Dendritic tip geometry effects electrical properties (Tsutsui, Oka 2001)

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Accession:18738
In their teleost thalamic neuron models the authors demonstrate a dramatic increase in the passive propagation of synaptic inputs through the dendritic stalk to the soma in cells with larger tips.
Reference:
1 . Tsutsui H, Oka Y (2001) Effects of characteristic dendritic tip geometry on the electrical properties of teleost thalamic neurons. J Neurophysiol 85:2289-92 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Teleost thalamic neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Influence of Dendritic Geometry;
Implementer(s): Tsutsui, H ;
/
dendgeom
readme.txt
fig2A.ses
mosinit.hoc
                            
Model program for the paper:

Tsutsui H, Oka Y.
Effects of characteristic dendritic tip geometry on the electrical
properties of teleost thalamic neurons.
J Neurophysiol 2001 May;85(5):2289-92

Running the mosinit.hoc program with Neuron recreates Fig 2A.
The fig2A.ses file can also be run by itself with Neuron.

The abstract from the paper:

 Of the factors that characterize the properties and functions of 
 neurons, dendritic geometry is one of the most critical. We used 
 simulations employing the multi-compartment model to study the 
 effects of dendritic tip geometry on the electrical properties of 
 the "large cell" in a teleost thalamic nucleus from the corpus 
 glomerulosum. We demonstrated a dramatic geometrical "boosting" 
 effect; passive propagation of the synaptic inputs from the 
 dendritic tip to the soma through the dendritic stalk is less 
 attenuated in cells with larger tips. 

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