1. Deniau JM, Mailly P, Maurice N and Charpier S. (2007) The pars reticulata of the substantia nigra: a window to basal ganglia output. Prog Brain Res 160:151-72 [Journal] .

NeuronCompartmentPropertyConnectivityNotes
Substantia nigra pars reticulata principal GABA cellDistal equivalent dendriteGabaAstriatonigral and pallidonigral inputThe reversal potential as well asthe complete blockade of the striatal-evokedsynaptic events by bicuculline or picrotoxin indicatethat neurotransmission between striatonigralfibers and SNr cells is due to activation of GABAAreceptors with chloride ions as charge carriers" (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellMiddle equivalent dendriteGabaAstriatonigral and pallidonigral inputThe reversal potential as well asthe complete blockade of the striatal-evokedsynaptic events by bicuculline or picrotoxin indicatethat neurotransmission between striatonigralfibers and SNr cells is due to activation of GABAAreceptors with chloride ions as charge carriers" (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellProximal equivalent dendriteGabaAstriatonigral and pallidonigral inputThe reversal potential as well asthe complete blockade of the striatal-evokedsynaptic events by bicuculline or picrotoxin indicatethat neurotransmission between striatonigralfibers and SNr cells is due to activation of GABAAreceptors with chloride ions as charge carriers" (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellDistal equivalent dendriteGabaBstriatonigral and pallidonigral inputThe presence of GABAB receptor subtypes BR1 and BR2 on the presynaptic and postsynaptic membranes of GABAergic striatonigral synapses and glutamatergic STN like terminals indicates that besides GABAA, GABAB receptors are also implicated in GABAergic striatonigral transmission." (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellMiddle equivalent dendriteGabaBstriatonigral and pallidonigral inputThe presence of GABAB receptor subtypes BR1 and BR2 on the presynaptic and postsynaptic membranes of GABAergic striatonigral synapses and glutamatergic STN like terminals indicates that besides GABAA, GABAB receptors are also implicated in GABAergic striatonigral transmission." (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellProximal equivalent dendriteGabaBstriatonigral and pallidonigral inputThe presence of GABAB receptor subtypes BR1 and BR2 on the presynaptic and postsynaptic membranes of GABAergic striatonigral synapses and glutamatergic STN like terminals indicates that besides GABAA, GABAB receptors are also implicated in GABAergic striatonigral transmission." (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellDistal equivalent dendriteNMDA subthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellMiddle equivalent dendriteNMDAsubthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellProximal equivalent dendriteNMDAsubthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellProximal equivalent dendriteAMPAsubthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellMiddle equivalent dendriteAMPAsubthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellDistal equivalent dendriteAMPAsubthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellDistal equivalent dendritemGluR1subthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellMiddle equivalent dendritemGluR1subthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellProximal equivalent dendritemGluR1subthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellDistal equivalent dendritemGluR5subthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellMiddle equivalent dendritemGluR5subthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellProximal equivalent dendritemGluR5subthalamonigral inputIn vivo, the excitatory influence of STN contributes to the tonic discharge of SNr cells as shown by the marked reduction in SNr firing rate induced by a pharmacological blockade of STN activity (Féger J and Robledo P, 19912 ). The effects of glutamate on SNr cells is mediated by the three principal types of glutamate receptors: a-amino 3hydroxy-5methyl- 4-isoxaline propionic acid/kainate (AMPA), N-methyl-D aspartate (NMDA) and metabotropic receptors [mGluR1 and mGluR5]” Reviewed in (Deniau JM et al, 20071 ).
Substantia nigra pars reticulata principal GABA cellAxon terminalGabaThalamic and cortical connectionsFrom rodents to primates, the SNr and GPi innervate thalamic and brain stem nuclei connected to motor, prefrontal, parietal and temporal associative cortical areas offering an access for BG to control motor, cognitive, as well as emotional–motivational processes.” (Deniau JM et al, 20071 ).

Classical References: first publications on each compartmental property; search PubMed for complete list
1.  Deniau JM, Mailly P, Maurice N and Charpier S. (2007) The pars reticulata of the substantia nigra: a window to basal ganglia output. Prog Brain Res 160:151-72 [Journal] .
2.  Féger J and Robledo P. (1991) The Effects of Activation or Inhibition of the Subthalamic Nucleus on the Metabolic and Electrophysiological Activities Within the Pallidal Complex and Substantia Nigra in the Rat. Eur J Neurosci 3:947-952.