220. Kang J, Huguenard JR and Prince DA. (2000) Voltage-gated potassium channels activated during action potentials in layer V neocortical pyramidal neurons. J Neurophysiol 83:70-80 [Journal] .

NeuronCompartmentPropertyConnectivityNotes
Neocortex V1 pyramidal corticothalamic L6 cellSomaI K,Ca.Dual patch-clamp recordings showed that Ca-activated K+ (BK) channels were not triggered by neuronal action potentials in normal slices and only opened as neuronal responses deteriorated (smaller or absent spikes) and in a spike-independent manner, suggesting that BK channels may activate only in pathological conditions (Kang J et al, 2000 [rat ]220 ). Intracellular recordings from sensorimotor cortex suggested that what activate IKCa persistently would not be calcium but some biochemical modification triggered by NMDA receptor activation (Kitagawa H et al, 2000 [cat ]221 ). Ca2+-activated K+ currents were studied using whole-cell patch-clamp recordings from freshly dissociated mouse neocortical pyramidal neurons (Sun X et al, 2003480 ).
Neocortex M1 pyramidal corticothalamic L6 cellSomaI K,Ca.Dual patch-clamp recordings showed that Ca-activated K+ (BK) channels were not triggered by neuronal action potentials in normal slices and only opened as neuronal responses deteriorated (smaller or absent spikes) and in a spike-independent manner, suggesting that BK channels may activate only in pathological conditions (Kang J et al, 2000 [rat ]220 ). Intracellular recordings from sensorimotor cortex suggested that what activate IKCa persistently would not be calcium but some biochemical modification triggered by NMDA receptor activation (Kitagawa H et al, 2000 [cat ]221 ). Ca2+-activated K+ currents were studied using whole-cell patch-clamp recordings from freshly dissociated mouse neocortical pyramidal neurons (Sun X et al, 2003480 ).

References
220. Kang J, Huguenard JR and Prince DA. (2000) Voltage-gated potassium channels activated during action potentials in layer V neocortical pyramidal neurons. J Neurophysiol 83:70-80 [Journal] .
221. Kitagawa H, Nishimura Y, Kumazawa Y, Akamine T and Yamamoto T. (2000) Activity-dependent slow hyperpolarization in cat sensorimotor cortex in vitro. Brain Res 869:69-77.
480. Sun X, Gu XQ and Haddad GG. (2003) Calcium influx via L- and N-type calcium channels activates a transient large-conductance Ca2+-activated K+ current in mouse neocortical pyramidal neurons. J Neurosci 23:3639-48.
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