Neuron | Compartment | Property | Connectivity | Notes |
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Neostriatum medium spiny direct pathway GABA cell | Soma | I L high threshold | . | Whole-cell voltage-clamp recordings showed that HVA currents were present in at least 95% of neostriatal neurons, but that the majority of them appeared to belong neither to the "L-type" nor the "N-type" classification (Hoehn K et al, 1993 [rat]1 ). However, recordings in slices showed that D1 receptor activation can either inhibit or enhance evoked activity, depending on the level of membrane depolarization, by modulating an L-type Ca2+ conductance (Hernández-López S et al, 19972 ). |
Neostriatum medium spiny direct pathway GABA cell | Soma | I N | . | Whole-cell voltage-clamp recordings showed that HVA currents were present in at least 95% of neostriatal neurons, but that the majority of them appeared to belong neither to the "L-type" nor the "N-type" classification (Hoehn K et al, 1993 [rat]1 ). |
Neostriatum medium spiny direct pathway GABA cell | Soma | I T low threshold | . | Whole-cell voltage-clamp recordings showed that a low-threshold transient (T-type) Ca2+ current was observed in 40% of neurons (Hoehn K et al, 1993 [rat]1 ). Another study suggested that adult neostriatal projection neurons do not express significant levels of LVA Ca2+ current (Bargas J et al, 1994 [rat]3 ). |