Circadian clock model in mammals (PK/PD model) (Kim & Forger 2013)

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Accession:148320
A systems pharmacology model of the mammalian circadian clock including PF-670462 (CK1d/e inhibitor).
Reference:
1 . Kim JK, Forger DB, Marconi M, Wood D, Doran A, Wager T, Chang C, Walton KM (2013) Modeling and validating chronic pharmacological manipulation of circadian rhythms CPT: Pharmacometrics & Systems Pharmacology 2(7):1-11
Model Information (Click on a link to find other models with that property)
Model Type: Molecular Network;
Brain Region(s)/Organism:
Cell Type(s): Suprachiasmatic nucleus (SCN) neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: Mathematica;
Model Concept(s): Therapeutics; Phase Response Curves; Circadian Rhythms;
Implementer(s): Kim, Jae Kyoung [kimjack0 at kaist.ac.kr];
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README.txt
PF-670462_Model.nb
                            
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