" ... A computational model,
which simulated molecular processes underlying long-term
synaptic facilitation (LTF) induction, predicted a rescue protocol of five pulses of 5-HT at non-uniform interstimulus
intervals that overcame the consequences of reduced CREB-binding protein (CBP) and restored LTF. ..."
Liu RY, Zhang Y, Baxter DA, Smolen P, Cleary LJ, Byrne JH (2013) Deficit in Long-Term Synaptic Plasticity Is Rescued by a Computationally
Predicted Stimulus Protocol
J. Neurosci. 33:6944-6949