344. Marek GJ and Aghajanian GK. (1995) Protein kinase C inhibitors enhance the 5-HT2A receptor-mediated excitatory effects of serotonin on interneurons in rat piriform cortex. Synapse 21:123-30 [Journal] .

NeuronCompartmentPropertyConnectivityNotes
Olfactory cortex anterior interneuron deep layerDistal equivalent dendrite5-HT2.A subpopulation of interneurons in layer III of the rat piriform cortex are excited by 5-hydroxytryptamine (5-HT) via 5-HT2A receptors and by norepinephrine via alpha 1-adrenoceptors. (Marek GJ and Aghajanian GK, 1996343 ) 5-HT excites 5-HT2 receptors in interneurons and 5-HT1C receptors in pyramidal neurons (Sheldon PW and Aghajanian GK, 1991346 ), (Sheldon PW and Aghajanian GK, 1990347 ) PKC may have a negative feedback role in modulating excitation by 5-HT in piriform cortical interneurons (Marek GJ and Aghajanian GK, 1995344 ).

References
343. Marek GJ and Aghajanian GK. (1996) Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons. Eur J Pharmacol 305:95-100.
346. Sheldon PW and Aghajanian GK. (1991) Excitatory responses to serotonin (5-HT) in neurons of the rat piriform cortex: evidence for mediation by 5-HT1C receptors in pyramidal cells and 5-HT2 receptors in interneurons. Synapse 9:208-18 [Journal] .
347. Sheldon PW and Aghajanian GK. (1990) Serotonin (5-HT) induces IPSPs in pyramidal layer cells of rat piriform cortex: evidence for the involvement of a 5-HT2-activated interneuron. Brain Res 506:62-9.
344. Marek GJ and Aghajanian GK. (1995) Protein kinase C inhibitors enhance the 5-HT2A receptor-mediated excitatory effects of serotonin on interneurons in rat piriform cortex. Synapse 21:123-30 [Journal] .
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