Squid axon (Hodgkin, Huxley 1952) (NEURON)

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Accession:5426
The classic HH model of squid axon membrane implemented in NEURON. Hodgkin, A.L., Huxley, A.F. (1952)
Reference:
1 . HODGKIN AL, HUXLEY AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117:500-44 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Axon;
Brain Region(s)/Organism:
Cell Type(s): Squid axon; Hodgkin-Huxley neuron;
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potentials; Invertebrate;
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB for information about:  I Na,t; I K;
load_file("nrngui.hoc")
objectvar save_window_, rvp_
objectvar scene_vector_[3]
objectvar ocbox_, ocbox_list_, scene_, scene_list_
{ocbox_list_ = new List()  scene_list_ = new List()}
{pwman_place(0,0,0)}

//Begin PointProcessManager
{
load_file("pointman.hoc")
}
{
soma ocbox_ = new PointProcessManager(0)
}
{object_push(ocbox_)}
{
mt.select("SEClamp") i = mt.selected()
ms[i] = new MechanismStandard("SEClamp")
ms[i].set("rs", 0.1, 0)
ms[i].set("dur1", 0, 0)
ms[i].set("amp1", -65, 0)
ms[i].set("dur2", 12, 0)
ms[i].set("amp2", -59, 0)
ms[i].set("dur3", 0, 0)
ms[i].set("amp3", 0, 0)
mt.select("SEClamp") i = mt.selected() maction(i)
hoc_ac_ = 0.5
sec.sec move() d1.flip_to(0)
}
{object_pop() doNotify()}
{
ocbox_ = ocbox_.v1
ocbox_.map("PointProcessManager", 169, 113, 237.12, 401.28)
}
objref ocbox_
//End PointProcessManager


//Begin Insert/Remove Mechanisms
{
load_file("inserter.hoc", "Inserter")
}
{
soma ocbox_ = new Inserter(0)
}
{object_push(ocbox_)}
{
mt.select("hh") i = mt.selected()
ms[i] = new MechanismStandard("hh")
ms[i].set("gnabar_hh", 0.0707, 0)
ms[i].set("gkbar_hh", 0.02431, 0)
ms[i].set("gl_hh", 0.0003, 0)
ms[i].set("el_hh", -54.3, 0)
mstate[i]= 1
maction(i)
}
{object_pop() doNotify()}
{
ocbox_ = ocbox_.v1
ocbox_.map("Insert/Remove Mechanisms", 431, 27, 91.2, 92.16)
}
objref ocbox_
//End Insert/Remove Mechanisms


//Begin MulRunFitter[0]
{
load_file("mulfit.hoc", "MulRunFitter")
}
{
ocbox_ = new MulRunFitter(1)
}
{object_push(ocbox_)}
{
version(2)
ranfac = 2
fspec = new File("hhkfit.ses.ft1")
fdat = new File("hhkfit.ses.fd1")
read_data()
build()
}
{object_pop()}
{
ocbox_.map("MulRunFitter[0]", 541, 29, 367.68, 299.52)
}
objref ocbox_
//End MulRunFitter[0]

{
xpanel("RunControl", 0)
v_init = -65
xvalue("Init","v_init", 1,"stdinit()", 1, 1 )
xbutton("Init & Run","run()")
xbutton("Stop","stoprun=1")
runStopAt = 5
xvalue("Continue til","runStopAt", 1,"{continuerun(runStopAt) stoprun=1}", 1, 1 )
runStopIn = 1
xvalue("Continue for","runStopIn", 1,"{continuerun(t + runStopIn) stoprun=1}", 1, 1 )
xbutton("Single Step","steprun()")
t = 12
xvalue("t","t", 2 )
tstop = 12
xvalue("Tstop","tstop", 1,"tstop_changed()", 0, 1 )
dt = 0.025
xvalue("dt","dt", 1,"setdt()", 0, 1 )
steps_per_ms = 40
xvalue("Points plotted/ms","steps_per_ms", 1,"setdt()", 0, 1 )
xcheckbox("Quiet",&stdrun_quiet,"")
realtime = 0
xvalue("Real Time","realtime", 0,"", 0, 1 )
xpanel(173,560)
}
objectvar scene_vector_[1]
{doNotify()}

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