136. Lu SM, Guido W and Sherman SM. (1993) The brain-stem parabrachial region controls mode of response to visual stimulation of neurons in the cat's lateral geniculate nucleus. Vis Neurosci 10:631-42.

NeuronCompartmentPropertyConnectivityNotes
Thalamus geniculate nucleus/lateral principal neuronSomaNicotinicAfferents from the parabrachial region (T)Leads to a fast EPSP which allows an influx of cations. This can work with the M1 receptors to switch the cell from burst to tonic mode (McCormick DA and Prince DA, 1987 [guinea-pig and cat ]134 , Lu SM et al, 1993 [cat ]136 , reviewed in McCormick DA, 1989135 , SOBIV p317).
Thalamus geniculate nucleus/lateral principal neuronMiddle equivalent dendriteM1Afferents from the parabrachial region (T)Slow second messeger pathway that leads to a reduction in K+ current. This can switch the cell from burst to tonic mode (McCormick DA and Prince DA, 1987 [guinea-pig and cat ]134 , Lu SM et al, 1993 [cat ]136 , reviewed in McCormick DA, 1989135 , SOBIV p317).
Thalamus geniculate nucleus/lateral principal neuronMiddle equivalent dendriteNicotinicAfferents from the parabrachial region (T)Leads to a fast EPSP which allows an influx of cations. This can work with the M1 receptors to switch the cell from burst to tonic mode (McCormick DA and Prince DA, 1987 [guinea-pig and cat ]134 , Lu SM et al, 1993 [cat ]136 , reviewed in McCormick DA, 1989135 , SOBIV p317).
Thalamus geniculate nucleus/lateral principal neuronProximal equivalent dendriteM1Afferents from the parabrachial region (T)Slow second messeger pathway that leads to a reduction in K+ current. This can switch the cell from burst to tonic mode (McCormick DA and Prince DA, 1987 [guinea-pig and cat ]134 , Lu SM et al, 1993 [cat ]136 , reviewed in McCormick DA, 1989135 , SOBIV p317).
Thalamus geniculate nucleus/lateral principal neuronProximal equivalent dendriteNicotinicAfferents from the parabrachial region (T)Leads to a fast EPSP which allows an influx of cations. This can work with the M1 receptors to switch the cell from burst to tonic mode (McCormick DA and Prince DA, 1987 [guinea-pig and cat ]134 , Lu SM et al, 1993 [cat ]136 , reviewed in McCormick DA, 1989135 , SOBIV p317).

References
134. McCormick DA and Prince DA. (1987) Actions of acetylcholine in the guinea-pig and cat medial and lateral geniculate nuclei, in vitro. J Physiol 392:147-65.
136. Lu SM, Guido W and Sherman SM. (1993) The brain-stem parabrachial region controls mode of response to visual stimulation of neurons in the cat's lateral geniculate nucleus. Vis Neurosci 10:631-42.
135. McCormick DA. (1989) Cholinergic and noradrenergic modulation of thalamocortical processing. Trends Neurosci 12:215-21.
_8/14/2018 10:10:54 AM