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A model of local field potentials generated by medial superior olive neurons (Goldwyn et al 2014)
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A computational model of local field potentials generated by medial superior olive neurons. These field potentials are known as the "auditory neurophonic". MSO neuron is modeled as a soma and two dendrites (following Mathews et al, Nature Neurosci, 2010). Intracellular and a 1D extracellular domain are dynamically coupled and solved to simulate spatial-temporal patterns of membrane voltage and extracellular voltage in response to trains of synaptic inputs (monolateral or bilateral, excitation and/or inhibition). The model produces spatio-temporal patterns similar to neurophonic responses recorded in vivo, as discussed in the accompanying manuscript.
Goldwyn JH, Mc Laughlin M, Verschooten E, Joris PX, Rinzel J (2014) A model of the medial superior olive explains spatiotemporal features of local field potentials.
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Neuron or other electrically excitable cell;
Medial Superior Olive (MSO) cell;
Goldwyn, Joshua [jhgoldwyn at gmail.com];
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