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Model for concentration invariant odor coding based on primacy hypothesis (Wilson et al 2017)
 
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Model Information
Model File
Citations
Accession:
231814
"... Here we propose that, in olfaction, a small and relatively stable set comprised of the earliest activated receptors forms a code for concentration-invariant odor identity. One prediction of this “primacy coding” scheme is that decisions based on odor identity can be made solely using early odor-evoked neural activity. Using an optogenetic masking paradigm, we define the sensory integration time necessary for odor identification and demonstrate that animals can use information occurring <100ms after inhalation onset to identify odors. ... We propose a computational model demonstrating how such a code can be read by neural circuits of the olfactory system."
Reference:
1 .
Wilson CD, Serrano GO, Koulakov AA, Rinberg D (2017) A primacy code for odor identity.
Nat Commun
8
:1477
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Mouse;
Cell Type(s):
Olfactory bulb main mitral GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gaseous Receptors;
Gene(s):
Transmitter(s):
Gaba;
Simulation Environment:
MATLAB;
Model Concept(s):
Activity Patterns;
Olfaction;
Implementer(s):
Koulakov, Alexei [akula at cshl.edu];
Search NeuronDB
for information about:
Olfactory bulb main mitral GLU cell
;
Gaseous Receptors
;
Gaba
;
/
primacy
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