dir ""
# PROP Use_MFC 6
# PROP Use_Debug_Libraries 0
# PROP Output_Dir ".\Release"
# PROP Intermediate_Dir ".\Release"
# PROP Target_Dir ""
# ADD BASE CPP /nologo /MD /W3 /GX /O2 /D "WIN32" /D "NDEBUG" /D "_WINDOWS" /D "_AFXDLL" /D "_MBCS" /Yu"stdafx.h" /c
# ADD CPP /nologo /G5 /MD /W3 /GX /D "WIN32" /D "NDEBUG" /D "_WINDOWS" /D "_AFXDLL" /D "_MBCS" /Yu"stdafx.h" /FD /c
# ADD BASE MTL /nologo /D "NDEBUG" /win32
# ADD MTL /nologo /D "NDEBUG" /mktyplib203 /win32
# ADD BASE RSC /l 0x409 /d "NDEBUG" /d "_AFXDLL"
# ADD RSC /l 0x409 /d "NDEBUG" /d "_AFXDLL"
BSC32=bscmake.exe
# ADD BASE BSC32 /nologo
# ADD BSC32 /nologo
LINK32=link.exe
# ADD BASE LINK32 /nologo /subsystem:windows /machine:I386
# ADD LINK32 /nologo /subsystem:windows /machine:I386

!ELSEIF  "$(CFG)" == "ZhengModel - Win32 Debug"

# PROP BASE Use_MFC 6
# PROP BASE Use_Debug_Libraries 1
# PROP BASE Output_Dir ".\Debug"
# PROP BASE Intermediate_Dir ".\Debug"
# PROP BASE Target_Dir ""
# PROP Use_MFC 6
# PROP Use_Debug_Libraries 1
# PROP Output_Dir ".\Debug"
# PROP Intermediate_Dir ".\Debug"
# PROP Ignore_Export_Lib 0
# PROP Target_Dir ""
# ADD BASE CPP /nologo /MDd /W3 /Gm /GX /Zi /Od /D "WIN32" /D "_DEBUG" /D "_WINDOWS" /D "_AFXDLL" /D "_MBCS" /Yu"stdafx.h" /c
# ADD CPP /nologo /G5 /MDd /W3 /Gm /GX /Zi /Od /D "WIN32" /D "_DEBUG" /D "_WINDOWS" /D "_AFXDLL" /D "_MBCS" /Yu"stdafx.h" /FD /c
# ADD BASE MTL /nologo /D "_DEBUG" /win32
# ADD MTL /nologo /D "_DEBUG" /mktyplib203 /win32
# ADD BASE RSC /l 0x409 /d "_DEBUG" /d "_AFXDLL"
# ADD RSC /l 0x409 /d "_DEBUG" /d "_AFXDLL"
BSC32=bscmake.exe
# ADD BASE BSC32 /nologo
# ADD BSC32 /nologo
LINK32=link.exe
# ADD BASE LINK32 /nologo /subsystem:windows /debug /machine:I386
# ADD LINK32 /nologo /subsystem:windows /debug /machine:I386

!ENDIF 

# Begin Target

# Name "ZhengModel - Win32 Release"
# Name "ZhengModel - Win32 Debug"
# Begin Group "Source Files"

# PROP Default_Filter "cpp;c;cxx;rc;def;r;odl;hpj;bat;for;f90"
# Begin Source File

SOURCE=.\Channel.cpp
# End Source File
# Begin Source File

SOURCE=.\ChildFrm.cpp
# End Source File
# Begin Source File

SOURCE=.\Compartment.cpp
# End Source File
# Begin Source File

SOURCE=.\DisplayPage.cpp
# End Source File
# Begin Source File

SOURCE=.\GlobalFncs.cpp
# End Source File
# Begin Source File

SOURCE=.\MainFrm.cpp
# End Source File
# Begin Source File

SOURCE=.\Mark_math.cpp
# End Source File
# Begin Source File

SOURCE=.\Neuron.cpp
# End Source File
# Begin Source File

SOURCE=.\NeuronPage.cpp
# End Source File
# Begin Source File

SOURCE=.\plot.cpp
# End Source File
# Begin Source File

SOURCE=.\PlotsDialog.cpp
# End Source File
# Begin Source File

SOURCE=.\ReadMe.txt
# End Source File
# Begin Source File

SOURCE=.\RunPage.cpp
# End Source File
# Begin Source File

SOURCE=.\Sensor.cpp
# End Source File
# Begin Source File

SOURCE=.\StdAfx.cpp
# ADD CPP /Yc"stdafx.h"
# End Source File
# Begin Source File

SOURCE=.\Synapse.cpp
# End Source File
# Begin Source File

SOURCE=.\TabCtrls.cpp
# End Source File
# Begin Source File

SOURCE=.\ZhengModel.cpp
# End Source File
# Begin Source File

SOURCE=.\ZhengModelDoc.cpp
# End Source File
# Begin Source File

SOURCE=.\ZhengModelView.cpp
# End Source File
# End Group
# Begin Group "Header Files"

# PROP Default_Filter "h;hpp;hxx;hm;inl;fi;fd"
# Begin Source File

SOURCE=.\Channel.h
# End Source File
# Begin Source File

SOURCE=.\ChildFrm.h
# End Source File
# Begin Source File

SOURCE=.\Compartment.h
# End Source File
# Begin Source File

SOURCE=.\DefaultParams.h
# End Source File
# Begin Source File

SOURCE=.\DisplayPage.h
# End Source File
# Begin Source File

SOURCE=.\GlobalDefs.h
# End Source File
# Begin Source File

SOURCE=.\GlobalFncs.h
# End Source File
# Begin Source File

SOURCE=.\MainFrm.h
# End Source File
# Begin Source File

SOURCE=.\Mark_math.h
# End Source File
# Begin Source File

SOURCE=.\Neuron.h
# End Source File
# Begin Source File

SOURCE=.\NeuronPage.h
# End Source File
# Begin Source File

SOURCE=.\plot.h
# End Source File
# Begin Source File

SOURCE=.\PlotsDialog.h
# End Source File
# Begin Source File

SOURCE=.\resource.h
# End Source File
# Begin Source File

SOURCE=.\RunPage.h
# End Source File
# Begin Source File

SOURCE=.\Sensor.h
# End Source File
# Begin Source File

SOURCE=.\StdAfx.h
# End Source File
# Begin Source File

SOURCE=.\Synapse.h
# End Source File
# Begin Source File

SOURCE=.\TabCtrls.h
# End Source File
# Begin Source File

SOURCE=.\ZhengModel.h
# End Source File
# Begin Source File

SOURCE=.\ZhengModelDoc.h
# End Source File
# Begin Source File

SOURCE=.\ZhengModelHeaders.h
# End Source File
# Begin Source File

SOURCE=.\ZhengModelView.h
# End Source File
# End Group
# Begin Group "Resource Files"

# PROP Default_Filter "ico;cur;bmp;dlg;rc2;rct;bin;cnt;rtf;gif;jpg;jpeg;jpe"
# Begin Source File

SOURCE=.\res\Toolbar.bmp
# End Source File
# Begin Source File

SOURCE=.\res\ZhengModel.ico
# End Source File
# Begin Source File

SOURCE=.\ZhengModel.rc
# End Source File
# Begin Source File

SOURCE=.\res\ZhengModel.rc2
# End Source File
# Begin Source File

SOURCE=.\res\ZhengModelDoc.ico
# End Source File
# End Group
# End Target
# End Project

Loading data, please wait...