1. Llinás R and Sugimori M. (1980) Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices. J Physiol 305:171-95.

NeuronCompartmentPropertyConnectivityNotes
Cerebellum Purkinje GABA cellSomaI Na,p.Sensitive to TTX. This plateau potential underlies impulse bursting (Llinás R and Sugimori M, 1980 [guinea pig]1 ).
Cerebellum Purkinje GABA cellSomaI Na,t.Sensitive to TTX. This generates the impulses that propagate into the axon (Llinás R and Sugimori M, 1980 [guinea pig]1 ). Simultaneous whole-cell recordings, made from the soma and dendrites rat brain slices, showed that AP evoked by either current pulses or synaptic stimulation of parallel or climbing fibers, always occurred first at the soma and decreased in amplitude with increasing distance into the dendrites. Simultaneous somatic and axonal recordings showed that these action potentials were initiated in the axon (Stuart G and Häusser M, 19942 ). The kinetics properties of this current were studied using whole-cell recording from dissociated neurons. Unlike other cells, recovery from inactivation was accompanied by a sizeable ionic current. It was suggested that the current flowing during this recovery may depolarize the cells immediately after an AP, promoting the typical high-frequency firing of these neurons (complex spike) (Raman IM and Bean BP, 20013 ). NaV1.1 is present in the soma and proximal dendrites, NaV1.6 is robustly present in cell bodies and dendrites, and NaV1.7 is absent from the cell (Ahn HS et al, 20114 ). (Schaller KL and Caldwell JH, 20035 ). (Dib-Hajj SD et al, 20106 ).
Cerebellum Purkinje GABA cellSomaI K,Ca.(Llinás R and Sugimori M, 1980 [guinea pig]1 ). reviewed in Llinas and Walton, 1990).
Cerebellum Purkinje GABA cellSomaI K.a fast voltage activated potassium current that generates the afterhyperpolarization following a fast spike." (data from (Llinás R and Sugimori M, 1980 [guinea pig]1 ). quote from the review in Llinas and Walton 1990).

Classical References: first publications on each compartmental property; search PubMed for complete list
1.  Llinás R and Sugimori M. (1980) Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices. J Physiol 305:171-95.
2.  Stuart G and Häusser M. (1994) Initiation and spread of sodium action potentials in cerebellar Purkinje cells. Neuron 13:703-12.
3.  Raman IM and Bean BP. (2001) Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms. Biophys J 80:729-37 [Journal] .
4.  Ahn HS, Black JA, Zhao P, Tyrrell L, Waxman SG and Dib-Hajj SD. (2011) Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons. Mol Pain 7:32 [Journal] .
5.  Schaller KL and Caldwell JH. (2003) Expression and distribution of voltage-gated sodium channels in the cerebellum. Cerebellum 2:2-9 [Journal] .
6.  Dib-Hajj SD, Cummins TR, Black JA and Waxman SG. (2010) Sodium channels in normal and pathological pain. Annu Rev Neurosci 33:325-47 [Journal] .