VTA dopamine neuron (Tarfa, Evans, and Khaliq 2017)

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Accession:226254
In our model of a midbrain VTA dopamine neuron, we show that the decay kinetics of the A-type potassium current can control the timing of rebound action potentials.
Reference:
1 . Tarfa RA, Evans RC, Khaliq ZM (2017) Enhanced Sensitivity to Hyperpolarizing Inhibition in Mesoaccumbal Relative to Nigrostriatal Dopamine Neuron Subpopulations. J Neurosci 37:3311-3330 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Basal ganglia;
Cell Type(s): Ventral tegmental area dopamine neuron;
Channel(s): I A; I A, slow; I K,Ca; I Calcium; I Na, leak; I Na,t; I T low threshold; I L high threshold; I h; I K; I N; I R;
Gap Junctions:
Receptor(s): GabaA; AMPA; NMDA;
Gene(s):
Transmitter(s): Gaba;
Simulation Environment: GENESIS;
Model Concept(s): Ion Channel Kinetics; Action Potentials; Activity Patterns;
Implementer(s): Evans, Rebekah [Rebekah.Evans at nih.gov];
Search NeuronDB for information about:  GabaA; AMPA; NMDA; I Na,t; I L high threshold; I N; I T low threshold; I A; I K; I h; I K,Ca; I Calcium; I A, slow; I R; I Na, leak; Gaba;
/************************ VTA v2.14 PreSyn.g *********************
*****Functions to create presynaptic input to synaptic channels*****
Function is called by stimulation files in DAstim such as GABAstim.g

Rebekah Evans rebekah.evans@nih.gov

**************************************************************************/

function make_presynaptic_terminals (number)
	int number
	int i=0
	for (i = 0; i < {number}; i = i + 1)
		create compartment presyn{i}
		create spikegen presyn{i}/spike
		setfield presyn{i}/spike thresh 1
		addmsg presyn{i} presyn{i}/spike INPUT Vm
	end
end



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