16. Chen WR and Shepherd GM. (1997) Membrane and synaptic properties of mitral cells in slices of rat olfactory bulb. Brain Res 745:189-96.

NeuronCompartmentPropertyConnectivityNotes
Olfactory receptor neuronAxon terminalGlutamate.Electrophysiology data: AP5 attenuates delayed excitatory components in peristimulus time histograms of mitral cell unit responses to olfactory nerve volleys (Ennis M et al, 1996 [rat ]20 ). Electrophysiology data: DNQX attenuates early and late excitatory components in peristimulus time histograms of mitral cell unit responses to olfactory nerve volleys (Ennis M et al, 1996 [rat ]20 ). Intracellular recordings: AP5 blocks late component of EPSP elicited by olfactory nerve volley (Berkowicz DA et al, 1994 [turtle ]10 ). Intracellular recordings: AP5 blocks late component of EPSP response to olfactory nerve volley (Chen WR and Shepherd GM, 1997 [rat ]16 ). Intracellular recordings: CNQX blocks early component of EPSP elicited by olfactory nerve volley (Berkowicz DA et al, 1994 [turtle ]10 ). Intracellular recordings: CNQX blocks early component of EPSP response to olfactory nerve volley (Chen WR and Shepherd GM, 1997 [rat ]16 ).
Olfactory bulb main mitral cellSomaI A.Delayed firing of action potentials in response to current pulse injection suggests there is I A current here. Unpublished data have characterized the kinetics of A current in the rat mitral cell (Chen WR and Shepherd GM, 1997 [rat ]16 ). Using whole-cell recordings, the kinetic properties of this current have been investigated in neurones from neonatal rats, which were retrogradely labelled and identified after enzymatic dissociation (Wang XY et al, 1996 [rat ]2 ).
Olfactory bulb main mitral cellDistal apical dendriteAMPA.Intracellular recordings: CNQX blocks early component of EPSP elicited by olfactory nerve volley nerve volley (Berkowicz DA et al, 1994 [turtle ]10 ). Electrophysiology data: DNQX attenuates early and late excitatory components in peristimulus time histograms of mitral cell unit responses to olfactory nerve volleys (Ennis M et al, 1996 [rat ]20 ). Intracellular recordings: CNQX blocks early component of EPSP response to olfactory nerve volley (Chen WR and Shepherd GM, 1997 [rat ]16 ). Paired whole-cell recording revealed reciprocal excitatory connections between mitral cells. Pharmacological analysis suggested that it could be mediated by both AMPA and NMDA receptors (Urban NN and Sakmann B, 2002469 ).
Olfactory bulb main mitral cellDistal apical dendriteNMDA.Intracellular recordings: AP5 blocks late component of EPSP elicited by olfactory nerve volley (Berkowicz DA et al, 1994 [turtle ]10 ). Electrophysiology data: AP5 attenuates delayed excitatory components in peristimulus time histograms of mitral cell unit responses to olfactory nerve volleys (Ennis M et al, 1996 [rat ]20 ). Intracellular recordings: AP5 blocks late component of EPSP response to olfactory nerve. volley (Chen WR and Shepherd GM, 1997 [rat ]16 ). Paired whole-cell recording revealed reciprocal excitatory connections between mitral cells. Pharmacological analysis suggested that it could be mediated by both AMPA and NMDA receptors (Urban NN and Sakmann B, 2002469 ).
Olfactory bulb main tufted middle cellDistal apical dendriteAMPA.Intracellular recordings: CNQX blocks early component of EPSP elicited by olfactory nerve volley nerve volley (Berkowicz DA et al, 1994 [turtle ]10 ). Electrophysiology data: DNQX attenuates early and late excitatory components in peristimulus time histograms of mitral cell unit responses to olfactory nerve volleys (Ennis M et al, 1996 [rat ]20 ). Intracellular recordings: CNQX blocks early component of EPSP response to olfactory nerve volley (Chen WR and Shepherd GM, 1997 [rat ]16 ). Paired whole-cell recording revealed reciprocal excitatory connections between mitral cells. Pharmacological analysis suggested that it could be mediated by both AMPA and NMDA receptors (Urban NN and Sakmann B, 2002469 ).
Olfactory bulb main tufted middle cellDistal apical dendriteNMDA.Intracellular recordings: AP5 blocks late component of EPSP elicited by olfactory nerve volley (Berkowicz DA et al, 1994 [turtle ]10 ). Electrophysiology data: AP5 attenuates delayed excitatory components in peristimulus time histograms of mitral cell unit responses to olfactory nerve volleys (Ennis M et al, 1996 [rat ]20 ). Intracellular recordings: AP5 blocks late component of EPSP response to olfactory nerve. volley (Chen WR and Shepherd GM, 1997 [rat ]16 ). Paired whole-cell recording revealed reciprocal excitatory connections between mitral cells. Pharmacological analysis suggested that it could be mediated by both AMPA and NMDA receptors (Urban NN and Sakmann B, 2002469 ).
Olfactory bulb main tufted middle cellSomaI A.Delayed firing of action potentials in response to current pulse injection suggests there is I A current here. Unpublished data have characterized the kinetics of A current in the rat mitral cell (Chen WR and Shepherd GM, 1997 [rat ]16 ). Using whole-cell recordings, the kinetic properties of this current have been investigated in neurones from neonatal rats, which were retrogradely labelled and identified after enzymatic dissociation (Wang XY et al, 1996 [rat ]2 ).

References
20. Ennis M, Zimmer LA and Shipley MT. (1996) Olfactory nerve stimulation activates rat mitral cells via NMDA and non-NMDA receptors in vitro. Neuroreport 7:989-92.
10. Berkowicz DA, Trombley PQ and Shepherd GM. (1994) Evidence for glutamate as the olfactory receptor cell neurotransmitter. J Neurophysiol 71:2557-61 [Journal] .
16. Chen WR and Shepherd GM. (1997) Membrane and synaptic properties of mitral cells in slices of rat olfactory bulb. Brain Res 745:189-96.
2. Wang XY, McKenzie JS and Kemm RE. (1996) Whole-cell K+ currents in identified olfactory bulb output neurones of rats. J Physiol 490 ( Pt 1):63-77 [Journal] .
469. Urban NN and Sakmann B. (2002) Reciprocal intraglomerular excitation and intra- and interglomerular lateral inhibition between mouse olfactory bulb mitral cells. J Physiol 542:355-67.
_9/22/2018 9:10:01 PM