Squid axon (Hodgkin, Huxley 1952) (NEURON)

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Accession:5426
The classic HH model of squid axon membrane implemented in NEURON. Hodgkin, A.L., Huxley, A.F. (1952)
Reference:
1 . HODGKIN AL, HUXLEY AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117:500-44 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Axon;
Brain Region(s)/Organism:
Cell Type(s): Squid axon; Hodgkin-Huxley neuron;
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potentials; Invertebrate;
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB for information about:  I Na,t; I K;
ParmFitness: Figure 3 K conductance
	FitnessGenerator: 6 mV step from rest
		RunConstant:	SEClamp[0].amp2 -59 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 10 mV step from rest
		RunConstant:	SEClamp[0].amp2 -55 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 19 mV step from rest
		RunConstant:	SEClamp[0].amp2 -46 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 26 mV step from rest
		RunConstant:	SEClamp[0].amp2 -39 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 32 mV step from rest
		RunConstant:	SEClamp[0].amp2 -33 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 38 mV step from rest
		RunConstant:	SEClamp[0].amp2 -27 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 51 mV step from rest
		RunConstant:	SEClamp[0].amp2 -14 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 63 mV step from rest
		RunConstant:	SEClamp[0].amp2 -2 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 76 mV step from rest
		RunConstant:	SEClamp[0].amp2 11 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 88 mV step from rest
		RunConstant:	SEClamp[0].amp2 23 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 100 mV step from rest
		RunConstant:	SEClamp[0].amp2 35 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	FitnessGenerator: 109 mV step from rest
		RunConstant:	SEClamp[0].amp2 44 -59
				SEClamp[0].dur1 0 0
		RegionFitness:	soma.gk_hh( 0.5 )

	Parameters:
		"soma.gkbar_hh( 0.5 )", 0.02431, -1e+06, 1e+06, 1, 0
End ParmFitness

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