148. Lipowsky R, Gillessen T and Alzheimer C. (1996) Dendritic Na+ channels amplify EPSPs in hippocampal CA1 pyramidal cells. J Neurophysiol 76:2181-91 [Journal] .

NeuronCompartmentPropertyConnectivityNotes
Hippocampus CA1 pyramidal cellProximal apical dendritemGluR---Extracelluar ACPD (an mGluR agonist) application to apical or basal dendrites of CA1 pyramidal neurons causes local increases in calcium concentration that propagate throughout the cell, as measured by simultaneous whole cell recording and confocal microscopy with calcium imaging (Jaffe DB and Brown TH, 1994 [rat ]146 ), suggesting the presence of mGluRs. Lipowsky R et al, 1996 [rat ]148 provide evidence that activation of these receptors is necessary for LTP induction
Hippocampus CA1 pyramidal cellProximal apical dendriteI Na,p.Whole-cell somatic recording during TTX application to proximal dendrites suggests the presence of a persistent Na current (Lipowsky R et al, 1996 [rat ]148 ).

References
146. Jaffe DB and Brown TH. (1994) Metabotropic glutamate receptor activation induces calcium waves within hippocampal dendrites. J Neurophysiol 72:471-4.
148. Lipowsky R, Gillessen T and Alzheimer C. (1996) Dendritic Na+ channels amplify EPSPs in hippocampal CA1 pyramidal cells. J Neurophysiol 76:2181-91 [Journal] .
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