A simple integrative electrophysiological model of bursting GnRH neurons (Csercsik et al. 2011)


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Accession:140246
In this paper a modular model of the GnRH neuron is presented. For the aim of simplicity, the currents corresponding to fast time scales and action potential generation are described by an impulsive system, while the slower currents and calcium dynamics are described by usual ordinary differential equations (ODEs). The model is able to reproduce the depolarizing afterpotentials, afterhyperpolarization, periodic bursting behavior and the corresponding calcium transients observed in the case of GnRH neurons.
Reference:
1 . Csercsik D, Farkas I, Hrabovszky E, Liposits Z (2012) A simple integrative electrophysiological model of bursting GnRH neurons. J Comput Neurosci 32(1):119-36 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): GnRH neuron;
Channel(s):
Gap Junctions:
Receptor(s): Glutamate; Gaba;
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB (web link to model);
Model Concept(s): Bursting; Active Dendrites; Action Potentials; Calcium dynamics;
Implementer(s):
Search NeuronDB for information about:  Glutamate; Gaba;
(located via links below)
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