1. van den Pol AN. (1995) Presynaptic metabotropic glutamate receptors in adult and developing neurons: autoexcitation in the olfactory bulb. J Comp Neurol 359:253-71 [Journal] .

NeuronCompartmentPropertyConnectivityNotes
Olfactory bulb main mitral GLU cellSomamGluR1.Synaptic inhibition of mitral cells: Yamamoto et al, 1962; (PHILLIPS CG et al, 1963 [rabbit]2 ). granule cell dendrodendritic synapses: (Rall W et al, 19663 ). (Rall W and Shepherd GM, 19684 ). granule cells are GABAergic: (Ribak CE et al, 19775 ). Auto-activation from glutamate released by mitral cell soma (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main mitral GLU cellDistal apical dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main mitral GLU cellDistal basal dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main mitral GLU cellMiddle basal dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main mitral GLU cellProximal basal dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main mitral GLU cellMiddle apical dendriteNMDA.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ). Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells (Isaacson JS, 19996 ).
Olfactory bulb main mitral GLU cellProximal apical dendriteNMDA.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ). Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells (Isaacson JS, 19996 ). The pharmacology and kinetics of glutamate sensitivity of mitral cells was studied using flash photolysis in rats (Lowe G, 20037 ).
Olfactory bulb main tufted middle GLU cellSomamGluR1.Synaptic inhibition of mitral cells: Yamamoto et al, 1962; (PHILLIPS CG et al, 1963 [rabbit]2 ). granule cell dendrodendritic synapses: (Rall W et al, 19663 ). (Rall W and Shepherd GM, 19684 ). granule cells are GABAergic: (Ribak CE et al, 19775 ). Auto-activation from glutamate released by mitral cell soma (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main tufted middle GLU cellDistal apical dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main tufted middle GLU cellDistal basal dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main tufted middle GLU cellMiddle basal dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main tufted middle GLU cellProximal basal dendritemGluR1.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main tufted middle GLU cellMiddle apical dendriteNMDA.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ). Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells (Isaacson JS, 19996 ).
Olfactory bulb main tufted middle GLU cellProximal apical dendriteNMDA.Auto-activation from glutamate released by mitral cell secondary dendrites (van den Pol AN, 1995 [rat]1 ). Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells (Isaacson JS, 19996 ). The pharmacology and kinetics of glutamate sensitivity of mitral cells was studied using flash photolysis in rats (Lowe G, 20037 ).
Olfactory bulb main mitral GLU cellDistal apical dendriteGlutamate.Implied by Glu released by other compartments of the mitral cell (Dale's law). Target (destination) is presumably PG cell dendrites in the glomerulus (van den Pol AN, 1995 [rat]1 ).
Olfactory bulb main tufted middle GLU cellDistal apical dendriteGlutamate.Implied by Glu released by other compartments of the mitral cell (Dale's law). Target (destination) is presumably PG cell dendrites in the glomerulus (van den Pol AN, 1995 [rat]1 ).

Classical References: first publications on each compartmental property; search PubMed for complete list
1.  van den Pol AN. (1995) Presynaptic metabotropic glutamate receptors in adult and developing neurons: autoexcitation in the olfactory bulb. J Comp Neurol 359:253-71 [Journal] .
2.  PHILLIPS CG, POWELL TP and SHEPHERD GM. (1963) RESPONSES OF MITRAL CELLS TO STIMULATION OF THE LATERAL OLFACTORY TRACT IN THE RABBIT. J Physiol 168:65-88.
3.  Rall W, Shepherd GM, Reese TS and Brightman MW. (1966) Dendrodendritic synaptic pathway for inhibition in the olfactory bulb. Exp Neurol 14:44-56.
4.  Rall W and Shepherd GM. (1968) Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb. J Neurophysiol 31:884-915 [Journal] .
5.  Ribak CE, Vaughn JE, Saito K, Barber R and Roberts E. (1977) Glutamate decarboxylase localization in neurons of the olfactory bulb. Brain Res 126:1-18.
6.  Isaacson JS. (1999) Glutamate spillover mediates excitatory transmission in the rat olfactory bulb. Neuron 23:377-84.
7.  Lowe G. (2003) Flash photolysis reveals a diversity of ionotropic glutamate receptors on the mitral cell somatodendritic membrane. J Neurophysiol 90:1737-46 [Journal] .