Membrane Properties: Receptors

This inventory gives a complete overview of the main types of membrane receptors that have been identified for neurotransmitters and neuromodulators. Supporting data to fill the tables is still being added. The list of receptors for NeuronDB is a subset of this inventory. The inventory is based on Alexander & Peters (2000)

List of receptors (alphabetical)


Select a receptor:
5-Hydroxytryptamine receptors ,    Acetylcholine receptors , Muscarinic   Acetylcholine receptors , Nicotinic   Adenosine receptors ,    Adrenoceptors , alpha1   Adrenoceptors , alpha2   Adrenoceptors , beta   Angiotensin receptors ,    Atrial natriuretic peptide receptors ,    Bombesin receptors ,    Bradykinin receptors ,    Calcitonin, amylin, CGRP and adrenomedullin receptors ,    Cannabinoid receptors ,    Chemokine receptors , CC   Chemokine receptors , CX3C   Chemotactic peptide receptors ,    Cholecystokinin and gastrin receptors ,    Corticotropin-releasing factor rceptors ,    Dopamine receptors ,    Endothelin receptors ,    GABA receptors , A   GABA receptors , B   Galanin receptors ,    Glutamate receptors , Ionotropic   Glutamate receptors , Metabotropic   Glycine receptors ,    Glycoprotein hormone receptors ,    Histamine receptors ,    Ins(1,4,5)P3(IP3) receptors ,    Leukotriene receptors ,    Lysophospholipid receptors ,    Melanocortin receptors ,    Melatonin receptors ,    Neuropeptide Y receptors ,    Neurotensin receptors ,    Neurotrophin receptors ,    Opioid and opioid-like receptors ,    P2X receptors (transmitter-gated channels) ,    P2Y receptors (G-protein-coupled) ,    Peroxisome proliferator activated receptors ,    Prostanoid receptors ,    Protease-activated receptors ,    Ryanodine receptors ,    Somatostatin receptors ,    Steroid hormone receptors ,    Tachykinin receptors ,    Thyrotropin-releasing hormone receptors ,    Vasoactive intentinal peptide and pituitary adenylate cyclase activating peptide receptors ,    Vasopressin and oxytocin receptors ,    
Show receptors individually

ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
5-Hydroxytryptamine receptors,5-HT1A HTR1A /5q11.2-q13   7TM Gi/o   
5-Hydroxytryptamine receptors,5-HT1B HTR1B / 6q13   7TM Gi/o   
5-Hydroxytryptamine receptors,5-HT1D HTR1D / 1p34.3-36.3   7TM Gi/o   
5-Hydroxytryptamine receptors,5-ht1E HTR1E / 6q14-15   7TM Gi/o   
5-Hydroxytryptamine receptors,5-ht1F HTR1F / 3p11   7TM Gi/o   
5-Hydroxytryptamine receptors,5-HT2A HTR2A / 13q14 -q21   7TM Gq/11   
5-Hydroxytryptamine receptors,5-HT2B HTR2B / 2q36.3 -2q37.1   7TM Gq/11   
5-Hydroxytryptamine receptors,5-HT2C HTR2C / Xq24   7TM Gq/11   
5-Hydroxytryptamine receptors,5-HT3 HTR3 / 11   multisubunit    
5-Hydroxytryptamine receptors,5-HT4 HTR4 / 5q31 - 33   7TM Gs   
5-Hydroxytryptamine receptors,5-ht5A HTR5A / 7q36    none identified   
5-Hydroxytryptamine receptors,5-ht5B htr5b / 2q11-q13    none identified   
5-Hydroxytryptamine receptors,5-ht6 HTR6 / 1p35 -36    Gs   
5-Hydroxytryptamine receptors,5-HT7 HTR7 / 10q23.3-24.3    Gs   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Acetylcholine receptors,MuscarinicM1 CHRM1 / 11q12-13 ACh  7TM  Gq/11  ? ANS,CNS 
Acetylcholine receptors,MuscarinicM2 CHRM2 / 7q35-36 ACh  7TM  Gi/o  ? ANS,CNS 
Acetylcholine receptors,MuscarinicM3 CHRM3 / 1q43-44 ACh  7TM  Gq/11  ? ANS,CNS 
Acetylcholine receptors,MuscarinicM4 CHRM4 / 11p12 -11.2 ACh  7TM  Gi/o  ? ANS,CNS 
Acetylcholine receptors,MuscarinicM5 CHRM5 / 15q26 ACh  7TM  Gq/11  ? ANS,CNS 
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Acetylcholine receptors,Nicotinicalpah 1, embryonic, adult  ACh, nic Cono, dT chan   Sk muscle 
Acetylcholine receptors,Nicotinicalpah 2  ACh, nic DHBE, dT chan   CNS 
Acetylcholine receptors,Nicotinicalpha 3  ACh, nic Cono, dT chan   ANS, CNS 
Acetylcholine receptors,Nicotinicalpha 4  ACh, nic DHBE, dT chan   CNS, sens gan 
Acetylcholine receptors,Nicotinicalpah 6  ACh, nic dT chan   CNS, av ret 
Acetylcholine receptors,Nicotinicalpha 7  ACh, nic Cono, dT chan   ANS, CNS 
Acetylcholine receptors,Nicotinicalpha 8 (avian)  ACh, nic dT chan   Ret, CNS 
Acetylcholine receptors,Nicotinicalpha 9  ACh dT chan   Pit, cochlea 
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Adenosine receptors,A1 ADORA1 / 1q32.1   7TM Gi/o   
Adenosine receptors,A2A ADORA2A / 22q11.2   7TM Gs   
Adenosine receptors,A2B ADORA2B / 17p11.2-12   7TM Gs   
Adenosine receptors,A3 ADORA3 / 1p13.3   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Adrenoceptors,alpha1alpha 1A ADRA1C /8 NA, AD KMD, SNAP 7TM Gq/11  
Adrenoceptors,alpha1alpha 1B ADRA1B / 5q33 AD=NA AH 7TM Gq/11  
Adrenoceptors,alpha1alpha 1D ADRA1D /20p13 AD=NA BMY 7TM Gq/11  
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Adrenoceptors,alpha2alpha 2A ADRA2A /10q23-25 AD, NA BRL 7TM Gi/o  
Adrenoceptors,alpha2alpha 2B ADRA2B / 2 AD, NA ARC 7TM Gi/o  
Adrenoceptors,alpha2alpha 2C ADRA2C / 4 AD, NA ARC 7TM Gi/o  
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Adrenoceptors,betabeta 1 ADRB1 / 10q24-26 NA, AD CGP 7TM Gs  
Adrenoceptors,betabeta 2 ADRB2 / 5q31-32 AD, NA ICI 7TM Gs  
Adrenoceptors,betabeta 3 ADRB3 /8p11-12 NA=AD SR, L 7TM Gs, Gi/0  
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Angiotensin receptors,AT1 AGTR1 / 3q21-25   7TM Gq/11, Gi/o   
Angiotensin receptors,AT2 AGTR2 / Xq22-23   7TM Gia2,3   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Atrial natriuretic peptide receptors,ANPA NPR1 / 1q21-q22   7TM    
Atrial natriuretic peptide receptors,ANPB NPR2 / 9p12-p21   7TM    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Bombesin receptors,BB1 BBR1 / 6q21-ter   7TM Gq/11   
Bombesin receptors,BB2 BBR2 / Xp22.13   7TM Gq/11   
Bombesin receptors,bb3+ BRS3 / Xq26-28   7TM Gq/11   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Bradykinin receptors,B1 BDKRB1 / 14q32   7TM Gq/11   
Bradykinin receptors,B2 BDKRB2 / 14q32.1-32.2   7TM Gq/11   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Calcitonin, amylin, CGRP and adrenomedullin receptors,calcitonin CALCR / 7q21.3 -7q21.3   7TM Gs/Gq   
Calcitonin, amylin, CGRP and adrenomedullin receptors,amylin CALCR / 7q21.3-7q21.3   7TM Gs   
Calcitonin, amylin, CGRP and adrenomedullin receptors,CGRP    7TM Gs   
Calcitonin, amylin, CGRP and adrenomedullin receptors,Adrenomedullin    7TM Gs   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Cannabinoid receptors,CB1 CNR1 / 6q14-15   7TM Gi/o   
Cannabinoid receptors,CB2 CNR2 / 1p35-36   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Chemokine receptors,CCCCR1 CCR1 / 3p21   7TM Gi/o  
Chemokine receptors,CCCCR2 CCR2 / 3p21   7TM Gi/o  
Chemokine receptors,CCCCR3 CCR3 / 3p21   7TM Gi/o  
Chemokine receptors,CCCCR4 CCR4 / 3p22   7TM Gi/o  
Chemokine receptors,CCCCR5 CCR5 /3p21   7TM Gi/o  
Chemokine receptors,CCCCR6 CCR6 /6q27   7TM Gi/o  
Chemokine receptors,CCCCR7 CCR7 / 17q12-21.2   7TM Gi/o  
Chemokine receptors,CCCCR8 CCR8 / 3p22-23   7TM Gi/o  
Chemokine receptors,CCCCR9 CCR9 / 3p21.3-22   7TM Gi/o  
Chemokine receptors,CCCCR10 GPR2 / 17q21.1-q21.3   7TM Gi/o  
Chemokine receptors,CCCCR11 NA / 3q22   7TM Gi/o  
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Chemokine receptors,CX3CCXCR1 IL8RA /2q35   7TM Gi/o  
Chemokine receptors,CX3CCXCR2 IL8RB / 2q35   7TM Gi/o  
Chemokine receptors,CX3CCXCR3 GPR9 / Xq13   7TM Gi/o  
Chemokine receptors,CX3CCXCR4 CXCR4 /2q21   7TM Gi/o  
Chemokine receptors,CX3CCXCR5 BLR1 / 11q23-q24   7TM Gi/o  
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Chemotactic peptide receptors,C3a C3AR1 / 12p13   7TM Gi/o / Gz   
Chemotactic peptide receptors,C5a C5AR / 19q13.3-13.4   7TM Gi/o / Gz / Ga16   
Chemotactic peptide receptors,fMLP FPR1 / 19q13.3   7TM Gi/o / Gz   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Cholecystokinin and gastrin receptors,CCK1 CCKAR / 4p16.2-15.1   7TM Gq/11 / Gs   
Cholecystokinin and gastrin receptors,CCK2 CCKBR / 11p15.4   7TM Gq/11   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Corticotropin-releasing factor rceptors,CRF1 CRHR1 / 17q21-22   7TM Gs   
Corticotropin-releasing factor rceptors,CRF2 CRHR2 / 7p21-p15   7TM Gs   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Dopamine receptors,D1 DRD1 / 5q35.1 DA, SKF SCH 7TM Gs  
Dopamine receptors,D2 DRD2 / 11q22-23 DA Raclo 7TM Gi/o  
Dopamine receptors,D3 DRD3 /3q13.3 DA Nafa 7TM Gi/o  
Dopamine receptors,D4 DRD4 /11p15.5 DA 7TM Gi/o  
Dopamine receptors,D5 DRD5 / 4p15.1-16.1 DA  7TM Gs  
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Endothelin receptors,ET-A EDNRA / 4   7TM Gq/11   
Endothelin receptors,ET-B EDNRB / 13q22   7TM Gq/11   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
GABA receptors,AGABA site  GABA,musc BIC Multisubunit chan, Cl   
GABA receptors,ABZ site  GABA,FlU FLU chan, mod GABA site    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
GABA receptors,BGABA-B  GABA, Bac Saclo 7TM heterodimer, K Gi/o  
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Galanin receptors,GAL1 GALNR / 18q23   7TM Gi/o   
Galanin receptors,gal2 GALNR2 / 17q25.3   7TM Gi/o, Gq/11   
Galanin receptors,gal3 GALNR3 / 22q13.1   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Glutamate receptors,IonotropicNMDA, Glutamate site    chan, Na/K/Ca    
Glutamate receptors,IonotropicNMDA, Glycine site        
Glutamate receptors,IonotropicAMPA    chan, Na/K/Ca    
Glutamate receptors,IonotropicKainate    chan, Na/K/Ca    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Glutamate receptors,Metabotropicmglu1 GRM1 / 6   7TM Gq/11   
Glutamate receptors,Metabotropicmglu2 GRM2 / 3   7TM Gi/o   
Glutamate receptors,Metabotropicmglu3 GRM3 / 7q21.1-21.2   7TM Gi/o   
Glutamate receptors,Metabotropicmglu4 GRM4   7TM Gi/o   
Glutamate receptors,Metabotropicmglu5 GRM5   7TM Gq/11   
Glutamate receptors,Metabotropicmglu6 GRM6 / 5q35   7TM Gi/o   
Glutamate receptors,Metabotropicmglu7 GRM7   7TM Gi/o   
Glutamate receptors,Metabotropicmglu8 GRM8 / 7q31.3-32.1   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Glycine receptors,glyR  gly, beta-alanine, taurine  pentamer, Chloride channel    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Glycoprotein hormone receptors,FSH receptor FSHR / 2p21-p16   7TM Gs   
Glycoprotein hormone receptors,LSH receptor LHCGR / 2p21   7TM Gs, Gq/11, Gi   
Glycoprotein hormone receptors,TSH receptor TSHR / 14q31   7TM all 4 families of G proteins   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Histamine receptors,H1 HRH1 / 3p14-p21   7TM Gq/11   
Histamine receptors,H2 HRH2 / 5   7TM Gs   
Histamine receptors,H3 HRH3   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Ins(1,4,5)P3(IP3) receptors,IP-3-1    chan, homotetramer    
Ins(1,4,5)P3(IP3) receptors,IP-3-2    chan, homotetramer    
Ins(1,4,5)P3(IP3) receptors,IP-3-3    chan, homotetramer    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Leukotriene receptors,BLT LTB4R / 14q11.2-12   7TM Gq/11 , Gi/o   
Leukotriene receptors,CysLT1 CYSLT1 / Xq13-21   7TM Gq/11   
Leukotriene receptors,CysLT2     Gq/11   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Lysophospholipid receptors,edg1 EDG1 / 1pter-1qter   7TM Gi/a1,3   
Lysophospholipid receptors,edg2 EDG2   7TM Gi/o   
Lysophospholipid receptors,edg3 EDG3 / 9q22.1-q22.2   7TM Gq / Gi/o   
Lysophospholipid receptors,edg4 EDG4   7TM Gq / Gi/o   
Lysophospholipid receptors,edg5 EDG5   7TM Gq   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Melanocortin receptors,MC1 MC1R / 16q24.3   7TM Gs   
Melanocortin receptors,MC2 MC2R / 18p11.2   7TM Gs   
Melanocortin receptors,MC3 MC3R / 20q13.2   7TM Gs   
Melanocortin receptors,MC4 MC4R / 18q22.3-22   7TM Gs   
Melanocortin receptors,MC5 MC5R / 18p11.2   7TM Gs   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Melatonin receptors,MT1 MTNR1A / 4q35.1   7TM Gi/o   
Melatonin receptors,MT2 MTNR1B / 11q21-22   7TM Gi/o   
Melatonin receptors,MT3        
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Neuropeptide Y receptors,Y1 NPY1R / 4q31.3-32   7TM Gi/o   
Neuropeptide Y receptors,Y2 NPY2R / 4q31   7TM Gi/o   
Neuropeptide Y receptors,Y4 NPY4R / 10q11.2   7TM Gi/o   
Neuropeptide Y receptors,Y5 NPY5R / 4q31.3-32   7TM Gi/o   
Neuropeptide Y receptors,Y6 NPY6R / 5q31   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Neurotensin receptors,NTS1 NTSR1 /20q13   7TM Gq/11   
Neurotensin receptors,nts2 NTSR2   7TM Gq/11   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Neurotrophin receptors,trkA NTRK1 / 1q21 -22   1TM    
Neurotrophin receptors,trkB NTRK2 / 9q22.1   1TM    
Neurotrophin receptors,trkC NTRK3 / 15q24-25   1TM    
Neurotrophin receptors,p75 NGFR / 17q21-22   1TM    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Opioid and opioid-like receptors,Delta Opioid Peptide OPRD / 1p34.3-36.1   7TM Gi/o   
Opioid and opioid-like receptors,Kappa Opioid Peptide OPRK / 8q11.2   7TM Gi/o   
Opioid and opioid-like receptors,Mu Opioid Peptide OPRM / 6q24-25   7TM Gi/o   
Opioid and opioid-like receptors,N/OFQ receptor OPRL   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
P2X receptors (transmitter-gated channels),P2X1 P2RX1 / 17p13.3   2TM    
P2X receptors (transmitter-gated channels),P2X2 P2RX2   2TM    
P2X receptors (transmitter-gated channels),P2X3 P2RX3 / 11q12   2TM    
P2X receptors (transmitter-gated channels),P2X4 P2RX4 / 12q24.32   2TM    
P2X receptors (transmitter-gated channels),P2X5 P2RX5   2TM    
P2X receptors (transmitter-gated channels),P2X6 P2RX6   2TM    
P2X receptors (transmitter-gated channels),P2X7 P2RX7 / 12q24   2TM    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
P2Y receptors (G-protein-coupled),P2Y1 P2RY1 / 3q25   7TM Gq/11   
P2Y receptors (G-protein-coupled),P2Y2 P2RY2 / 11q13.5-14.1   7TM Gq/11   
P2Y receptors (G-protein-coupled),P2Y4 P2RY4 / Xq13   7TM Gq/11   
P2Y receptors (G-protein-coupled),P2Y6 P2RY6 / 11q13.3-13.5   7TM Gq/11   
P2Y receptors (G-protein-coupled),p2y11 P2RY11   7TM Gs Gq/11   
P2Y receptors (G-protein-coupled),P2YADP     Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Peroxisome proliferator activated receptors,PPAR-alpha PPARA / 22q12-q13.1       
Peroxisome proliferator activated receptors,PPAR-beta PPARD / 6p21.2-21.1       
Peroxisome proliferator activated receptors,PPAR-gama PPARG / 3p25       
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Prostanoid receptors,DP PTGDR   7TM Gs   
Prostanoid receptors,FP PTGFR / 1p31.1   7TM Gq/11   
Prostanoid receptors,IP PTGIR / 19q13.3   7TM Gs   
Prostanoid receptors,TP TBXA2R / 19p13.3   7TM Gq/11   
Prostanoid receptors,EP1 PTGER1 / 19q13.1   7TM Gq/11   
Prostanoid receptors,EP2 PTGER2 / 14q22   7TM Gs   
Prostanoid receptors,EP3 PTGER3 / 1p31.2   7TM Gq/11 / Gi/o / Gs   
Prostanoid receptors,EP4 PTGER4 / 5p13.1   7TM Gs   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Protease-activated receptors,PAR1 F2R / 5q13   7TM Gq/11 Gi/o / G12/13   
Protease-activated receptors,PAR2 F2RL1 / 5q13   7TM    
Protease-activated receptors,PAR3 F2RL2 / 5q13   7TM    
Protease-activated receptors,PAR4 F2RL3 / 19p12   7TM    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Ryanodine receptors,RY1    chan, homotetramer    
Ryanodine receptors,RY2    chan, homotetramer    
Ryanodine receptors,RY3    chan, homotetramer    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Somatostatin receptors,sst1 SSTR1 / 14q13   7TM Gi/o   
Somatostatin receptors,sst2 SSTR2 / 17q24   7TM Gi/o   
Somatostatin receptors,sst3 SSTR3 / 22p13.1   7TM Gi/o   
Somatostatin receptors,sst4 SSTR4 / 20p11.2   7TM Gi/o   
Somatostatin receptors,sst5 SSTR5 / 16p13.3   7TM Gi/o   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Steroid hormone receptors,Mineralocorticoid MLR / 4q31.1 /2   7TM    
Steroid hormone receptors,Glucocorticoid GRL / 5q31-32   7TM    
Steroid hormone receptors,Progesterone PGR / 11q22.1-22.3   7TM    
Steroid hormone receptors,Androgen AR / Xq11-12   7TM    
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Tachykinin receptors,NK1 TACR1 / 2   7TM Gq/11   
Tachykinin receptors,NK2 TACR2 / 10q11-21   7TM Gq/11   
Tachykinin receptors,NK3 TACR3 / 4   7TM Gq/11   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Thyrotropin-releasing hormone receptors,TRH1 TRHR / 8q23   7TM Gq   
Thyrotropin-releasing hormone receptors,trh2* trhr2   7TM Gq   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Vasoactive intentinal peptide and pituitary adenylate cyclase activating peptide receptors,VPAC1 VIPR1 / 3p22   7TM Gs   
Vasoactive intentinal peptide and pituitary adenylate cyclase activating peptide receptors,VPAC2 VIPR2 / 7q36.3   7TM Gs   
Vasoactive intentinal peptide and pituitary adenylate cyclase activating peptide receptors,PAC1 ADCYAP1R1 / 7p14   7TM Gs   
To PageTop


ReceptorsubtypeGene/ChromosomeAgonistAntagonistStructureCoupling2nd messageLocation
Vasopressin and oxytocin receptors,V1a AVPR1A / 12q14-15   7TM Gq/11   
Vasopressin and oxytocin receptors,V1b AVPR3 / 1q32   7TM Gq/11   
Vasopressin and oxytocin receptors,V2 AVPR2 / Xq28   7TM Gs   
Vasopressin and oxytocin receptors,OT OXTR / 3p26-25   7TM Gq/11, Gi   
To PageTop

Reference:

Alexander, S.P.H. and Peters, J.A. (2000) Receptor and Ion Channel Nomenclature Supplement. Trends in Pharmacological Sciences