"... To analyze the temperature effect, our study modified
the classical HH axonal model by incorporating a membrane
capacitance-temperature relationship. The modified model
successfully simulated the generation and propagation of action
potentials induced by a rapid increase in local temperature
when the Curie temperature of membrane capacitance is below
40 °C, while the classical model failed to simulate the
axonal excitation by temperature stimulation. The new model
predicts that a rapid increase in local temperature produces a
rapid increase in membrane capacitance, which causes an inward
membrane current across the membrane capacitor strong
enough to depolarize the membrane and generate an action
potential. ..."
Reference:
1 .
Fribance S, Wang J, Roppolo JR, de Groat WC, Tai C (2016) Axonal model for temperature stimulation. J Comput Neurosci 41:185-92 [PubMed]
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