Prefrontal–striatal Parkinsons comp. model of multicue category learning (Moustafa and Gluck 2011)


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Accession:138631
"... In this model, PFC dopamine is key for attentional learning, whereas basal ganglia dopamine, consistent with other models, is key for reinforcement and motor learning. The model assumes that competitive dynamics among PFC neurons is the neural mechanism underlying stimulus selection with limited attentional resources, whereas competitive dynamics among striatal neurons is the neural mechanism underlying action selection. According to our model, PD is associated with decreased phasic and tonic dopamine levels in both PFC and basal ganglia. ..."
Reference:
1 . Moustafa AA, Gluck MA (2011) A neurocomputational model of dopamine and prefrontal-striatal interactions during multicue category learning by Parkinson patients. J Cogn Neurosci 23(1):151-67
Model Information (Click on a link to find other models with that property)
Model Type:
Brain Region(s)/Organism: Neocortex; Striatum;
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Simulation Environment: MATLAB (web link to model);
Model Concept(s): Parkinson's;
Implementer(s):
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