A dynamic model of the canine ventricular myocyte (Hund, Rudy 2004)


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Accession:55756
The Hund-Rudy dynamic (HRd) model is based on data from the canine epicardial ventricular myocyte. Rate-dependent phenomena associated with ion channel kinetics, action potential properties and Ca2+ handling are simulated by the model. See paper for more and details.
Reference:
1 . Hund TJ, Rudy Y (2004) Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model. Circulation 110:3168-74 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Electrogenic pump;
Brain Region(s)/Organism:
Cell Type(s): Heart cell; Cardiac ventricular cell;
Channel(s): I Chloride; I Na,t; I K; I Calcium; Na/K pump;
Gap Junctions:
Receptor(s):
Gene(s):
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Simulation Environment: MATLAB (web link to model); C or C++ program (web link to model);
Model Concept(s): Ion Channel Kinetics; Action Potentials; Heart disease; Sodium pump;
Implementer(s): Decker, Keith [keithforestdecker at gmail.com]; Livshitz, Leonid [livshitz at wustl.edu]; Hund, Tom [thund at pathology.wustl.edu];
Search NeuronDB for information about:  I Chloride; I Na,t; I K; I Calcium; Na/K pump;
(located via links below)
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