Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Basal ganglia-thalamocortical loop model of action selection (Humphries and Gurney 2002)
Download zip file
Help downloading and running models
We embed our basal ganglia model into a wider circuit containing the motor thalamocortical loop and thalamic reticular nucleus (TRN). Simulation of this extended model showed that the additions gave five main results which are desirable in a selection/switching mechanism. First, low salience actions (i.e. those with low urgency) could be selected. Second, the range of salience values over which actions could be switched between was increased. Third, the contrast between the selected and non-selected actions was enhanced via improved differentiation of outputs from the BG. Fourth, transient increases in the salience of a non-selected action were prevented from interrupting the ongoing action, unless the transient was of sufficient magnitude. Finally, the selection of the ongoing action persisted when a new closely matched salience action became active. The first result was facilitated by the thalamocortical loop; the rest were dependent on the presence of the TRN. Thus, we conclude that the results are consistent with these structures having clearly defined functions in action selection.
Humphries MD (2003) High level modeling of dopamine mechanisms in striatal neurons
Technical Report ABRG 3
Humphries MD, Gurney KN (2002) The role of intra-thalamic and thalamocortical circuits in action selection.
(Click on a link to find other models with that property)
Action Selection/Decision Making;
Humphries, Mark D [m.d.humphries at shef.ac.uk];
for information about:
File not selected
<- Select file from this column.
Loading data, please wait...