183. Magee JC and Cook EP. (2000) Somatic EPSP amplitude is independent of synapse location in hippocampal pyramidal neurons. Nat Neurosci 3:895-903.

NeuronCompartmentPropertyConnectivityNotes
Hippocampus CA1 pyramidal cellDistal apical dendriteGlutamatePerforant pathway entorhinal pyramidal neuron terminals (T)Glutamate is commonly believed to be the primary excitatory neurotransmitter in the hippocampal formation generally (reviewed in Cotman et al., 1995), and in CA1 in particular (Storm-Mathisen J, 1977141 , Randall AD and Collingridge GL, 1992142 ). CA1 pyramidal neurons increase their firing (recorded extracellularly) in response to ionophoresed Glu within their apical dendritic fields or in the cell body layer (Dudar 1974 PMID#4437726). Magee JC and Cook EP, 2000183

References
141. Storm-Mathisen J. (1977) Localization of transmitter candidates in the brain: the hippocampal formation as a model. Prog Neurobiol 8:119-81.
142. Randall AD and Collingridge GL. (1992) Amino acid receptor-mediated synaptic currents in the CA1 region of the hippocampus. Ion Channels 3:63-81.
183. Magee JC and Cook EP. (2000) Somatic EPSP amplitude is independent of synapse location in hippocampal pyramidal neurons. Nat Neurosci 3:895-903.
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