237. Nisenbaum ES and Wilson CJ. (1995) Potassium currents responsible for inward and outward rectification in rat neostriatal spiny projection neurons. J Neurosci 15:4449-63.

NeuronCompartmentPropertyConnectivityNotes
Neostriatum spiny direct pathway neuronSomaI A.The contribution of a fast (IAt), and a slowly (IAs)-inactivating A-currents were studied in slices. The results suggest a role for these currents to define the limits on the depolarized state (Nisenbaum ES and Wilson CJ, 1995237 ). With whole-cell patch clamp, two types of A-current were found in rat neostriatal neurons, one similar to previous descriptions in mammals and a second activated at considerably more depolarized potentials (Surmeier DJ et al, 1989239 ). A slowly inactivating A current has also been studied (Gabel LA and Nisenbaum ES, 1998246 ).
Neostriatum spiny direct pathway neuronSomaI h.The contribution of an inwardly rectifying current (IKir) were studied in slices. The results suggest that the hyperpolarized state is determined principally by this current (Nisenbaum ES and Wilson CJ, 1995237 ).
Neostriatum spiny direct pathway neuronSomaI Potassium.A slow, noninactivating current may have a role to define the limits on the depolarized state, and to govern the spike discharge characteristics once the depolarized state has been reached (Nisenbaum ES and Wilson CJ, 1995237 ). A non-inactivating, Ca-independent, K+ current may limit the amplitude of membrane depolarizations associated with prolonged excursions into the depolarized state (Nisenbaum ES et al, 1996 [rat ]242 ).

References
237. Nisenbaum ES and Wilson CJ. (1995) Potassium currents responsible for inward and outward rectification in rat neostriatal spiny projection neurons. J Neurosci 15:4449-63.
239. Surmeier DJ, Bargas J and Kitai ST. (1989) Two types of A-current differing in voltage-dependence are expressed by neurons of the rat neostriatum. Neurosci Lett 103:331-7.
246. Gabel LA and Nisenbaum ES. (1998) Biophysical characterization and functional consequences of a slowly inactivating potassium current in neostriatal neurons. J Neurophysiol 79:1989-2002.
242. Nisenbaum ES, Wilson CJ, Foehring RC and Surmeier DJ. (1996) Isolation and characterization of a persistent potassium current in neostriatal neurons. J Neurophysiol 76:1180-94 [Journal] .
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