//genesis
//kleak-paired.g
function make_kleak(path, gbar, vpath)
str path
float gbar
float area
if ({vpath} == "/rhab/vm")
area={rhabSA}/{rhabcyls}
else
area = {getfield {path} SAout }
end
//echo {vpath} {area}
create ligand2_chan {path}/kleak /* units are msec, nA, uS, mV */
setfield {path}/kleak \
k1f.min 300e-3 \
k1f.max 0.0 \
k1f.slope -20 \
k1f.v0 -20.0 \
k1f.in_exp_power 1 \
k1f.out_exp_power -1 \
k1f.in_exp_offset 0 \
k1f.out_exp_offset 1 \
k1b.min 0.8e-3 \
k1b.max 0.0 \
k1b.slope 10.0 \
k1b.v0 -23.0 \
k1b.in_exp_power 1 \
k1b.out_exp_power -1 \
k1b.in_exp_offset 0 \
k1b.out_exp_offset 1 \
k2f.min 3000e-3 \
k2f.max 0.0 \
k2f.slope -20 \
k2f.v0 -20.0 \
k2f.in_exp_power 1 \
k2f.out_exp_power -1 \
k2f.in_exp_offset 0 \
k2f.out_exp_offset 1 \
k2b.min 0.08e-3 \
k2b.max 0.0 \
k2b.slope 10.0 \
k2b.v0 -23.0 \
k2b.in_exp_power 1 \
k2b.out_exp_power -1 \
k2b.in_exp_offset 0 \
k2b.out_exp_offset 1 \
gamma.slope -20 \
gamma.min 0 \
gamma.max 0 \
gamma.in_exp_power 1 \
gamma.out_exp_power -1 \
gamma.in_exp_offset 0 \
gamma.out_exp_offset 1 \
delta.slope -20 \
delta.min 0 \
delta.max 0 \
delta.in_exp_power 1 \
delta.out_exp_power -1 \
delta.in_exp_offset 0 \
delta.out_exp_offset 1 \
Vr -85.0 \
rxn_ord1 1 \
rxn_ord2 1 \
cond_state 0 \
Gbar {gbar*area}
end
/********************************************************************/
function kleak_comp (vpath, capath, startcyl, endcyl, gbar)
str vpath, capath
int startcyl, endcyl
float gbar
int i
for (i=startcyl; i<=endcyl; i=i+1)
make_kleak {capath}[{i}] {gbar} {vpath}
addmsg {capath}[{i}] {capath}[{i}]/kleak LIGAND Conc
addmsg {vpath} {capath}[{i}]/kleak VOLTAGE Vm
addmsg {capath}[{i}]/kleak {vpath} CHANNEL G Vr
end
end
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