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Multiscale interactions between chemical and electric signaling in LTP (Bhalla 2011)
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"Synaptic plasticity leads to long-term changes in excitability, whereas cellular homeostasis maintains excitability. Both these processes involve interactions between molecular events, electrical events, and network activity. Here I explore these intersections with a multilevel model that embeds molecular events following synaptic calcium influx into a multicompartmental electrical model of a CA1 hippocampal neuron. ..."
Bhalla US (2011) Multiscale interactions between chemical and electric signaling in LTP induction, LTP reversal and dendritic excitability.
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Neuron or other electrically excitable cell;
Hippocampus CA1 pyramidal cell;
Long-term Synaptic Plasticity;
Bhalla, Upinder S [bhalla at ncbs.res.in];
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Hippocampus CA1 pyramidal cell
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