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A dynamic model of the canine ventricular myocyte (Hund, Rudy 2004)
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Model Information
Model File
Citations
Accession:
55756
The Hund-Rudy dynamic (HRd) model is based on data from the canine epicardial ventricular myocyte. Rate-dependent phenomena associated with ion channel kinetics, action potential properties and Ca2+ handling are simulated by the model. See paper for more and details.
Reference:
1 .
Hund TJ, Rudy Y (2004) Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model.
Circulation
110
:3168-74
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Electrogenic pump;
Brain Region(s)/Organism:
Cell Type(s):
Heart cell;
Cardiac ventricular cell;
Channel(s):
I Chloride;
I Na,t;
I K;
I Calcium;
Na/K pump;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
MATLAB (web link to model);
C or C++ program (web link to model);
Model Concept(s):
Ion Channel Kinetics;
Action Potentials;
Heart disease;
Sodium pump;
Implementer(s):
Decker, Keith [keithforestdecker at gmail.com];
Livshitz, Leonid [livshitz at wustl.edu];
Hund, Tom [thund at pathology.wustl.edu];
Search NeuronDB
for information about:
I Chloride
;
I Na,t
;
I K
;
I Calcium
;
Na/K pump
;
(located via links below)
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