Fully continuous Pinsky-Rinzel model for bifurcation analysis (Atherton et al. 2016)

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Accession:189088
The original, 2-compartment, CA3 cell, Pinsky-Rinzel model (Pinsky, Rinzel 1994) has several discontinuous functions that prevent the use of standard bifurcation analysis tools to study the model. Here we present a modified, fully continuous system that captures the behaviour of the original model, while permitting the use of available numerical continuation software to perform full-system bifurcation and fast-slow analysis in XPPAUT.
Reference:
1 . Atherton LA, Prince LY, Tsaneva-Atanasova K (2016) Bifurcation analysis of a two-compatment hippocampal pyramidal cell model Journal of Computational Neuroscience (provisionally accepted)
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA1 pyramidal cell; Hippocampus CA3 pyramidal cell; Pinsky-Rinzel CA1/3 pyramidal cell ;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: XPP; XPP (web link to model); Python;
Model Concept(s): Bursting; Bifurcation;
Implementer(s): Atherton, Laura ; Prince, Luke ;
Search NeuronDB for information about:  Hippocampus CA1 pyramidal cell; Hippocampus CA3 pyramidal cell;

Atherton LA, Prince LY, Tsaneva-Atanasova K (2016) Bifurcation analysis of a two-compatment hippocampal pyramidal cell model Journal of Computational Neuroscience (provisionally accepted)

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