ModelDB: CA3 pyramidal neurons: Kv1.2 mediates modulation of cortical inputs (Hyun et al., 2015)

CA3 pyramidal neurons: Kv1.2 mediates modulation of cortical inputs (Hyun et al., 2015)

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Accession:184139

This model simulates the contribution of dendritic Na+ and D-type K+ channels to EPSPs at three different locations of apical dendrites, which mimicking innervation sites of mossy fibers (MF), recurrent fibers (AC), and perforant pathway (PP).
Reference:
1 . Hyun JH, Eom K, Lee KH, Bae JY, Bae YC, Kim MH, Kim S, Ho WK, Lee SH (2015) Kv1.2 mediates heterosynaptic modulation of direct cortical synaptic inputs in CA3 pyramidal cells. J Physiol 593:3617-43 [PubMed]

Model Information (Click on a link to find other models with that property)

Model Type:	Dendrite;
Brain Region(s)/Organism:
Cell Type(s):	Hippocampus CA3 pyramidal GLU cell;
Channel(s):	I A; I Sodium; I_KD;
Gap Junctions:
Receptor(s):
Gene(s):	Kv1.2 KCNA2;
Transmitter(s):
Simulation Environment:	NEURON;
Model Concept(s):	Dendritic Action Potentials;
Implementer(s):