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Model of the cerebellar granular network (Sudhakar et al 2017)
 
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Model Information
Model File
Citations
Accession:
232023
"The granular layer, which mainly consists of granule and Golgi cells, is the first stage of the cerebellar cortex and processes spatiotemporal information transmitted by mossy fiber inputs with a wide variety of firing patterns. To study its dynamics at multiple time scales in response to inputs approximating real spatiotemporal patterns, we constructed a large-scale 3D network model of the granular layer. ..."
Reference:
1 .
Sudhakar SK, Hong S, Raikov I, Publio R, Lang C, Close T, Guo D, Negrello M, De Schutter E (2017) Spatiotemporal network coding of physiological mossy fiber inputs by the cerebellar granular layer.
PLoS Comput Biol
13
:e1005754
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Cerebellum;
Cell Type(s):
Cerebellum golgi cell;
Channel(s):
I A;
I Calcium;
I K;
I K,Ca;
I Na,t;
I h;
I Na,p;
I T low threshold;
Gap Junctions:
Gap junctions;
Receptor(s):
AMPA;
NMDA;
Gaba;
Gene(s):
Transmitter(s):
Glutamate;
Gaba;
Simulation Environment:
NEURON;
Model Concept(s):
Spatio-temporal Activity Patterns;
Oscillations;
Synchronization;
Winner-take-all;
Implementer(s):
Hong, Sungho [shhong at oist.jp];
Guo, Daqing [dqguo at uestc.edu.cn];
Raikov, Ivan [ivan.g.raikov at gmail.com];
Publio, Rodrigo [publio at oist.jp];
De Schutter, Erik [erik at oist.jp];
Search NeuronDB
for information about:
AMPA
;
NMDA
;
Gaba
;
I Na,p
;
I Na,t
;
I T low threshold
;
I A
;
I K
;
I h
;
I K,Ca
;
I Calcium
;
Gaba
;
Glutamate
;
/
cerebellar_granular_network
mechanisms
Event_stream
gap
Golgi_CL
Granule_CL
Presynaptic_spike_generator
Synapses
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