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Mean-field systems and small scale neural networks (Ferguson et al. 2015)
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We explore adaptation induced bursting as a mechanism for theta oscillations in hippocampal area CA1. To do this, we have developed a mean-field system for a network of fitted Izhikevich neurons with sparse coupling and heterogeneity. The code contained here runs the mean-field system pointwise or on a two-parameter mesh, in addition to networks of neurons that are smaller then those considered in the paper. The file README.pdf contains instructions on use. Note that the following file (peakfinder): http://www.mathworks.com/matlabcentral/fileexchange/25500-peakfinder-x0--sel--thresh--extrema--includeendpoints--interpolate- is required to compute burst frequencies in the mean-field system and must be downloaded and placed in the same root folder as MFSIMULATOR.mat
Ferguson KA, Njap F, Nicola W, Skinner FK, Campbell SA (2015) Examining the limits of cellular adaptation bursting mechanisms in biologically-based excitatory networks of the hippocampus.
J Comput Neurosci
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Abstract Izhikevich neuron;
Nicola, Wilten [wnicola at uwaterloo.ca];
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