263. Reyes-Harde M, Potter BV, Galione A and Stanton PK. (1999) Induction of hippocampal LTD requires nitric-oxide-stimulated PKG activity and Ca2+ release from cyclic ADP-ribose-sensitive stores. J Neurophysiol 82:1569-76.

NeuronCompartmentPropertyConnectivityNotes
Hippocampus CA1 pyramidal cellProximal apical dendriteNO.Experimental findings support a cascade for induction of homosynaptic, NO-dependent LTD involving activation of guanylyl cyclase, production of guanosine 3',5' cyclic monophosphate and subsequent PKG activation. This process has an additional requirement for release of Ca2+ from ryanodine-sensitive stores (Reyes-Harde M et al, 1999263 ).
Hippocampus CA3 pyramidal cellAxon terminalNO.Experimental findings support a cascade for induction of homosynaptic, NO-dependent LTD involving activation of guanylyl cyclase, production of guanosine 3',5' cyclic monophosphate and subsequent PKG activation. This process has an additional requirement for release of Ca2+ from ryanodine-sensitive stores (Reyes-Harde M et al, 1999263 ).

References
263. Reyes-Harde M, Potter BV, Galione A and Stanton PK. (1999) Induction of hippocampal LTD requires nitric-oxide-stimulated PKG activity and Ca2+ release from cyclic ADP-ribose-sensitive stores. J Neurophysiol 82:1569-76.
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