238. Surmeier DJ and Kitai ST. (1993) D1 and D2 dopamine receptor modulation of sodium and potassium currents in rat neostriatal neurons. Prog Brain Res 99:309-24.

NeuronCompartmentPropertyConnectivityNotes
Neostriatum spiny direct pathway neuronSomaD1.Activation of both D1- and D2-class receptors has been shown to modulate potassium and sodium currents in acutely isolated neostriatal neurons (Surmeier DJ and Kitai ST, 1993238 ).Recordings in slices showed that D1 receptor activation can either inhibit or enhance evoked activity, depending on the level of membrane depolarization, by modulating an L-type Ca2+ conductance (Hernandez-Lopez S et al, 1997241 ).
Neostriatum spiny direct pathway neuronSomaD2.Activation of both D1- and D2-class receptors has been shown to modulate potassium and sodium currents in acutely isolated neostriatal neurons (Surmeier DJ and Kitai ST, 1993238 ).

References
238. Surmeier DJ and Kitai ST. (1993) D1 and D2 dopamine receptor modulation of sodium and potassium currents in rat neostriatal neurons. Prog Brain Res 99:309-24.
241. Hernandez-Lopez S, Bargas J, Surmeier DJ, Reyes A and Galarraga E. (1997) D1 receptor activation enhances evoked discharge in neostriatal medium spiny neurons by modulating an L-type Ca2+ conductance. J Neurosci 17:3334-42.
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