A spatial model of the intermediate superior colliculus (Moren et. al. 2013)

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Accession:168866
A spatial model of the intermediate superior colliculus. It reproduces the collicular saccade-generating output profile from NMDA receptor-driven burst neurons, shaped by integrative inhibitory feedback from spreading buildup neuron activity. The model is consistent with the view that collicular activity directly shapes the temporal profile of saccadic eye movements. We use the Adaptive exponential integrate and fire neuron model, augmented with an NMDA-like membrane potential-dependent receptor. In addition, we use a synthetic spike integrator model as a stand-in for a spike-integrator circuit in the reticular formation. NOTE: We use a couple of custom neuron models, so the supplied model file includes an entire version of NEST. I also include a patch that applies to a clean version of the simulator (see the doc/README).
Reference:
1 . Moren J, Shibata T, Doya K (2013) The mechanism of saccade motor pattern generation investigated by a large-scale spiking neuron model of the superior colliculus. PLoS One 8:e57134 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Connectionist Network;
Brain Region(s)/Organism: Superior colliculus;
Cell Type(s): Abstract integrate-and-fire adaptive exponential (AdEx) neuron;
Channel(s):
Gap Junctions:
Receptor(s): NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEST; Python;
Model Concept(s): Activity Patterns; Bursting; Spatio-temporal Activity Patterns; Action Selection/Decision Making;
Implementer(s):
Search NeuronDB for information about:  NMDA;
/
NEST-SCModel
doc
nest-2.2.2
patches
supcoll
README
init.sh
                            
This is an upper-level README for the model associated with the paper:

Moren J, Shibata T, Doya K (2013) The mechanism of saccade motor
pattern generation investigated by a large-scale spiking neuron model
of the superior colliculus. PLoS One 8:e57134

A spatial model of the intermediate superior colliculus. It reproduces
the collicular saccade-generating output profile from NMDA
receptor-driven burst neurons, shaped by integrative inhibitory
feedback from spreading buildup neuron activity. The model is
consistent with the view that collicular activity directly shapes the
temporal profile of saccadic eye movements.

We use the Adaptive exponential integrate and fire neuron model,
augmented with an NMDA-like membrane potential-dependent receptor. In
addition, we use a synthetic spike integrator model as a stand-in for
a spike-integrator circuit in the reticular formation.

NOTE: We use a couple of custom neuron models, so the supplied model
file includes an entire version of NEST. I also include a patch that
applies to a clean version of the simulator (see the doc/readme for
installation and usage).

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