Neocort. pyramidal cells subthreshold somatic voltage controls spike propagation (Munro Kopell 2012)

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Accession:136309
There is suggestive evidence that pyramidal cell axons in neocortex may be coupled by gap junctions into an ``axonal plexus" capable of generating Very Fast Oscillations (VFOs) with frequencies exceeding 80 Hz. It is not obvious, however, how a pyramidal cell in such a network could control its output when action potentials are free to propagate from the axons of other pyramidal cells into its own axon. We address this problem by means of simulations based on 3D reconstructions of pyramidal cells from rat somatosensory cortex. We show that somatic depolarization enables propagation via gap junctions into the initial segment and main axon, while somatic hyperpolarization disables it. We show further that somatic voltage cannot effectively control action potential propagation through gap junctions on minor collaterals; action potentials may therefore propagate freely from such collaterals regardless of somatic voltage. In previous work, VFOs are all but abolished during the hyperpolarization phase of slow-oscillations induced by anesthesia in vivo. This finding constrains the density of gap junctions on collaterals in our model and suggests that axonal sprouting due to cortical lesions may result in abnormally high gap junction density on collaterals, leading in turn to excessive VFO activity and hence to epilepsy via kindling.
Reference:
1 . Munro E, Kopell N (2012) Subthreshold somatic voltage in neocortical pyramidal cells can control whether spikes propagate from the axonal plexus to axon terminals: a model study. J Neurophysiol 107:2833-52 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell; Axon;
Brain Region(s)/Organism: Neocortex;
Cell Type(s): Neocortex L5/6 pyramidal GLU cell; Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell;
Channel(s): I Na,t; I K; I Sodium; I Potassium;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON; MATLAB;
Model Concept(s): Oscillations; Detailed Neuronal Models; Axonal Action Potentials; Epilepsy;
Implementer(s): Munro, Erin [ecmun at math.bu.edu];
Search NeuronDB for information about:  Neocortex L5/6 pyramidal GLU cell; Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell; I Na,t; I K; I Sodium; I Potassium;
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Munro_Kopell_corticalcontrol
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D3D_g0611P1.out
D3D_g0612P1.out
D3D_g0684P1.out
D3D_g0685P1.out
D3D_g0692P1.out
D3D_g0697P1.out
D3D_g0698P1.out
D3D_g0699P1.out
D3D_g0700P1.out
D3D_g0701P1.out
D3D_g0702P1.out
D3D_g0703P1.out
D3D_g0704P1.out
D3D_g0705P1.out
D3D_g0706P1.out
D3D_g0707P1.out
D3D_g0709P1.out
D3D_g0715_b.out
D3D_g0716_b.out
D3D_g0717_b.out
D3D_g0718_b.out
D3D_g0719_b.out
D3D_g0720_b.out
D3D_g0721_b.out
D3D_g0722_b.out
D3D_g0724P1.out
D3D_g0746_b.out
D3D_g0758_b.out
D3D_g0759_b2.out
D3D_g0760_b.out
D3D_g0761_b.out
D3D_g0762_b.out
D3D_g0763_b.out
D3D_GA01112c2-a.out
D3D_GA01703c2-a.out
D3D_GA01n06c1.out
D3D_GA01o29c1n2-2.out
D3D_GA02209c1n2-1.out
D3D_GA02212c2n3-1.out
D3D_GA02212c2n3-2.out
D3D_GA02219c1n2-1.out
D3D_GA02325c2n3-1.out
D3D_GA02326c1n2-1.out
D3D_GA02402c1n2-1.out
D3D_GA02403c2n3-1.out
D3D_GA02403c3n3-2.out
D3D_GA02531-C4.out
D3D_GA02605-3.out
D3D_gR001P1.out
D3D_gR002P1.out
D3D_gR003P1.out
D3D_I0319_3A.out
D3D_I0319_4A.out
D3D_I0319_5A.out
D3D_I0319_5B.out
D3D_I03192A.out
D3D_I03464.out
D3D_I03471.out
D3D_I03472.out
D3D_I03474.out
D3D_I03481.out
D3D_I03482.out
D3D_I03485.out
D3D_i03535.out
D3D_i03537.out
D3D_I03538.out
D3D_I03539.out
D3D_I03541.out
D3D_I03542.out
D3D_I03544.out
D3D_I03555.out
D3D_i03557.out
D3D_i03558.out
D3D_I03564.out
D3D_I03566.out
D3D_I03569.out
D3D_IF1_190301.out
D3D_IF1_210301.out
D3D_IF2_080501.out
D3D_IF3_040400.out
D3D_IF3_150300.out
D3D_IF3_261199.out
D3D_IF4_140201.out
D3D_JM011004-10-1.out
D3D_JM011004-10-2.out
D3D_JM011304-10-1.out
D3D_JM011504-10.out
D3D_JM011504-10-1.out
D3D_JM012004-30.out
D3D_JM012704-40-1.out
D3D_JM012804-40-2.out
D3D_JM020304-10-1.out
D3D_JM020404-30-1.out
D3D_JM072403-30.out
D3D_JM072803-10.out
D3D_JM072803-20.out
D3D_JM080703-30-1.out
D3D_JM082003-30-1.out
D3D_JM082003-30-2.out
D3D_JM082503-10-1.out
D3D_JM082503-10-2.out
D3D_JM082503-20.out
D3D_JM091503-20-1.out
D3D_JM091503-20-2.out
D3D_JM091503-20-3.out
D3D_JM091703-30-2.out
D3D_JM092303-10.out
D3D_JM092903-10-2.out
D3D_JMcell1or7-2.out
D3D_JMcell7or1-1.out
D3D_JMcell8or11-2.out
D3D_JMn030105-10-1.out
D3D_JMn030105-10-2.out
D3D_JMn030105-20-1.out
D3D_JMn030105-20-2.out
D3D_JMn032205-10-1.out
D3D_JMn091304-10-1.out
D3D_KP060107-2.out
D3D_KP060807p14-s1complete.out
D3D_KP062507complete.out
D3D_M050305SL1.out
D3D_M053005SL1.out
D3D_M060405SL1.out
D3D_MD070401-2.out
D3D_MD070424-4.out
D3D_MD070426-4.out
D3D_MD070456-4.out
D3D_MD070501-1.out
D3D_MD070501-2.out
D3D_MD070503-2-2.out
D3D_MD070517-2.out
D3D_MD070521-1.out
D3D_MD070521-2.out
D3D_MD070620-1.out
D3D_MD070629-1.out
D3D_MD232.out
D3D_MJ021506SL2.out
D3D_MJ030105-2-1.out
D3D_MJ033005-4.out
D3D_MJ042605-1.out
D3D_MJ050305-3.out
D3D_MJ061404-2-1.out
D3D_MJ061404-2-2.out
D3D_MJ061404-3.out
D3D_MJ070504-c1.out
D3D_MJ070504-c2.out
D3D_MJ070604-2.out
D3D_MJ072004-1.out
D3D_MJ080904-1.out
D3D_MJ090804-1-1.out
D3D_MJ090804-1-2.out
D3D_MJ090804-1-3.out
D3D_MJ090804-2-1.out
D3D_MJ090804-2-2.out
D3D_MJ090804-2-3.out
D3D_MJ090804-2-5.out
D3D_RA080304-1.out
D3D_RA080304-3.out
D3D_RosaG282A.out
D3D_RosaY131B.out
D3D_RosaY142A-incomplete.out
D3D_RosaY151B.out
D3D_TS060407s1c1complete.out
D3D_TS070804.out
D3D_Vn01062006-0-1-A.out
D3D_Vn01062006-0-1-B.out
D3D_Vn01132006-0-A.out
D3D_Vn01132006-0-C.out
D3D_Vn01162006-0-A.out
D3D_Vn01162006-0-B.out
D3D_Vn01162006-0-D.out
D3D_Vn01162006-1-C.out
D3D_Vn01232006-0-A.out
D3D_Vn01232006-0-B.out
D3D_Vn01232006-0-C.out
D3D_Vn02042006-0-C.out
D3D_Vn02042006-0-D.out
D3D_Vn02062006-1-B.out
D3D_Vn02062006-1-C.out
D3D_Vn02062006-1-D.out
D3D_Vn02162006-0-D.out
D3D_Vn02222006-0-D.out
D3D_Vn03082006-0-B.out
D3D_Vn03082006-0-C.out
D3D_Vn03082006-0-D.out
D3D_Vn03202006-1-A.out
D3D_Vn03202006-1-D.out
D3D_VN033105-1.out
D3D_VN033105-2.out
D3D_Vn03312005-1.out
D3D_Vn04012005-0-1.out
D3D_Vn04042006-0-A.out
D3D_Vn04042006-0-C.out
D3D_Vn04042006-0-D.out
D3D_VN041305-0-1.out
D3D_VN041305-0-2.out
D3D_VN041305-0-3.out
D3D_Vn04172006-0-D.out
D3D_VN04172006-1unfinished.out
D3D_Vn04182006-0-B.out
D3D_Vn04182006-0-D.out
D3D_Vn04192006-0-D.out
D3D_VN042105-0.out
D3D_Vn04212005-0-0.out
D3D_VN051305-a.out
D3D_VN051305-b.out
D3D_Vn05132005-1.out
D3D_Vn05192006-0-1.out
D3D_Vn05192006-1-B.out
D3D_Vn05302006-0-D.out
D3D_VN06012004-0.out
D3D_Vn06202006-0-B.out
D3D_Vn06202006-0-D.out
D3D_VN062404-1.out
D3D_Vn07132006-0-C.out
D3D_VN07142006-0-C.out
D3D_Vn07142006-1-C.out
D3D_Vn07142006-1-D.out
D3D_Vn07172006-0-B.out
D3D_VN071904.out
D3D_Vn07202006-0-D.out
D3D_Vn11302005-0-A.out
D3D_Vn12052005-0-A.out
D3D_Vn12052005-0-D.out
D3D_Vn12052005-1-A.out
D3D_Vn12052005-1-D.out
D3D_Vn12262005-1-C.out
D3D_Vn12262005-1-D.out
Markram_cells.txt
Markram_L5_cells.txt
rat_layer23.txt
rat_layer23_diams.txt
rat_layer4.txt
rat_layer4_diams.txt
rat_layer5.txt
rat_layer5_diams.txt
Staiger_cells.txt
Svoboda_cells.txt
Yuste_cells.txt
                            
0	0	160.759	1.24246	77.513	-38.514	-1.868	84.99	116.07	1.3	-1	2	76	1
1	160.759	3.3946	0.601789	84.99	116.07	1.3	83.6	119.07	1.3	0	2	63	2
2	164.153	5.52575	0.59	83.6	119.07	1.3	84.04	124.52	1.1	1	2	62	3
3	169.679	66.3162	0.59	84.04	124.52	1.1	95.44	187.75	2.75	2	2	5	4
4	235.995	114.334	0.609101	95.44	187.75	2.75	105.42	293.83	2.75	3	0	-1	-1
5	235.995	27.1964	0.463704	95.44	187.75	2.75	100.87	184.74	-11.6	3	2	51	6
6	263.192	136.028	0.307502	100.87	184.74	-11.6	154.48	155.47	-28.45	5	2	8	7
7	399.22	2.85284	0.37	154.48	155.47	-28.45	157.2	155.02	-28.45	6	0	-1	-1
8	399.22	0.99743	0.317167	154.48	155.47	-28.45	154.63	154.57	-28.55	6	2	12	9
9	400.217	12.8336	0.29	154.63	154.57	-28.55	153.45	166.59	-30.05	8	2	11	10
10	413.051	44.5539	0.255493	153.45	166.59	-30.05	114.92	171.44	-30.3	9	0	-1	-1
11	413.051	51.0957	0.245245	153.45	166.59	-30.05	149.85	214.97	-29.55	9	0	-1	-1
12	400.217	4.67865	0.259408	154.63	154.57	-28.55	157.51	151.57	-28	8	2	14	13
13	404.896	34.655	0.375354	157.51	151.57	-28	173.47	140.37	-30.7	12	0	-1	-1
14	404.896	135.105	0.292306	157.51	151.57	-28	136.72	38.29	-27.2	12	2	16	15
15	540.001	4.40346	0.29	136.72	38.29	-27.2	138.78	34.71	-27	14	0	-1	-1
16	540.001	7.23495	0.29	136.72	38.29	-27.2	132.75	34.78	-26.5	14	2	18	17
17	547.236	38.7245	0.221336	132.75	34.78	-26.5	140.62	61.28	-26.95	16	0	-1	-1
18	547.236	85.3512	0.29	132.75	34.78	-26.5	102.88	-39.38	-24.05	16	2	20	19
19	632.587	6.06545	0.163337	102.88	-39.38	-24.05	107.88	-40.06	-23.15	18	0	-1	-1
20	632.587	2.29476	0.23782	102.88	-39.38	-24.05	101.78	-41.25	-24	18	2	22	21
21	634.882	5.70669	0.22	101.78	-41.25	-24	100.01	-36.17	-24	20	0	-1	-1
22	634.882	99.8167	0.272595	101.78	-41.25	-24	91.9	-126.22	-16.45	20	2	24	23
23	734.698	7.76655	0.29	91.9	-126.22	-16.45	84.69	-124.43	-16.75	22	0	-1	-1
24	734.698	49.6669	0.29	91.9	-126.22	-16.45	98.29	-170.96	-13.65	22	2	46	25
25	784.365	109.935	0.29	98.29	-170.96	-13.65	93.97	-270.12	-9.6	24	2	27	26
26	894.301	12.2803	0.29	93.97	-270.12	-9.6	85.07	-265.94	-9.9	25	0	-1	-1
27	894.301	29.8883	0.29	93.97	-270.12	-9.6	83.31	-296.91	-10.6	25	2	29	28
28	924.189	1.62058	0.29	83.31	-296.91	-10.6	81.84	-297.36	-10.6	27	0	-1	-1
29	924.189	18.4223	0.29	83.31	-296.91	-10.6	79.42	-314.38	-10.95	27	2	31	30
30	942.611	5.08362	0.29	79.42	-314.38	-10.95	75.67	-312.81	-10.15	29	0	-1	-1
31	942.611	51.0845	0.29	79.42	-314.38	-10.95	69.72	-362.88	-10.5	29	2	35	32
32	993.696	13.0161	0.22366	69.72	-362.88	-10.5	59.06	-364.74	-11.65	31	2	34	33
33	1006.71	1.63885	0.22	59.06	-364.74	-11.65	59.8	-363.4	-11.65	32	0	-1	-1
34	1006.71	11.385	0.22	59.06	-364.74	-11.65	52.66	-357.8	-11.1	32	0	-1	-1
35	993.696	52.8851	0.341468	69.72	-362.88	-10.5	54.28	-410.86	-11.05	31	2	37	36
36	1046.58	19.67	0.22351	54.28	-410.86	-11.05	43.25	-407.87	-13.55	35	0	-1	-1
37	1046.58	146.192	0.334139	54.28	-410.86	-11.05	5.52	-534.7	-10.4	35	2	39	38
38	1192.77	4.32888	0.29	5.52	-534.7	-10.4	8.97	-537.16	-10.75	37	0	-1	-1
39	1192.77	79.225	0.360015	5.52	-534.7	-10.4	-53.83	-566.1	-7.9	37	2	41	40
40	1272	7.92123	0.292124	-53.83	-566.1	-7.9	-57.73	-567.67	-8.1	39	0	-1	-1
41	1272	11.6928	0.37	-53.83	-566.1	-7.9	-63.02	-571.92	-7.9	39	2	43	42
42	1283.69	19.2199	0.302323	-63.02	-571.92	-7.9	-69.49	-585.28	-8.6	41	0	-1	-1
43	1283.69	39.8043	0.335609	-63.02	-571.92	-7.9	-78.94	-604.04	-9.95	41	2	45	44
44	1323.5	41.7584	0.29	-78.94	-604.04	-9.95	-106.37	-616.58	-14.55	43	0	-1	-1
45	1323.5	13.6767	0.225591	-78.94	-604.04	-9.95	-78.42	-614.71	-10.9	43	0	-1	-1
46	784.365	8.99212	0.29	98.29	-170.96	-13.65	104.09	-168.47	-13.8	24	2	50	47
47	793.357	7.67647	0.224127	104.09	-168.47	-13.8	106.96	-161.91	-14.2	46	2	49	48
48	801.034	6.83564	0.22	106.96	-161.91	-14.2	106	-155.56	-14.25	47	0	-1	-1
49	801.034	37.6252	0.152734	106.96	-161.91	-14.2	126.2	-132.85	-14.25	47	0	-1	-1
50	793.357	42.6432	0.29	104.09	-168.47	-13.8	134.58	-175.91	-12.5	46	0	-1	-1
51	263.192	131.477	0.290858	100.87	184.74	-11.6	18.35	110.5	-13.7	5	2	55	52
52	394.668	13.8107	0.29	18.35	110.5	-13.7	9.33	100.6	-14.85	51	2	54	53
53	408.479	176.68	0.220166	9.33	100.6	-14.85	86.55	-20.6	-30.8	52	0	-1	-1
54	408.479	148.099	0.167515	9.33	100.6	-14.85	-29.92	-3.44	-14.7	52	0	-1	-1
55	394.668	201.808	0.29	18.35	110.5	-13.7	-106.47	12.62	-23.1	51	2	61	56
56	596.477	100.2	0.29	-106.47	12.62	-23.1	-164.62	-54.57	-24.4	55	2	58	57
57	696.677	9.19641	0.29	-164.62	-54.57	-24.4	-170.19	-60.73	-24.8	56	0	-1	-1
58	696.677	53.7619	0.29	-164.62	-54.57	-24.4	-205.05	-81.25	-25.85	56	2	60	59
59	750.439	1.82952	0.29	-205.05	-81.25	-25.85	-204.02	-82.35	-25.15	58	0	-1	-1
60	750.439	116.475	0.29	-205.05	-81.25	-25.85	-298.28	-126.33	-24.8	58	0	-1	-1
61	596.477	68.0296	0.29	-106.47	12.62	-23.1	-145.73	-12.21	-31.95	55	0	-1	-1
62	169.679	35.4251	0.239015	84.04	124.52	1.1	99.08	94.47	1.3	2	0	-1	-1
63	164.153	10.4011	0.381816	83.6	119.07	1.3	74.5	117.25	1.85	1	2	65	64
64	174.554	17.6674	0.199997	74.5	117.25	1.85	58.75	111.87	1.1	63	0	-1	-1
65	174.554	96.8795	0.292151	74.5	117.25	1.85	98.86	42.91	-3.55	63	2	75	66
66	271.434	14.0471	0.221727	98.86	42.91	-3.55	106.41	37.7	-6.45	65	2	68	67
67	285.481	165.858	0.22	106.41	37.7	-6.45	202.14	-50.06	-19.3	66	0	-1	-1
68	285.481	102.897	0.22	106.41	37.7	-6.45	178.25	-22.89	-5.5	66	2	70	69
69	388.378	2.03769	0.22	178.25	-22.89	-5.5	178.25	-20.91	-5.5	68	0	-1	-1
70	388.378	151.189	0.22	178.25	-22.89	-5.5	278.84	-118.58	-2.2	68	2	72	71
71	539.568	5.29926	0.158799	278.84	-118.58	-2.2	275.9	-121.59	-0.85	70	0	-1	-1
72	539.568	84.1392	0.22	278.84	-118.58	-2.2	336.2	-102.16	-3.95	70	2	74	73
73	623.707	10.0333	0.22	336.2	-102.16	-3.95	338.47	-110.37	-5.65	72	0	-1	-1
74	623.707	43.087	0.22	336.2	-102.16	-3.95	366.13	-95.93	-8.15	72	0	-1	-1
75	271.434	280.276	0.292562	98.86	42.91	-3.55	166.39	-89.53	-6.4	65	0	-1	-1
76	160.759	17.6316	0.308811	84.99	116.07	1.3	98.42	110.15	-0.7	0	2	114	77
77	178.39	71.5949	0.235185	98.42	110.15	-0.7	152.73	69.16	-0.55	76	2	109	78
78	249.985	2.55368	0.22	152.73	69.16	-0.55	154.86	67.83	-0.55	77	2	98	79
79	252.539	173.019	0.22	154.86	67.83	-0.55	275.96	-23.58	-7	78	2	81	80
80	425.558	1.82025	0.22	275.96	-23.58	-7	275.23	-25.2	-7.05	79	0	-1	-1
81	425.558	101.375	0.25519	275.96	-23.58	-7	336.78	-91.34	-11	79	2	89	82
82	526.933	115.27	0.22016	336.78	-91.34	-11	434.87	-106.76	-13.9	81	2	84	83
83	642.203	3.04229	0.22	434.87	-106.76	-13.9	436.78	-109.11	-13.9	82	0	-1	-1
84	642.203	184.02	0.22	434.87	-106.76	-13.9	574.11	-130.72	-23.9	82	2	86	85
85	826.224	10.2349	0.22	574.11	-130.72	-23.9	578.65	-138.56	-23.85	84	0	-1	-1
86	826.224	3.57164	0.22	574.11	-130.72	-23.9	572.86	-133.8	-23.85	84	2	88	87
87	829.795	3.07142	0.22	572.86	-133.8	-23.85	574.18	-135.63	-24.3	86	0	-1	-1
88	829.795	26.7077	0.177975	572.86	-133.8	-23.85	569.37	-158.62	-23.9	86	0	-1	-1
89	526.933	31.7307	0.338075	336.78	-91.34	-11	356.99	-109.62	-11.05	81	2	91	90
90	558.664	11.9796	0.294796	356.99	-109.62	-11.05	367.12	-106.76	-11.05	89	0	-1	-1
91	558.664	574.608	0.297362	356.99	-109.62	-11.05	794.05	-361.85	-18.95	89	2	93	92
92	1133.27	40.7156	0.247445	794.05	-361.85	-18.95	804.47	-345.21	-24.2	91	0	-1	-1
93	1133.27	46.6895	0.29	794.05	-361.85	-18.95	835.23	-362.84	-19.8	91	2	95	94
94	1179.96	122.873	0.29	835.23	-362.84	-19.8	919.78	-358.44	-22.85	93	0	-1	-1
95	1179.96	44.6487	0.29	835.23	-362.84	-19.8	856.14	-397.18	-20.75	93	2	97	96
96	1224.61	63.7767	0.22154	856.14	-397.18	-20.75	867.18	-446.74	-20.9	95	0	-1	-1
97	1224.61	39.6877	0.29	856.14	-397.18	-20.75	860.72	-432.15	-19.2	95	0	-1	-1
98	252.539	13.4689	0.323728	154.86	67.83	-0.55	153.76	58.42	-7.4	78	2	100	99
99	266.008	2.64624	0.326209	153.76	58.42	-7.4	152.88	60.81	-7.45	98	0	-1	-1
100	266.008	18.3085	0.37	153.76	58.42	-7.4	150.16	47.11	-5.8	98	2	108	101
101	284.316	235.019	0.343957	150.16	47.11	-5.8	2.84	-94.91	-8.7	100	2	103	102
102	519.335	2.38106	0.303775	2.84	-94.91	-8.7	2.84	-97.22	-8.7	101	0	-1	-1
103	519.335	131.259	0.325962	2.84	-94.91	-8.7	-23.26	-81.19	-26.8	101	2	105	104
104	650.594	3.61341	0.37	-23.26	-81.19	-26.8	-20.02	-80.51	-26.8	103	0	-1	-1
105	650.594	44.9735	0.316298	-23.26	-81.19	-26.8	-30.65	-45.49	-24.25	103	2	107	106
106	695.568	22.0275	0.278458	-30.65	-45.49	-24.25	-43.23	-58.78	-26.7	105	0	-1	-1
107	695.568	19.3965	0.357931	-30.65	-45.49	-24.25	-39.11	-38.48	-25.05	105	0	-1	-1
108	284.316	64.5983	0.22222	150.16	47.11	-5.8	165.01	-5.69	-4.8	100	0	-1	-1
109	249.985	39.3675	0.282887	152.73	69.16	-0.55	156.7	102.22	-7.7	77	2	113	110
110	289.353	80.3015	0.235968	156.7	102.22	-7.7	126.11	163.89	-10.05	109	2	112	111
111	369.654	6.57236	0.0884499	126.11	163.89	-10.05	125.3	169.87	-9.7	110	0	-1	-1
112	369.654	10.9162	0.203042	126.11	163.89	-10.05	117.21	166.43	-10	110	0	-1	-1
113	289.353	33.2527	0.179432	156.7	102.22	-7.7	132.64	112.2	-8.35	109	0	-1	-1
114	178.39	52.9366	0.215281	98.42	110.15	-0.7	138.62	108.03	0.5	76	0	-1	-1

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